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From Bioblast
Year | Reference | Mammal and model | Tissue and cell | Stress | Diseases | |
---|---|---|---|---|---|---|
Spinazzi 2019 Proc Natl Acad Sci U S A | 2019 | Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, Agostinis P, Maia TM, Impens F, Morais VA, Lopez-Lluch G, Serneels L, Navas P, De Strooper B (2019) PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. Proc Natl Acad Sci U S A 116:277-86. 10.1073/pnas.1811938116 | Mouse | Nervous system | Neurodegenerative | |
Stankova 2010 Toxicol In Vitro | 2010 | Staňková P, Kučera O, Lotková H, Roušar T, Endlicher R, Cervinková Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103. | Liver | Oxidative stress;RONS | ||
Stein 2018 Cell Rep | 2018 | Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20. | Human | Heart Skeletal muscle | ||
Stepanova 2016 Biochim Biophys Acta | 2016 | Stepanova A, Shurubor Y, Valsecchi F, Manfredi G, Galkin A (2016) Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart. Biochim Biophys Acta 1857:1561-8. | Mouse | Heart Nervous system | ||
Stepanova 2017 J Cereb Blood Flow Metab | 2017 | Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58. | Mouse | Nervous system | Ischemia-reperfusion | |
Stepanova 2018 J Cereb Blood Flow Metab | 2018 | Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab 39:1790-802. | Rat | Nervous system | Hypoxia Ischemia-reperfusion | |
Stepanova 2019 Antioxid Redox Signal | 2019 | Stepanova Anna, Sosunov S, Niatsetskaya Z, Konrad Csaba, Starkov AA, Manfredi G, Wittig I, Ten V, Galkin A (2019) Redox-dependent loss of flavin by mitochondrial complex I in brain ischemia/reperfusion injury. Antioxid Redox Signal 31:608-22. | Mouse | Nervous system | Ischemia-reperfusion | |
Stier 2013 Front Zool | 2013 | Stier A, Bize P, Schull Q, Zoll J, Singh F, Geny B, Gros F, Royer C, Massemin S, Criscuolo F (2013) Avian erythrocytes have functional mitochondria, opening novel perspectives for birds as animal models in the study of ageing. Front Zool 10:33. | Mouse Birds | Blood cells | Oxidative stress;RONS | Aging;senescence |
Stride 2013 Eur J Heart Fail | 2013 | Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F (2013) Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 15:150-7. | Human | Heart | Mitochondrial disease | |
Suhane 2013 Bio Open | 2013 | Suhane S, Kanzaki H, Arumugaswami V, Murali R, VK (2013) Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells. Bio Open 2:295-305. | HEK | Oxidative stress;RONS | Cancer | |
Sumbalova 2011 Abstract Bordeaux | Sumbalova Z, Wiethuechter A, Fasching M, Gnaiger E (2011) Coupling control and substrate control of mitochondrial membrane potential and respiration in the mouse brain, and comparison with skeletal and cardiac muscle. Abstract MiP2011, Bordeaux. | Mouse | Nervous system | |||
Szczepanowska 2016 EMBO J | 2016 | Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83. | Mouse | Heart | ||
Szczepanowska 2020 Nat Commun | 2020 | Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Höhne MN, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, Müller S, Frese CK, Brandt U, Riemer J, Wittig I, Trifunovic A (2020) A salvage pathway maintains highly functional respiratory complex I. Nat Commun 11:1643. | Caenorhabditis elegans | |||
Szczerbinski 2021 Cells | 2021 | Szczerbinski L, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Szczerbinski K, Goscik J, Gorska M, Larsen S, Kretowski A (2021) The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes. Cells 10:3013. | Human | Skeletal muscle Fat | Diabetes | |
Szibor 2019 Biochim Biophys Acta Bioenerg | 2019 | Szibor Marten, Gainutdinov Timur, Fernandez-Vizarra Erika, Dufour Eric, Gizatullina Zemfira, Debska-Vielhaber Grazyna, Heidler Juliana, Wittig Ilka, Viscomi Carlo, Gellerich Frank Norbert, Moore Anthony L (2019) Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: switch from RET and ROS to FET. Biochim Biophys Acta Bioenerg 1861:148137. | Mouse | Heart | ||
Takada 2022 Proc Natl Acad Sci U S A | 2022 | Takada S, Maekawa S, Furihata T, Kakutani N, Setoyama D, Ueda K, Nambu H, Hagiwara H, Handa H, Fumoto Y, Hata S, Masunaga T, Fukushima A, Yokota T, Kang D, Kinugawa S, Sabe H (2022) Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure. Proc Natl Acad Sci U S A 119: e2203628119. | Mouse | Heart | Cardiovascular | |
Takahashi 2017 Exp Gerontol | 2017 | Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2017) Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria. Exp Gerontol 98:217-223. | Mouse | Nervous system | Aging;senescence | |
Tegelberg 2017 Orphanet J Rare Dis | 2017 | Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73. | Human Mouse | Blood cells Platelet | Other | |
Teh 2015 Oncogene | 2015 | Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304. | Human | Other cell lines | Cancer | |
Tello 2011 Cell Metab | 2011 | Tello D, Balsa E, Acosta-Iborra B, Fuertes-Yebra E, Elorza A, Ordóñez Á, Corral-Escariz M, Soro I, López-Bernardo E, Perales-Clemente E, Martínez-Ruiz A, Enríquez JA, Aragonés J, Cadenas S, Landázuri MO (2011) Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity. Cell Metab 14:768-79. | Mouse | Fibroblast | Ischemia-reperfusion Oxidative stress;RONS | |
Tepp 2011 Biochim Biophys Acta | 2011 | Tepp K, Shevchuk I, Chekulayev V, Timohhina N, Kuznetsov AV, Guzun R, Saks V, Kaambre T (2011) High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units. Biochim Biophys Acta 1807: 1549-1561. | Heart | |||
Terwilliger 2021 Vasc Med | 2021 | Terwilliger ZS, Ryan TE, Goldberg EJ, Schmidt CA, Yamaguchi DJ, Karnekar R, Brophy P, Green TD, Zeczycki TN, Mac Gabhann F, Annex BH, McClung JM (2021) Racial differences in the limb skeletal muscle transcriptional programs of patients with critical limb ischemia. Vasc Med 26:247-58. | Human | Skeletal muscle | Cardiovascular | |
Thiede 2012 Biochim Biophys Acta | 2012 | Thiede A, Gellerich FN, Schönfeld P, Siemen D (2012) Complex effects of 17β-estradiol on mitochondrial function. Biochim Biophys Acta 1817:1747-53. | Rat | Nervous system Liver | ||
Thomas 2016 Neurodegeneration Therapeutics | 2016 | Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41. | Rat | Nervous system | Mitochondrial disease | |
Thome 2019 Am J Physiol Cell Physiol | 2019 | Thome T, Salyers ZR, Kumar RA, Hahn D, Berru FN, Ferreira LF, Scali ST, Ryan TE (2019) Uremic metabolites impair skeletal muscle mitochondrial energetics through disruption of the electron transport system and matrix dehydrogenase activity. Am J Physiol Cell Physiol 317:C701-13. | Mouse | Skeletal muscle | Other | |
Thompson 2018 EMBO Mol Med | 2018 | Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060. | Drosophila | |||
Tioli 2019 MiP2019 | Involvement of mitochondrial respiratory supercomplexes in anti-bacterial innate immunity. | Mouse | Heart Liver Blood cells Macrophage-derived | Infectious | ||
Trefts 2019 Am J Physiol Endocrinol Metab | 2019 | Trefts E, Hughey CC, Lantier L, Lark DS, Boyd KL, Pozzi A, Zent R, Wasserman DH (2019) Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and the postabsorptive response of mice in an age-dependent manner. Am J Physiol Endocrinol Metab 316:1118-35. | Mouse | Liver | ||
Trefts 2019 Thesis | 2019 | Trefts E (2019) Integrin linked kinase is critical for hepatic cellular organization, metabolism, and glucoregulation. PhD Thesis 164. | Mouse | Liver | Other | |
Trewin 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H2O2 release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016. | Human | Skeletal muscle | ||
Trifunovic 2019 MiP2019 | Keeping mitochondria in shape. | |||||
Trimmer 2009 Mol Neurodegener | 2009 | Trimmer PA, Schwartz KM, Borland MK, De Taboada L, Streeter J, Oron U (2009) Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy. Mol Neurodegener 4:26. | Human | Nervous system | Parkinson's | |
Trumbeckaite 2001 Eur J Biochem | 2001 | Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN (2001) Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. Eur J Biochem 268:1422-9. | Rabbit | Heart Skeletal muscle | ||
Trumbeckaite 2013 Mitochondrion | 2013 | Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN (2013) Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801. Mitochondrion 13:539–47. | Rat | Nervous system | Ischemia-reperfusion | |
Tyagi 2018 Sci Rep | 2018 | Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S (2018) SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep 8:17547. | Mouse | Nervous system | ||
Usui 2012 Eur J Anaes | 2012 | Usui D, Isaksson M, Suzuki M, Sjovall F, Elmer E, Uchino H (2012) The influence of anesthetic agents on mitochondrial function as determined by high‐resolved respirometry of human blood cells: 9AP7‐9. Eur J Anaes 29:150. | Human | Blood cells Platelet | ||
Vaka 2017 Hypertension | Abstract P265: Placental ischemia causes renal mitochondrial impairment in reduced uterine perfusion pressure rats. | Rat | Kidney Genital | Ischemia-reperfusion | ||
Vaka 2019 Am J Physiol Regul Integr Comp Physiol | 2019 | Vaka VR, Mcmasters KM, Cornelius DC, Ibrahim T, Jayaram A, Usry N, Cunningham MW Jr, Amaral LM, LaMarca BD (2019) Natural killer cells contribute to mitochondrial dysfunction in response to placental ischemia in Reduced Uterine Perfusion Pressure (RUPP) rats. Am J Physiol Regul Integr Comp Physiol 316:R441-R447. | Human Rat | Endothelial;epithelial;mesothelial cell Genital | Ischemia-reperfusion Oxidative stress;RONS | |
Van Bergen 2014 Mitochondrion | 2014 | Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33. | Human Mouse | Nervous system Blood cells | ||
Van Hoose 2015 Thesis | 2015 | Van Hoose P (2015) Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. Dissertations p128. | Mouse | Heart | Ischemia-reperfusion | Cardiovascular |
Van Hoose 2016 J Nutr Biochem | 2016 | Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16. | Mouse | Heart | Ischemia-reperfusion | Cardiovascular |
Van Rahden 2015 Am J Hum Genet | 2015 | van Rahden VA, Fernandez-Vizarra E, Alawi M, Brand K, Fellmann F, Horn D, Zeviani M, Kutsche K (2015) Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome. Am J Hum Genet 96:640-50. | Human | HeLa | Cell death | Other |
Van Zutphen 2016 J Hepatol | 2016 | van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208. | Rat | Liver | ||
Van den Berg 2017 Am J Respir Crit Care Med | 2017 | van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC (2017) Diaphragm atrophy and weakness in the absence of mitochondrial dysfunction in the critically ill. Am J Respir Crit Care Med 196:1544-58. | Human | Skeletal muscle | Other | |
Vatrinet 2015 Abstract MiP2015 | Targeting complex I as an anticancer strategy. | Human | Oxidative stress;RONS | Cancer | ||
Vella 2019 MiPschool Coimbra | Genetic variants in mitochondrial respiratory chain complex deficiencies. | Mitochondrial disease | ||||
Venediktova 2020 Mitochondrion | 2020 | Venediktova NI, Mashchenko OV, Talanov EY, Belosludtseva NV, Mironova GD (2020) Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism. Mitochondrion 52:190-96. | Rat | Liver | Other | |
Vercellino 2021 Nature | 2021 | Vercellino I, Sazanov LA (2021) Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV. Nature 598:364-367. doi: 10.1038/s41586-021-03927-z | Mouse | |||
Vercellino 2022 Nat Rev Mol Cell Biol | 2022 | Vercellino I, Sazanov LA (2022) The assembly, regulation and function of the mitochondrial respiratory chain. Nat Rev Mol Cell Biol 23:141-161. doi: 10.1038/s41580-021-00415-0 | ||||
Verkhovskaya 2014 Biochim Biophys Acta | 2014 | Verkhovskaya M, Wikström M (2014) Oxidoreduction properties of bound ubiquinone in Complex I from Escherichia coli. Biochim Biophys Acta 1837:246-50. https://doi.org/10.1016/j.bbabio.2013.11.001 |