Bioblast alert 2022

Bioblast alert - 2022

Bioblast alert 2022(06) - Parkinson's disease: 2022-04-11

Reviewing cellular models to decipher the mechanisms of mitochondrial dysfunction in Parkinson's disease

Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002

from the O2k-Networks »RS Belgrade Lalic NM«, »UK Nottingham Chakrabarti L« and »UK Leicester Moisoi N«

"Early stage α-synuclein pathology does not influence mitochondrial respiration in the striatum and amygdala"

Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. - »Bioblast link«

from the O2k-Network »CH Lausanne Place N« and »CH Lausanne Sandi C«

Dominant mutation in Parkinson’s Disease causes loss of protein function in mitochondria

Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W (2020) CHCHD2 harboring the Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet [Epub ahead of print]. - »Bioblast link«

from the O2k-Network »FR Angers Gueguen N« and »BE Leuven Spinazzi M«

Bioblast alert 2022(05) - Upcoming events: 2022-03-25

10^th Conference of the International Coenzyme Q10 Association 2022, Hamburg DE

Date: May 12-15
Oroboros participation:

May 14: Oroboros O2k-Lunch Workshop - »MiPNet27.01 IOC152 Hamburg DE«
May 14: 16:30 (GMT+2): Erich Gnaiger presenting - The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ₂

European Society for Clinical Investigation (ESCI) 56th Annual meeting 2022, Bari IT

Date: June 8-10
Abstract submission: possible until March 28
Oroboros participation:

June 8: Erich Gnaiger presenting - Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts

Bioblast 2022: BEC Inaugural Conference, Innsbruck AT

Date: June 28 - July 1
Abstract submission: possible until April 1

EBEC2022, Marseille FR

Date: August 20-25
Abstract submission: possible until June 1
Oroboros participation:

Oroboros will be present with a booth

Bioblast alert 2022(04) - Respiration of fibroblasts: 2022-03-18

From MitoFit Preprint to peer-reviewed publication

Addressing the question whether respiration differs in attached versus suspended cells using multiwell respirometry and high-resolution respirometry

Zdrazilova L, Hansikova H, Gnaiger E (2022) Comparable respiratory activity in attached and suspended human fibroblasts. PLoS ONE 17:e0264496. »Bioblast link«

from the O2k-Network »AT Innsbruck Oroboros« , »CZ Prague Zeman J«

Meta-analysis

Gnaiger E (2021) Bioenergetic cluster analysis – mitochondrial respiratory control in human fibroblasts. MitoFit Preprints 2021.8 https://doi.org/10.26124/mitofit:2021-0008

from the O2k-Network »AT Innsbruck Oroboros«

Bioblast alert 2022(03) - Science for Ukraine: 2022-03-07

Scientific and humanitarian organizations join the world-wide protest against the Russian aggression-war in Ukraine. Oroboros declares solidarity with protests in Russia and outside Russia against this war.

Support for Ukraine women in science

Oroboros Instruments offers 1-year scientific positions to help Ukraine women to pursue their scientific career and gain expertise in bioenergetics: in mitochondrial and cell respiration, photobiology. If war makes a prolonged stay necessary, we are open to extend the contract – in the spirit of Gentle Science.

-» Please, contact us at [email protected]

The Oroboros Bioenergetics Adventurers – our international team of scientists – are enthusiastic to collaborate with colleagues from Ukraine, who require support at the time of war, with a background in cell biology – mitochondrial physiology or algal photosynthesis. If you intend to return home when science can be continued in Ukraine, we will support you with a donation of our internationally leading instrument, represented in 49 countries. The running costs are low. For the latest information, see:

Zdrazilova L, Hansikova H, Gnaiger E (2022) Comparable respiratory activity in attached and suspended human fibroblasts. PLoS ONE 17:e0264496. doi:10.1371/journal.pone.0264496

Bioblast alert 2022(02) - TissueModels: 2022-02-18

Publication from the TissueModels project: exploring serum-free culture media

Oemer G, Edenhofer ML, Wohlfarter Y, Lackner K, Leman G, Koch J, Cardoso LHD, Lindner HH, Gnaiger E, Dubrac S, Zschocke J, Keller MA (2021) Fatty acyl availability modulates cardiolipin composition and alters mitochondrial function in HeLa cells. J Lipid Res 100111. »Bioblast link«

from the O2k-Network »AT Innsbruck Oroboros«

Open position for TissueModels

Postdoctoral Fellow in mitochondrial physiology and membrane lipids at the Medical University Innsbruck, Institute of Human Genetics working in close collaboration with Oroboros Instruments.

»Position description« and »TissueModels«

Bioblast alert 2022(01) - Bioenerg Commun: 2022-02-09

Living Communications address the conflict between (R) rapid sharing of new methods and results, (E) efficient prevention of exponentially increasing numbers of publications, and (C) quality control as a time-demanding and expensive instrument to ensure reproducibility.

Gnaiger E (2021) Beyond counting papers – a mission and vision for scientific publication. Bioenerg Commun 2021.5. doi:10.26124/bec:2021-0005

from the O2k-Network »AT Innsbruck Oroboros«

Reductive stress or hyperoxic oxidative stress?

Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. Bioenerg Commun 2021.4. doi:10.26124/BEC:2021-0004

from the O2k-Network »AT Innsbruck Oroboros« and »CZ Hradec Kralove Cervinkova Z«