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Triethyltin bromide

From Bioblast

high-resolution terminology - matching measurements at high-resolution

Triethyltin bromide


Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial ATP synthase [2] which is used to induce LEAK state in living cells of Saccharomyces cerevisiae.

Abbreviation: TET

Contributed by Kandolf G 2016-02-08

Chemical formula: (C2H5)3SnBr

Synonym: Bromotriethylstannane



  1. Aguilaniu H, Gustafsson L, Rigoulet M, Nystrรถm T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404. Bioblast Link
  2. Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. Open Access]
  3. Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. Bioblast Link

MitoPedia topics: Inhibitor