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ASK Query
[[Category:Publications]] [[Coupling states::ET]]
SQL Query
SELECT DISTINCT
  t0.smw_id AS id,
  t0.smw_title AS t,
  t0.smw_namespace AS ns,
  t0.smw_iw AS iw,
  t0.smw_subobject AS so,
  t0.smw_sortkey AS sortkey, t0.smw_sort
FROM
  `smw_object_ids` AS t0
INNER JOIN
  (`smw_fpt_inst` AS t2
INNER JOIN
  `t3` AS t3 ON t2.o_id=t3.id
INNER JOIN
  `smw_di_blob` AS t4 ON t2.s_id=t4.s_id) ON t0.smw_id=t2.s_id
WHERE
  (
   ((t4.o_hash='ET') AND t4.p_id=80919)
  )
  AND t0.smw_iw!=':smw'
  AND t0.smw_iw!=':smw-delete'
  AND t0.smw_iw!=':smw-redi'
ORDER BY
  t0.smw_sort ASC
LIMIT
  55
OFFSET
  500
SQL Explain
IDselect_typetabletypepossible_keyskeykey_lenrefrowsfilteredExtra
1SIMPLEt3ALLPRIMARY7100.00Using temporary; Using filesort
Auxilliary Tables
  • Temporary table t3
      Recursively computed hierarchy for element(s) (80971).
      SELECT s_id FROM `smw_fpt_subc` WHERE o_id=80971 LIMIT 1
Query Metrics
Query-Size:3
Query-Depth:1
Errors and Warnings
None
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Doerrier 2012 Abstract BioblastDoerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.LEAK
OXPHOS
ET
N
S
NS
Permeabilized tissueMouseHeart
Doerrier 2014 Abstract SECFEvaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissue
Isolated mitochondria
MouseHeart
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.LEAK
OXPHOS
ET
N
S
NS
Homogenate
Isolated mitochondria
MouseLiver
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.LEAK
OXPHOS
ET
N
S
NS
Permeabilized tissue
Isolated mitochondria
MouseHeart
Liver
Doerrier 2016 Abstract MitoFit Science Camp 2016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
ROX
Permeabilized cells
Permeabilized tissue
Homogenate
Isolated mitochondria
Human
Mouse
Heart
Blood cells
HEK
Platelet
Doerrier 2016 Mitochondrion2016Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueMouseHeart
Doerrier 2016b Abstract Mito Xmas Meeting InnsbruckSearching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.LEAK
OXPHOS
ET
F
N
S
Gp
CIV
ROX
Isolated mitochondriaMouseHeart
Doerrier 2017 Abstract MitoEAGLE Barcelona
COST Action MitoEAGLE

SUIT reference protocol for comparative mitochondrial physiology.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
Permeabilized cells
Homogenate
Isolated mitochondria
Human
Mouse
Heart
Nervous system
HEK
Doerrier 2017 MiP2017 C1
Carolina Anneliese Doerrier

Effects of warm ischemia on cardiac mitochondria to detect specific targets by high-resolution respirometry (HRR)

LEAK
ET
F
N
S
CIV
NS
Isolated mitochondriaMouseHeart
Doerrier 2017 MiP2017 WG2
Carolina Anneliese Doerrier

Upper limit of OXPHOS capacity in permeabilized myofibers: effect of oxygen, ADP and blebbistatin in MiR05Cr and Buffer Z.

LEAK
OXPHOS
ET
N
NS
Permeabilized tissueMouseSkeletal muscle
Doerrier 2017 MiPschool C2
DoerrierC.JPG

Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
Permeabilized cells
Homogenate
Isolated mitochondria
Human
Mouse
Heart
Nervous system
HEK
Doerrier 2018 EBEC2018
Carolina Anneliese Doerrier

Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
Other combinations
ROX
Permeabilized cells
Homogenate
Isolated mitochondria
Human
Mouse
Heart
Nervous system
Blood cells
HEK
Platelet
Doerrier 2018 ESCI2018
Carolina Anneliese Doerrier

High-resolution respirometry, two techniques combined in one to explore mitochondrial function in health and disease

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
ROX
CIV
Permeabilized cells
Permeabilized tissue
Homogenate
Isolated mitochondria
Human
Mouse
Heart
Skeletal muscle
Nervous system
Blood cells
HEK
Doerrier 2018 Methods Mol Biol2018Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
Other combinations
ROX
Permeabilized cells
Permeabilized tissue
Homogenate
Isolated mitochondria
Intact cells
Human
Mouse
Rat
Saccharomyces cerevisiae
Heart
Skeletal muscle
Endothelial;epithelial;mesothelial cell
Blood cells
HEK
Platelet
Doerrier 2018 MiP2018a
Carolina Anneliese Doerrier

Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.

LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueMouseSkeletal muscle
Doerrier 2018 MiP2018c
Carolina Doerrier

Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation.

LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueHumanSkeletal muscle
Doerrier 2019 MiP2019
Carolina Doerrier

Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers.

LEAK
ET
N
S
NS
ROX
Permeabilized tissueHumanSkeletal muscle
Doerrier 2019 MitoFit Preprint Arch EA2019Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueHumanSkeletal muscle
Doerrier 2020 PaduaMuscleDays PosterDoerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized tissueHuman
Mouse
Skeletal muscle
Doerrier 2022 MitoFit NADHDoerrier C, Cardoso LHD, Gnaiger E (2022) Simultaneous measurement of oxygen consumption and NAD(P)H/NAD(P)+-redox state in isolated mitochondria. (in prep)LEAK
OXPHOS
ET
NIsolated mitochondriaMouseLiver
Dogan 2014 Cell Metab2014Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69.LEAK
OXPHOS
ET
N
S
Permeabilized tissue
Isolated mitochondria
MouseHeart
Skeletal muscle
Liver
Dohlmann 2014 Abstract MiP2014Mitochondrial adaptations to high-intensity training in young and elderly men and women.OXPHOS
ET
Permeabilized cellsHumanSkeletal muscle
HeLa
Fibroblast
Dohlmann 2018 Physiol Rep2018Dohlmann TL, Hindsø M, Dela F, Helge JW, Larsen S (2018) High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle. Physiol Rep 6:e13857.OXPHOS
ET
N
NS
Permeabilized tissueHumanSkeletal muscle
Fat
Doig 2019 bioRxiv2019Doig CD, Zelinska AE, Oakey LA, Fletcher RS, El Hassan Y, Garten A, Cartwright D, Heising S, Tennant DA, Watson D, Adamski J, Lavery GG (2019) Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice. bioRxiv doi: https://doi.org/10.1101/567297 .LEAK
OXPHOS
ET
F
N
S
NS
ROX
Permeabilized tissueMouseSkeletal muscle
Doig 2020 Skelet Muscle2020Doig CL, Zielinska AE, Fletcher RS, Oakey LA, Elhassan YS, Garten A, Cartwright D, Heising S, Alsheri A, Watson DG, Prehn C, Adamski J, Tennant DA, Lavery GG (2020) Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction. Skelet Muscle 10:5.LEAK
OXPHOS
ET
F
N
S
NS
ROX
Permeabilized tissueMouseSkeletal muscle
Dollerup 2019 J Physiol2019Dollerup OL, Chubanava S, Agerholm M, Søndergård SD, Altıntaş A, Møller AB, Høyer KF, Ringgaard S, Stødkilde-Jørgensen H, Lavery GG, Barres R, Larsen S, Prats C, Jessen N, Treebak JT (2019) Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men. J Physiol 598:731-54.LEAK
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized tissueHumanSkeletal muscle
Dominguez-Amorocho 2019 MiP2019
MiPsociety

Role of Sirtuin 1/3 in CD4+ T cells activation and differentiation in obese and transplanted animals.

LEAK
ET
OXPHOS
ROXMouseLymphocyte
Dong 2024 Nat Commun2024Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H (2024) Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease. https://doi.org/10.1038/s41467-023-44057-6LEAK
OXPHOS
ET
N
S
CIV
NS
HomogenateMouseLiver
Donnarumma 2022 Nat Commun2022Donnarumma E, Kohlhaas M, Vimont E, Kornobis E, Chaze T, Gianetto QG, Matondo M, Moya-Nilges M, Maack C, Wai T (2022) Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure. https://doi.org/10.1038/s41467-022-34316-3LEAK
OXPHOS
ET
F
N
S
CIV
Isolated mitochondriaMouseHeart
Donnelly 2024 Redox Biol2024Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion A-C, Matera A, Tavernari D, Campiche O, Paolicelli RC, Zanou N, Kayser B, Gnaiger E, Place N (2024) Functional hypoxia reduces mitochondrial calcium uptake. Redox Biol 71:103037. https://doi.org/10.1016/j.redox.2024.103037LEAK
OXPHOS
ET
N
S
NS
ROX
Intact organism
Isolated mitochondria
Intact cells
Human
Mouse
Heart
Skeletal muscle
Doridot 2014 Antioxid Redox Signal2014Doridot LD Chatre LD, Ducat A, Vilotte JL, Lombes A, Méhats C, Barbaux S, Calicchio R, Ricchetti M, Vaiman D (2014) Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia associated gene. Antioxid Redox Signal 21:819-34.LEAK
ROUTINE
ET
ROXHumanEndothelial;epithelial;mesothelial cell
Other cell lines
Dorigatti 2021 Geroscience2021Dorigatti JD, Thyne KM, Ginsburg BC, Salmon AB (2021) Beta-guanidinopropionic acid has age-specific effects on markers of health and function in mice. Geroscience 43:1497-511.LEAK
OXPHOS
ET
N
S
NS
ROX
F
Permeabilized tissueMouseSkeletal muscle
Dos Santos 2013 Bio Open2013Dos Santos RS, Galina A, Da-Silva WS (2013) Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle. Bio Open 2:82-7.LEAK
OXPHOS
ET
N
S
Permeabilized tissue
Isolated mitochondria
FishesSkeletal muscle
Dos Santos 2013 J Bioenerg Biomembr2013dos Santos RS, Peçanha FL, da-Silva WS (2013) Functional characterization of an uncoupling protein in goldfish white skeletal muscle. J Bioenerg Biomembr 45:243-51.LEAK
OXPHOS
ET
SIsolated mitochondriaFishesSkeletal muscle
Doucet 2018 Mol Pharmacol2018Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH (2018) Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Mol Pharmacol 95:139-50.LEAK
ROUTINE
ET
ROXIntact cellsHumanPlatelet
Blood cells
Douros 2019 JCI Insight2019Douros JD, Niu J, Sdao SM, Gregg T, Fisher-Wellman KH, Bharadwaj MS, Molina A, Arumugam R, Martin MD, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell JE, D'Alessio D (2019) Sleeve gastrectomy rapidly enhances islet function independently of body weight. JCI Insight 4:126688.LEAK
OXPHOS
ET
N
Gp
NS
Permeabilized tissueMouseIslet cell;pancreas;thymus
Drake 2021 Proc Natl Acad Sci U S A2021Drake JC, Wilson RJ, Laker RC, Guan Y, Spaulding HR, Nichenko AS, Shen W, Shang H, Dorn MV, Huang K, Zhang M, Bandara AB, Brisendine MH, Kashatus JA, Sharma PR, Young A, Gautam J, Cao R, Wallrabe H, Chang PA, Wong M, Desjardins EM, Hawley SA, Christ GJ, Kashatus DF, Miller CL, Wolf MJ, Periasamy A, Steinberg GR, Hardie DG, Yan Z (2021) Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy. Proc Natl Acad Sci U S A 118:e2025932118.LEAK
OXPHOS
ET
N
S
NS
Permeabilized tissueMouseSkeletal muscle
Drechsler 2015 Intensive Care Medicine Experimental2015Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.LEAK
OXPHOS
ET
N
S
HomogenateMouseLiver
Kidney
Dreher 2023 Int J Obes (Lond)2023Dreher SI, Irmler M, Pivovarova-Ramich O, Kessler K, Jürchott K, Sticht C, Fritsche L, Schneeweiss P, Machann J, Pfeiffer AFH, Hrabě de Angelis M, Beckers J, Birkenfeld AL, Peter A, Niess AM, Weigert C, Moller A (2023) Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention. https://doi.org/10.1038/s41366-023-01271-yOXPHOS
ET
F
N
NS
Permeabilized tissueHumanSkeletal muscle
Fat
Drehmer 2016 Stem Cell Res2016Drehmer DL, de Aguiar AM, Brandt AP, Petiz L, Cadena SM, Rebelatto CK, Brofman PR, Filipak Neto F, Dallagiovanna B, Abud AP (2016) Metabolic switches during the first steps of adipogenic stem cells differentiation. Stem Cell Res 17:413-421.LEAK
ROUTINE
ET
ROXIntact cellsHumanFat
Stem cells
Driescher 2019 Heliyon2019Driescher N, Joseph DE, Human VR, Ojuka E, Cour M, Hadebe N, Bester D, Marnewick JL, Lecour S, Lochner A, Essop MF (2019) The impact of sugar-sweetened beverage intake on rat cardiac function. Heliyon 5:e01357.LEAK
OXPHOS
ET
F
N
CIV
ROX
Permeabilized tissueRatHeart
Du 1998 Free Radic Biol Med1998Du G, Mouithys-Mickalad A, Sluse FE (1998) Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation. Free Radic Biol Med 25:1066-74.OXPHOS
ET
Du 1999 Free Radic Biol Med1999Du G, Willet K, Mouithys-Mickalad A, Sluse-Goffart CM, Droy-Lefaix M-T, Sluse FE (1999) EGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation. Free Radic Biol Med 27:596-604.OXPHOS
ET
Isolated mitochondriaRatLiver
Du 2015 Aquat Toxicol2015Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40.LEAK
OXPHOS
ET
N
S
CIV
ROX
Permeabilized cellsFishesLiver
Du 2015 J Biol Chem2015Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710.LEAK
ROUTINE
OXPHOS
ET
N
ROX
Isolated mitochondriaMouseNervous system
Islet cell;pancreas;thymus
Du 2016 Aquat Toxicol2016Du X, Crawford DL, Nacci DE, Oleksiak MF (2016) Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol 177:44-50.LEAK
OXPHOS
ET
N
S
CIV
Other combinations
ROX
Permeabilized cellsFishesLiver
Du 2016 J Exp Biol2016Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.LEAK
OXPHOS
ET
N
S
CIV
NS
Isolated mitochondriaFishesLiver
Du 2016 Thesis2016Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175.LEAK
OXPHOS
ET
S
CIV
ROX
N
NS
Permeabilized cellsFishesLiver
Du 2017 Evolution2017Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52.LEAK
OXPHOS
ET
N
NS
ROX
S
Isolated mitochondriaFishesLiver
Du 2018 Environ Sci Technol2018Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11.LEAK
ET
N
S
NS
Isolated mitochondriaFishesLiver
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