User talk:Beno Marija/My sandbox2012 MiPschool Programme: Difference between revisions

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==MiPsummer Programme==
==MiP''summer'' Programme==


::::FEBS workshop & MiPsummer School on Mitochondria at Cambridge 2012
::::FEBS workshop & MiP''summer School'' on Mitochondria at Cambridge 2012


::::*Final programme with poster presentations - [http://www.mitophysiology.org/fileadmin/user_upload/MiP/MiPsummer2012_Programme.pdf download pdf]
::::*Final programme with poster presentations - [http://www.mitophysiology.org/fileadmin/user_upload/MiP/MiP''summer''2012_Programme.pdf download pdf]
::::*Poster presentations
::::*Poster presentations


{| class="wikitable"
{|class='wikitable'
! Saturday, 7th July Arrival
|-
|-
|17:00: Registration (Bridgetower room)
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"|'''Saturday, 7th July Arrival'''
|-
|-
|20:00 - 20:15: Welcome to Cambridge (Lecture theatre)
|17:00
|Bridgetower room
|Registration
|-
|-
|20:15 - 21:15: Chuck Hoppel (Cleveland)
|20:00 - 20:15  
Mitochondrial physiology and functional testing in diagnosis of mitochondrial disease (Lecture theatre)
|Lecture theatre
|Welcome to Cambridge
|-
|-
|21:15: Reception (Terrace room)
|20:15 - 21:15  
|Cleveland
|Chuck Hoppel - Mitochondrial physiology and functional testing in diagnosis of mitochondrial disease (Lecture theatre)
|-
|21:15
|Terrace room
|Reception
|}
|}


{| class="wikitable"
{|class='wikitable'
! Sunday, 8th July
|-
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Sunday, 8th July'''
|-
|-
|09:00: Mitochondrial structure and respiratory function session (Graham Storey room)
|09:00
|Graham Storey room
|Mitochondrial structure and respiratory function session
|-
|-
|09:00 - 09:30: Erich Gnaiger (Innsbruck)
|09:00 - 09:30
Mitochondrial respiration: in vitro to in vivo
|Innsbruck
|Erich Gnaiger - Mitochondrial respiration: in vitro to in vivo
|-
|-
|09:30 - 10:00:Rodrigue Rossignol (Bordeaux)
|09:30 - 10:00
Mitochondrial structure, fission and networks
|Bordeaux
|Rodrigue Rossignol - Mitochondrial structure, fission and networks
|-
|-
|10:00 - 10:15: Steve Hand (Baton Rouge)
|10:00 - 10:15
Protein targeting and translocation into mitochondria
|Baton Rouge
|Steve Hand - Protein targeting and translocation into mitochondria
|-
|-
|10:15 - 10:30: Discussion
|10:15 - 10:30
|
|Discussion
|-
|-
|10:30: Coffee break (Dining Hall)
|10:30
|Dining Hall
|Coffee break  
|-
|-
|11:00 - 11:15:Shijun Xu (Gothenburg)
|11:00 - 11:15
Mitochondrial dynamics at single cell level
|Gothenburg
|Shijun Xu - Mitochondrial dynamics at single cell level
|-
|-
|11:15 - 11:30:Kel Sheldon (NIH)
|11:15 - 11:30
VDAC blockage by tubulin is the missing link of mitochondrial respiration control
|NIH
|Kel Sheldon - VDAC blockage by tubulin is the missing link of mitochondrial respiration control
|-
|-
|11:30 - 11:45: Marleen Forkink (Nijmegen)
|11:30 - 11:45
Inhibiting mitochondrial Complex I or Complex III differentially affects mitochondrial physiology
|Nijmegen
|Marleen Forkink - Inhibiting mitochondrial Complex I or Complex III differentially affects mitochondrial physiology
|-
|-
|11:45 - 12:00: Laura García Corzo (Granada)
|11:45 - 12:00
A new insight about molecular aspects of CoQ deficiency
|Granada
|Laura García Corzo - A new insight about molecular aspects of CoQ deficiency
|-
|-
|12:00 - 12:15: Marta Luna-Sánchez (Granada)
|12:00 - 12:15
CoQ deficiency: molecular and pathophysiology consequences
|Granada
|Marta Luna-Sánchez - CoQ deficiency: molecular and pathophysiology consequences
|-
|-
|12:15 - 12:30: Discussion
|12:15 - 12:30
|
|Discussion
|-
|-
|12:30: Lunch (Dining Hall)
|12:30
|Dining Hall
|Lunch 
|-
|-
|13:30: Experimental methods session (Graham Storey room)
|13:30
|Graham Storey room
|Experimental methods session  
|-
|-
|13:30 - 13:50: Vilmante Borutaite (Kaunas)
|13:30 - 13:50
How to isolate mitochondria
|Kaunas
|Vilmante Borutaite - How to isolate mitochondria
|-
|-
|13:50 - 14:10: Rodrigue Rossignol (Bordeaux)
|13:50 - 14:10
How to measure morphology, fusion/fission
|Bordeaux
|Rodrigue Rossignol - How to measure morphology, fusion/fission
|-
|-
|14:10 - 14:30: Kathrin Renner (Regensburg)
|14:10 - 14:30
How to measure respiration & membrane potential
|Regensburg
|Kathrin Renner - How to measure respiration & membrane potential
|-
|-
|14:30 - 14:50: Erich Gnaiger (Innsbruck)
|14:30 - 14:50
How to express respiratory states - www.bioblast.at
|Innsbruck
|Erich Gnaiger - How to express respiratory states - www.bioblast.at
|-
|-
|14:50 - 15:10: Chuck Hoppel (Cleveland)
|14:50 - 15:10
How to diagnose mitochondrial disease
|Cleveland
|Chuck Hoppel - How to diagnose mitochondrial disease
|-
|-
|15:10 - 15:30: Aviva Tolkovsky (Cambridge)
|15:10 - 15:30
How to measure cell death and mitophagy
|Cambridge
|Aviva Tolkovsky - How to measure cell death and mitophagy
|-
|-
|15:30 - 15:50: Mike Murphy (Cambridge)
|15:30 - 15:50
How to measure ROS
|Cambridge
|Mike Murphy - How to measure ROS
|-
|-
|15:50 - 16:00: Discussion
|15:50 - 16:00
|
|Discussion
|-
|-
|16:00: Tea break (Dining Hall)
|16:00
|Dining Hall
|Tea break  
|-
|-
|16:30: Mitochondrial coupling, thermogenesis & obesity session (Graham Storey room)
|16:30
|Graham Storey room
|Mitochondrial coupling, thermogenesis & obesity session  
|-
|-
|16:30 - 16:45:Guy Brown (Cambridge)
|16:30 - 16:45
Mitochondrial energy production
|Cambridge
|Guy Brown - Mitochondrial energy production
|-
|-
|16:45 - 17:00: Mary Ellen Harper (Ottawa)
|16:45 - 17:00
Variable mitochondrial oxidative phosphorylation efficiency and its implications for obesity
|Ottawa
|Mary Ellen Harper - Variable mitochondrial oxidative phosphorylation efficiency and its implications for obesity
|-
|-
|17:00 - 17:15: Maria Holmström (Stockholm)
|17:00 - 17:15
Tissue-specific effects of leptin treatment on mitochondrial function in obese leptin-deficient (ob/ob) mice
|Stockholm
|Maria Holmström - Tissue-specific effects of leptin treatment on mitochondrial function in obese leptin-deficient (ob/ob) mice
|-
|-
|17:15 - 17:30: Thierry Arnould (Namur)
|17:15 - 17:30
Mitochondrial uncoupling induces modifications of glucose metabolism and microRNA expression in 3T3-L1 adipocytes
|Namur
|Thierry Arnould - Mitochondrial uncoupling induces modifications of glucose metabolism and microRNA expression in 3T3-L1 adipocytes
|-
|-
|17:30 - 17:45: Erika Cortez (Rio de Janeiro)
|17:30 - 17:45
Mitochondrial oxidative metabolism impairment in bone marrow mononuclear cells of obese mice
|Rio de Janeiro
|Erika Cortez - Mitochondrial oxidative metabolism impairment in bone marrow mononuclear cells of obese mice
|-
|-
|17:45 - 18:00: Anastasia Kalinovich (Stockholm)
|17:45 - 18:00
The effects of the mitochondria-targeted cationic uncoupler C12TPP on brown adipose tissue mitochondria, cells & mice
|Stockholm
|Anastasia Kalinovich - The effects of the mitochondria-targeted cationic uncoupler C12TPP on brown adipose tissue mitochondria, cells & mice
|-
|-
|18:00 - 19:00: Discussion
|18:00 - 19:00
|
|Discussion
|-
|-
|19:00: Dinner (Dining Hall)
|19:00
|Dining Hall
|Dinner
|-
|-
|21:00: Evening tour of Cambridge & its pubs
|21:00
|
|Evening tour of Cambridge & its pubs
|-
|-
|}
|}


{| class="wikitable"
{|class='wikitable'
! Monday, 9th July
|-
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Monday, 9th July'''
|-
|-
|09:00: Mitophagy, neurons and neurodegenerative disease session (Graham Storey room)
|09:00
|Graham Storey room
|Mitophagy, neurons and neurodegenerative disease session  
|-
|-
|09:00 - 09:30: Aviva Tolkovsky (Cambridge)
|09:00 - 09:30
Mitophagy and neurodegeneration
|Cambridge
|Aviva Tolkovsky - Mitophagy and neurodegeneration
|-
|-
|09:30 - 10:00: Vilmante Borutaite (Kaunas)
|09:30 - 10:00
Mitochondria in ischaemic & neurodegenerative disease
|Kaunas
|Vilmante Borutaite - Mitochondria in ischaemic & neurodegenerative disease
|-
|-
|10:00 - 10:15: Subir Roy Chowdhury (Canada)
|10:00 - 10:15
Neurodegeneration in diabetes is linked to impaired AMPK signaling and mitochondrial dysfunction
|Canada
|Subir Roy Chowdhury - Neurodegeneration in diabetes is linked to impaired AMPK signaling and mitochondrial dysfunction
|-
|-
|10:15 - 10:30: Discussion
|10:15 - 10:30
|
|Discussion
|-
|-
|10:30: Coffee (Dining Hall)
|10:30
|Dining Hall
|Coffee
|-
|-
|11:00 - 11:15: Ana Carina Costa (Leicester)
|11:00 - 11:15
Mitochondrial chaperone Trap1 interacts genetically with Pink1 in Drosophila
|Leicester
|Ana Carina Costa - Mitochondrial chaperone Trap1 interacts genetically with Pink1 in Drosophila
|-
|-
|11:15 - 11:30: Carola Schiller (Frankfurt)
|11:15 - 11:30
Mitochondrial dysfunction in SY5Y cells moderately expressing human ß-amyloid
|Frankfurt
|Carola Schiller - Mitochondrial dysfunction in SY5Y cells moderately expressing human ß-amyloid
|-
|-
|11:30 - 11:45: Joanna Poulton (Oxford)
|11:30 - 11:45
Severe OPA1 mutations dysregulate mitophagy and disorganise the location of mitochondria in patients with OPA1 plus
|Oxford
|Joanna Poulton - Severe OPA1 mutations dysregulate mitophagy and disorganise the location of mitochondria in patients with OPA1 plus
|-
|-
|11:45 - 12:15: Discussion
|11:45 - 12:15
|
|Discussion
|-
|-
|12:30: Lunch (Dining Hall) or MiP Society Board Meeting (Bridgetower room)
|12:30
|Dining Hall
|Lunch - or MiP Society Board Meeting (Bridgetower room)
|-
|-
|13:30 - 15:00: Walk to Grantchester (meet outside Graham Storey room)
|13:30 - 15:00
|meet outside Graham Storey room
|Walk to Grantchester
|-
|-
|15:00 - 16:00: Special interest discussion sessions in Orchard Tea Gardens or The Green Man
|15:00 - 16:00
Structure & dynamics or Mitophagy & Neurodegeneration or Obesity & Coupling or Respiratory function
|in Orchard Tea Gardens
|Special interest discussion sessions or The Green Man - Structure & dynamics or Mitophagy & Neurodegeneration or Obesity & Coupling or Respiratory function
|-
|-
|16:00 - 17:00: Walk back to Cambridge
|16:00 - 17:00
|
|Walk back to Cambridge
|-
|-
|17:30: Reactive oxygen species session (Graham Storey room)
|17:30
|Graham Storey room
|Reactive oxygen species session  
|-
|-
|17:30 - 18:00: Michael Murphy (Cambridge MBU)
|17:30 - 18:00
Targeting bioactive molecules to mitochondria
|Cambridge MBU
|Michael Murphy - Targeting bioactive molecules to mitochondria
|-
|-
|18:00 - 18:15: Heather Wilkins (Denver)
|18:00 - 18:15
Dicarboxylate carrier-mediated transport of glutathione into mitochondria determines neuronal susceptibility to oxidative and nitrosative stress
|Denver
|Heather Wilkins - Dicarboxylate carrier-mediated transport of glutathione into mitochondria determines neuronal susceptibility to oxidative and nitrosative stress
|-
|-
|18:15 - 18:30: Maria Chiara Magnifico (Rome)
|18:15 - 18:30
Cell bioenergetics, nitric oxide and melatonin  
|Rome
|Maria Chiara Magnifico - Cell bioenergetics, nitric oxide and melatonin  
|-
|-
|18:30 - 18:45: Stephanie Hagl (Frankfurt)
|18:30 - 18:45
Herbal antioxidants induce mitogenesis and improve mitochondrial function in PC12 cells
|Frankfurt
|Stephanie Hagl - Herbal antioxidants induce mitogenesis and improve mitochondrial function in PC12 cells
|-
|-
|18:45 - 19:00: Ryan Mailloux (Ottawa)
|18:45 - 19:00
Glutaredoxin-2 and glutathionylation in the regulation of mitochondrial energetics in mice
|Ottawa
|Ryan Mailloux - Glutaredoxin-2 and glutathionylation in the regulation of mitochondrial energetics in mice
|-
|-
|19:00 - 19:30: Discussion
|19:00 - 19:30
|
|Discussion
|-
|-
|19:30: Dinner (Dining Hall)
|19:30
|Dining Hall
|Dinner
|-
|-
|21:00 - 22:00: Poster session (Bar & Crescent room)
|21:00 - 22:00
|Bar & Crescent room
|Poster session
|-
|-
|}
|}


{| class="wikitable"
{|class='wikitable'
! Tuesday, 10th July
|-
|-
|09:00: MRC Mitochondrial Biology Unit (Graham Storey room)
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Tuesday, 10th July'''
|-
|-
|09:00 - 09:40: Sir John Walker (Cambridge MBU)
|09:00
The ATP synthase
|Graham Storey room
|MRC Mitochondrial Biology Unit
|-
|-
|09:40 - 10:20: Leonid Sazonov (Cambridge MBU)
|09:00 - 09:40
Mitochondrial Complex I
|Cambridge MBU
|Sir John Walker - The ATP synthase
|-
|-
|10:20: Coffee break (Dining Hall)
|09:40 - 10:20
|Cambridge MBU
|Leonid Sazonov - Mitochondrial Complex I
|-
|-
|10:50 - 11:30: Edmund Kunji (Cambridge MBU)
|10:20
Mitochondrial transport proteins
|Dining Hall
|Coffee break
|-
|-
|11:30 - 12:10: Michal Minczuk (Cambridge MBU)
|10:50 - 11:30
Posttranscriptional regulation of mtDNA expression
|Cambridge MBU
|Edmund Kunji - Mitochondrial transport proteins
|-
|-
|12:10 - 12:50: Antonella Spinazzola (Cambridge MBU)
|11:30 - 12:10
Mitochondrial nucleiods and biogenesis
|Cambridge MBU
|Michal Minczuk - Posttranscriptional regulation of mtDNA expression
|-
|-
|13:00: Lunch (Dining Hall)
|12:10 - 12:50
|Cambridge MBU
|Antonella Spinazzola - Mitochondrial nucleiods and biogenesis
|-
|-
|14:00: Hypoxia, stress and exercise session (Graham Storey room)
|13:00
|Dining Hall
|Lunch
|-
|-
|14:00 - 14:30: Steve Hand (Baton Rouge)
|14:00
Mitochondrial function in an invertebrate extremophile
|Graham Storey room
|Hypoxia, stress and exercise session
|-
|-
|14:30 - 15:00: Andrew Murray (Cambridge)
|14:00 - 14:30
Mitochondria in hypoxia, exercise and altitude
|Baton Rouge
|Steve Hand - Mitochondrial function in an invertebrate extremophile
|-
|-
|15:00 - 15:15: Matthias Elstner (Munich)
|14:30 - 15:00
Life is not a sprint, it's a marathon: the metabolic gene expression footprint of human muscle fibres
|Cambridge
|Andrew Murray - Mitochondria in hypoxia, exercise and altitude
|-
|-
|15:15 - 15:30: Cesare Granata (Melbourne)
|15:00 - 15:15
Mitochondrial adaptations to different training stimuli: the remarkable plasticity of skeletal muscle oxidative capacity
|Munich
|Matthias Elstner - Life is not a sprint, it's a marathon: the metabolic gene expression footprint of human muscle fibres
|-
|-
|15:30 - 15:45: Dita Kasparova (Prague)
|15:15 - 15:30
Expression of mitochondrial creatine kinase and hexokinase is amplified in the rat heart adapted to chronic hypoxia
|Melbourne
|Cesare Granata - Mitochondrial adaptations to different training stimuli: the remarkable plasticity of skeletal muscle oxidative capacity
|-
|-
|15:45 - 16:15: Discussion
|15:30 - 15:45
|Prague
|Dita Kasparova - Expression of mitochondrial creatine kinase and hexokinase is amplified in the rat heart adapted to chronic hypoxia
|-
|-
|16:15: Tea break (Dining Hall)
|15:45 - 16:15
|
|Discussion
|-
|-
|17:15 - 19:15: Meet the PI session (Graham Storey room) 10 min 1 to 1 with the PIs of your choice
|16:15
|Dining Hall
|Tea break
|-
|-
|19:30: Dinner (Dining Hall)
|17:15 - 19:15
|Graham Storey room
|Meet the PI session - 10 min 1 to 1 with the PIs of your choice
|-
|-
|21:00 - 22:00: Poster session (Bar & Crescent room)
|19:30
|Dining Hall
|Dinner
|-
|21:00 - 22:00
|Bar & Crescent room
|Poster session
|-
|-
|}
|}


{| class="wikitable"
 
! Wednesday, 11th July
{|class='wikitable'
|-
|-
|09:00: Cancer, Sepsis & Immunity session (Graham Storey room)
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Wednesday, 11th July'''
|-
|-
|09:00 - 09:30: Rodrigue Rossignol (Bordeaux)
|09:00
Mitochondria and cancer
|Graham Storey room
|Cancer, Sepsis & Immunity session
|-
|-
|09:30 - 10:00: Elizabeth Murchison (Cambridge)
|09:00 - 09:30
The devil's mitochondria: biology and evolution of transmissible cancers
|Bordeaux
|Rodrigue Rossignol - Mitochondria and cancer
|-
|-
|10:00 - 10:15: Martina Bajzíková (Prague)
|09:30 - 10:00
Mitochondrial targeting of vitamin E succinate enhances its anti-cancer activity via mitochondrial Complex II
|Cambridge
|Elizabeth Murchison - The devil's mitochondria: biology and evolution of transmissible cancers
|-
|-
|10:15 - 10:30: Discussion
|10:00 - 10:15
|Prague
|Martina Bajzíková - Mitochondrial targeting of vitamin E succinate enhances its anti-cancer activity via mitochondrial Complex II
|-
|-
|10:30: Coffee break (Dining Hall)
|10:15 - 10:30
|
|Discussion
|-
|-
|11:00 - 11:30: Mervyn Singer (London)
|10:30
Mitochondria and sepsis
|Dining Hall
|Coffee break
|-
|-
|11:30 - 11:45: Marco Fischer (Basel)
|11:00 - 11:30
Metabolic profiles of human naïve and memory CD8+ T cells
|London
|Mervyn Singer - Mitochondria and sepsis
|-
|-
|11:45 - 12:15: Discussion
|11:30 - 11:45
|Basel
|Marco Fischer - Metabolic profiles of human naïve and memory CD8+ T cells
|-
|-
|12:30: Lunch (Dining Hall)
|11:45 - 12:15
|
|Discussion
|-
|-
|13:30 - 14:30: Special interest group discussion sessions (meet Graham Storey room)
|12:30
Modelling & regulation or Pathology or Reactive Oxygen Species or Hypoxia & Exercise & Mitochondrial DNA & disease or Cell death & the heart
|Dining Hall
|Lunch
|-
|-
|14:30 - 15:30: Punting session
|13:30 - 14:30
|Graham Storey room
|Special interest group discussion sessions - Modelling & regulation or Pathology or Reactive Oxygen Species or Hypoxia & Exercise & Mitochondrial DNA & disease or Cell death & the heart
|-
|-
|15:30: Tea break (Dining Hall)
|14:30 - 15:30
|
|Punting session
|-
|-
|16:00: Mitochondrial modelling & regulation of energy metabolism session (Graham Storey room)
|15:30
|Dining Hall
|Tea break
|-
|-
|16:00 - 16:30: Bernard Korzeniewski (Krakow)
|16:00
Computer modelling of metabolic systems
|Graham Storey room
|Mitochondrial modelling & regulation of energy metabolism session
|-
|-
|16:30 - 17:00: Alan Robinson (Cambridge MBU)
|16:00 - 16:30
Modelling the metabolism of the mitochondrion
|Krakow
|Bernard Korzeniewski - Computer modelling of metabolic systems
|-
|-
|17:00 - 17:30: Chris Cooper (Essex)
|16:30 - 17:00
Cytochrome oxidase and its modelling
|Cambridge MBU
|Alan Robinson - Modelling the metabolism of the mitochondrion
|-
|-
|17:30 - 17:45: Vitaly Selivanov (Barcelona)
|17:00 - 17:30
Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis
|Essex
|Chris Cooper - Cytochrome oxidase and its modelling
|-
|-
|17:45 - 18:00: Chong Kiat Goo (Singapore)
|17:30 - 17:45
PI3K/Akt signaling enhances mitochondrial respiratory capacity through 4E-BP1
|Barcelona
|Vitaly Selivanov - Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis
|-
|-
|18:00 - 18:15: Robert Boushel (Copenhagen)
|17:45 - 18:00
Inhibition of skeletal muscle ATPase activity alters mitochondrial substrate and adenylate control of OXPHOS, uncoupling
|Singapore
|Chong Kiat Goo - PI3K/Akt signaling enhances mitochondrial respiratory capacity through 4E-BP1
|-
|-
|18:15 - 18:30: Philippe Diolez (Bordeaux)
|18:00 - 18:15
From in vivo to in vitro: top-down control analyses of mitochondrial bioenergetics impairment in aged rat gastrocnemius muscle
|Copenhagen
|Robert Boushel - Inhibition of skeletal muscle ATPase activity alters mitochondrial substrate and adenylate control of OXPHOS, uncoupling
|-
|-
|18:30 - 19:00: Discussion
|18:15 - 18:30
|Bordeaux
|Philippe Diolez - From in vivo to in vitro: top-down control analyses of mitochondrial bioenergetics impairment in aged rat gastrocnemius muscle
|-
|-
|19:30: Dinner (Dining Hall)
|18:30 - 19:00
|
|Discussion
|-
|-
|21:00 - 22:00: Poster session (Bar & Crescent room)
|19:30
|Dining Hall
|Dinner
|-
|21:00 - 22:00
|Bar & Crescent room
|Poster session
|-
|-
|}
|}


{| class="wikitable"
{|class='wikitable'
! Thursday, 12th July
|-
|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Thursday, 12th July''' 
|-
|-
|09:00: Mitochondrial cell death, pathology & the heart session (Graham Storey room)
|09:00
|Graham Storey room
|Mitochondrial cell death, pathology & the heart session  
|-
|-
|09:00 - 09:15: Guy Brown (Cambridge)
|09:00 - 09:15
Cell death pathways
|Cambridge
|Guy Brown - Cell death pathways
|-
|-
|09:15 - 09:45: Michael Duchen (London)
|09:15 - 09:45
Mitochondrial pathology  
|London
|Michael Duchen - Mitochondrial pathology  
|-
|-
|09:45 - 10:15: Andrew Halestrap (Bristol)
|09:45 - 10:15
Mechanisms regulating ROS production and the permeability transition pore in ischaemia/reperfusion injury of the heart
|Bristol
|Andrew Halestrap - Mechanisms regulating ROS production and the permeability transition pore in ischaemia/reperfusion injury of the heart
|-
|-
|10:15 - 10:45: Discussion
|10:15 - 10:45
|
|Discussion
|-
|-
|10:45: Coffee break
|10:45
|
|Coffee break
|-
|-
|11:15 - 11:30: Marina Makrecka (Riga, Latvia)
|11:15 - 11:30
Reduced availability of L-carnitine protects cardiac mitochondria against fatty acid-induced stress
|Riga, Latvia
|Marina Makrecka - Reduced availability of L-carnitine protects cardiac mitochondria against fatty acid-induced stress
|-
|-
|11:30 - 11:45: Magdaléna Vondrusová (Prague, Czeck)
|11:30 - 11:45
The role of mitochondrial supercomplexes in apoptosis induction by mitochondria-targeted agents
|Prague, Czeck
|Magdaléna Vondrusová - The role of mitochondrial supercomplexes in apoptosis induction by mitochondria-targeted agents
|-
|-
|11:45 - 12:00: Petra Arnostova (Prague)
|11:45 - 12:00
Comparison of hexokinase expression in the left and right ventricle of male Wistar rats
|Prague
|Petra Arnostova - Comparison of hexokinase expression in the left and right ventricle of male Wistar rats
|-
|-
|12:10 - 12:30: Discussion
|12:10 - 12:30
|
|Discussion
|-
|-
|12:30: Lunch (Dining Hall)
|12:30
|Dining Hall
|Lunch 
|-
|-
|13:30 - 14:30: Punting session
|13:30 - 14:30
|
|Punting session
|-
|-
|14:30 - 15:30: The Great Debate session (Graham Storey room) The future of mitochondrial research
|14:30 - 15:30
|Graham Storey room
|The Great Debate session - The future of mitochondrial research
|-
|-
|15:30: Tea break (Dining Hall)
|15:30
|Dining Hall
|Tea break  
|-
|-
|16:00: Mitochondrial evolution, DNA & disease session (Graham Storey room)
|16:00
|Graham Storey room
|Mitochondrial evolution, DNA & disease session  
|-
|-
|16:00 - 16:30: Nick Lane (London)
|16:00 - 16:30
Mitochondria in the evolution of complex life
|London
|Nick Lane - Mitochondria in the evolution of complex life
|-
|-
|16:30 - 17:00: Masashi Tanaka (Tokyo)
|16:30 - 17:00
Rapid genetic diagnosis and pyruvate therapy for mitochondrial diseases
|Tokyo
|Masashi Tanaka - Rapid genetic diagnosis and pyruvate therapy for mitochondrial diseases
|-
|-
|17:00 - 17:15: Chin San Liu (Taiwan)
|17:00 - 17:15
Functional recovery in human cells harboring MERRF A8344G mutation of mitochondrial DNA via peptide-mediated mitochondrial delivery
|Taiwan
|Chin San Liu - Functional recovery in human cells harboring MERRF A8344G mutation of mitochondrial DNA via peptide-mediated mitochondrial delivery
|-
|-
|17:15 - 17:30: Sarah Miles (Bristol)
|17:15 - 17:30
Effect of DNA lesions on transcription by human mitochondrial RNA polymerase
|Bristol
|Sarah Miles - Effect of DNA lesions on transcription by human mitochondrial RNA polymerase
|-
|-
|-17:30 - 18:00: Discussion
|-17:30 - 18:00
|
|Discussion
|-
|-
|18:00 - 18:30: Summary - feedback - evaluation (Graham Storey room)
|18:00 - 18:30
|Graham Storey room
|Summary - feedback - evaluation  
|-
|-
|18:30 - 19:30: Reception & MiPArt exhibition (Graham Storey room &/or outside)
|18:30 - 19:30
|Graham Storey room &/or outside
|Reception & MiPArt exhibition
|-
|-
|19:30: MiP Summer Dinner (Dining Hall)
|19:30
|Dining Hall
|MiP ''Summer'' Dinner  
|-
|-
|21:00: MiP special lecture: Chris Cooper
|21:00
The Mitochondrial Olympics (Dining Hall)
|Dining Hall
|MiP special lecture: Chris Cooper - The Mitochondrial Olympics  
|-
|-
|}
|}


::::'''Friday, 13th July Departure'''
::::'''Friday, 13th July Departure'''

Latest revision as of 11:58, 27 February 2017

MiPsummer Programme

FEBS workshop & MiPsummer School on Mitochondria at Cambridge 2012
Saturday, 7th July Arrival
17:00 Bridgetower room Registration
20:00 - 20:15 Lecture theatre Welcome to Cambridge
20:15 - 21:15 Cleveland Chuck Hoppel - Mitochondrial physiology and functional testing in diagnosis of mitochondrial disease (Lecture theatre)
21:15 Terrace room Reception
Sunday, 8th July
09:00 Graham Storey room Mitochondrial structure and respiratory function session
09:00 - 09:30 Innsbruck Erich Gnaiger - Mitochondrial respiration: in vitro to in vivo
09:30 - 10:00 Bordeaux Rodrigue Rossignol - Mitochondrial structure, fission and networks
10:00 - 10:15 Baton Rouge Steve Hand - Protein targeting and translocation into mitochondria
10:15 - 10:30 Discussion
10:30 Dining Hall Coffee break
11:00 - 11:15 Gothenburg Shijun Xu - Mitochondrial dynamics at single cell level
11:15 - 11:30 NIH Kel Sheldon - VDAC blockage by tubulin is the missing link of mitochondrial respiration control
11:30 - 11:45 Nijmegen Marleen Forkink - Inhibiting mitochondrial Complex I or Complex III differentially affects mitochondrial physiology
11:45 - 12:00 Granada Laura García Corzo - A new insight about molecular aspects of CoQ deficiency
12:00 - 12:15 Granada Marta Luna-Sánchez - CoQ deficiency: molecular and pathophysiology consequences
12:15 - 12:30 Discussion
12:30 Dining Hall Lunch
13:30 Graham Storey room Experimental methods session
13:30 - 13:50 Kaunas Vilmante Borutaite - How to isolate mitochondria
13:50 - 14:10 Bordeaux Rodrigue Rossignol - How to measure morphology, fusion/fission
14:10 - 14:30 Regensburg Kathrin Renner - How to measure respiration & membrane potential
14:30 - 14:50 Innsbruck Erich Gnaiger - How to express respiratory states - www.bioblast.at
14:50 - 15:10 Cleveland Chuck Hoppel - How to diagnose mitochondrial disease
15:10 - 15:30 Cambridge Aviva Tolkovsky - How to measure cell death and mitophagy
15:30 - 15:50 Cambridge Mike Murphy - How to measure ROS
15:50 - 16:00 Discussion
16:00 Dining Hall Tea break
16:30 Graham Storey room Mitochondrial coupling, thermogenesis & obesity session
16:30 - 16:45 Cambridge Guy Brown - Mitochondrial energy production
16:45 - 17:00 Ottawa Mary Ellen Harper - Variable mitochondrial oxidative phosphorylation efficiency and its implications for obesity
17:00 - 17:15 Stockholm Maria Holmström - Tissue-specific effects of leptin treatment on mitochondrial function in obese leptin-deficient (ob/ob) mice
17:15 - 17:30 Namur Thierry Arnould - Mitochondrial uncoupling induces modifications of glucose metabolism and microRNA expression in 3T3-L1 adipocytes
17:30 - 17:45 Rio de Janeiro Erika Cortez - Mitochondrial oxidative metabolism impairment in bone marrow mononuclear cells of obese mice
17:45 - 18:00 Stockholm Anastasia Kalinovich - The effects of the mitochondria-targeted cationic uncoupler C12TPP on brown adipose tissue mitochondria, cells & mice
18:00 - 19:00 Discussion
19:00 Dining Hall Dinner
21:00 Evening tour of Cambridge & its pubs
Monday, 9th July
09:00 Graham Storey room Mitophagy, neurons and neurodegenerative disease session
09:00 - 09:30 Cambridge Aviva Tolkovsky - Mitophagy and neurodegeneration
09:30 - 10:00 Kaunas Vilmante Borutaite - Mitochondria in ischaemic & neurodegenerative disease
10:00 - 10:15 Canada Subir Roy Chowdhury - Neurodegeneration in diabetes is linked to impaired AMPK signaling and mitochondrial dysfunction
10:15 - 10:30 Discussion
10:30 Dining Hall Coffee
11:00 - 11:15 Leicester Ana Carina Costa - Mitochondrial chaperone Trap1 interacts genetically with Pink1 in Drosophila
11:15 - 11:30 Frankfurt Carola Schiller - Mitochondrial dysfunction in SY5Y cells moderately expressing human ß-amyloid
11:30 - 11:45 Oxford Joanna Poulton - Severe OPA1 mutations dysregulate mitophagy and disorganise the location of mitochondria in patients with OPA1 plus
11:45 - 12:15 Discussion
12:30 Dining Hall Lunch - or MiP Society Board Meeting (Bridgetower room)
13:30 - 15:00 meet outside Graham Storey room Walk to Grantchester
15:00 - 16:00 in Orchard Tea Gardens Special interest discussion sessions or The Green Man - Structure & dynamics or Mitophagy & Neurodegeneration or Obesity & Coupling or Respiratory function
16:00 - 17:00 Walk back to Cambridge
17:30 Graham Storey room Reactive oxygen species session
17:30 - 18:00 Cambridge MBU Michael Murphy - Targeting bioactive molecules to mitochondria
18:00 - 18:15 Denver Heather Wilkins - Dicarboxylate carrier-mediated transport of glutathione into mitochondria determines neuronal susceptibility to oxidative and nitrosative stress
18:15 - 18:30 Rome Maria Chiara Magnifico - Cell bioenergetics, nitric oxide and melatonin
18:30 - 18:45 Frankfurt Stephanie Hagl - Herbal antioxidants induce mitogenesis and improve mitochondrial function in PC12 cells
18:45 - 19:00 Ottawa Ryan Mailloux - Glutaredoxin-2 and glutathionylation in the regulation of mitochondrial energetics in mice
19:00 - 19:30 Discussion
19:30 Dining Hall Dinner
21:00 - 22:00 Bar & Crescent room Poster session
Tuesday, 10th July
09:00 Graham Storey room MRC Mitochondrial Biology Unit
09:00 - 09:40 Cambridge MBU Sir John Walker - The ATP synthase
09:40 - 10:20 Cambridge MBU Leonid Sazonov - Mitochondrial Complex I
10:20 Dining Hall Coffee break
10:50 - 11:30 Cambridge MBU Edmund Kunji - Mitochondrial transport proteins
11:30 - 12:10 Cambridge MBU Michal Minczuk - Posttranscriptional regulation of mtDNA expression
12:10 - 12:50 Cambridge MBU Antonella Spinazzola - Mitochondrial nucleiods and biogenesis
13:00 Dining Hall Lunch
14:00 Graham Storey room Hypoxia, stress and exercise session
14:00 - 14:30 Baton Rouge Steve Hand - Mitochondrial function in an invertebrate extremophile
14:30 - 15:00 Cambridge Andrew Murray - Mitochondria in hypoxia, exercise and altitude
15:00 - 15:15 Munich Matthias Elstner - Life is not a sprint, it's a marathon: the metabolic gene expression footprint of human muscle fibres
15:15 - 15:30 Melbourne Cesare Granata - Mitochondrial adaptations to different training stimuli: the remarkable plasticity of skeletal muscle oxidative capacity
15:30 - 15:45 Prague Dita Kasparova - Expression of mitochondrial creatine kinase and hexokinase is amplified in the rat heart adapted to chronic hypoxia
15:45 - 16:15 Discussion
16:15 Dining Hall Tea break
17:15 - 19:15 Graham Storey room Meet the PI session - 10 min 1 to 1 with the PIs of your choice
19:30 Dining Hall Dinner
21:00 - 22:00 Bar & Crescent room Poster session


Wednesday, 11th July
09:00 Graham Storey room Cancer, Sepsis & Immunity session
09:00 - 09:30 Bordeaux Rodrigue Rossignol - Mitochondria and cancer
09:30 - 10:00 Cambridge Elizabeth Murchison - The devil's mitochondria: biology and evolution of transmissible cancers
10:00 - 10:15 Prague Martina Bajzíková - Mitochondrial targeting of vitamin E succinate enhances its anti-cancer activity via mitochondrial Complex II
10:15 - 10:30 Discussion
10:30 Dining Hall Coffee break
11:00 - 11:30 London Mervyn Singer - Mitochondria and sepsis
11:30 - 11:45 Basel Marco Fischer - Metabolic profiles of human naïve and memory CD8+ T cells
11:45 - 12:15 Discussion
12:30 Dining Hall Lunch
13:30 - 14:30 Graham Storey room Special interest group discussion sessions - Modelling & regulation or Pathology or Reactive Oxygen Species or Hypoxia & Exercise & Mitochondrial DNA & disease or Cell death & the heart
14:30 - 15:30 Punting session
15:30 Dining Hall Tea break
16:00 Graham Storey room Mitochondrial modelling & regulation of energy metabolism session
16:00 - 16:30 Krakow Bernard Korzeniewski - Computer modelling of metabolic systems
16:30 - 17:00 Cambridge MBU Alan Robinson - Modelling the metabolism of the mitochondrion
17:00 - 17:30 Essex Chris Cooper - Cytochrome oxidase and its modelling
17:30 - 17:45 Barcelona Vitaly Selivanov - Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis
17:45 - 18:00 Singapore Chong Kiat Goo - PI3K/Akt signaling enhances mitochondrial respiratory capacity through 4E-BP1
18:00 - 18:15 Copenhagen Robert Boushel - Inhibition of skeletal muscle ATPase activity alters mitochondrial substrate and adenylate control of OXPHOS, uncoupling
18:15 - 18:30 Bordeaux Philippe Diolez - From in vivo to in vitro: top-down control analyses of mitochondrial bioenergetics impairment in aged rat gastrocnemius muscle
18:30 - 19:00 Discussion
19:30 Dining Hall Dinner
21:00 - 22:00 Bar & Crescent room Poster session
Thursday, 12th July
09:00 Graham Storey room Mitochondrial cell death, pathology & the heart session
09:00 - 09:15 Cambridge Guy Brown - Cell death pathways
09:15 - 09:45 London Michael Duchen - Mitochondrial pathology
09:45 - 10:15 Bristol Andrew Halestrap - Mechanisms regulating ROS production and the permeability transition pore in ischaemia/reperfusion injury of the heart
10:15 - 10:45 Discussion
10:45 Coffee break
11:15 - 11:30 Riga, Latvia Marina Makrecka - Reduced availability of L-carnitine protects cardiac mitochondria against fatty acid-induced stress
11:30 - 11:45 Prague, Czeck Magdaléna Vondrusová - The role of mitochondrial supercomplexes in apoptosis induction by mitochondria-targeted agents
11:45 - 12:00 Prague Petra Arnostova - Comparison of hexokinase expression in the left and right ventricle of male Wistar rats
12:10 - 12:30 Discussion
12:30 Dining Hall Lunch
13:30 - 14:30 Punting session
14:30 - 15:30 Graham Storey room The Great Debate session - The future of mitochondrial research
15:30 Dining Hall Tea break
16:00 Graham Storey room Mitochondrial evolution, DNA & disease session
16:00 - 16:30 London Nick Lane - Mitochondria in the evolution of complex life
16:30 - 17:00 Tokyo Masashi Tanaka - Rapid genetic diagnosis and pyruvate therapy for mitochondrial diseases
17:00 - 17:15 Taiwan Chin San Liu - Functional recovery in human cells harboring MERRF A8344G mutation of mitochondrial DNA via peptide-mediated mitochondrial delivery
17:15 - 17:30 Bristol Sarah Miles - Effect of DNA lesions on transcription by human mitochondrial RNA polymerase
Discussion
18:00 - 18:30 Graham Storey room Summary - feedback - evaluation
18:30 - 19:30 Graham Storey room &/or outside Reception & MiPArt exhibition
19:30 Dining Hall MiP Summer Dinner
21:00 Dining Hall MiP special lecture: Chris Cooper - The Mitochondrial Olympics
Friday, 13th July Departure
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