From Bioblast
O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (363 entries) 363 516 2 Exercise physiology;nutrition;life style 756 1050 3 Comparative MiP;environmental MiP 325 477 4 Pharmacology;toxicology 845 1042 5 mt-Biogenesis;mt-density 248 331 6 Genetic knockout;overexpression 657 727 7 Instruments;methods 273 416
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 276 418 2 Alzheimer's 71 94 3 Autism 7 11 4 Cancer 356 514 5 Cardiovascular 208 290 6 COPD 10 13 7 Diabetes 350 468 8 Inherited 64 99 9 Infectious 50 69 10 Myopathy 78 90 11 Neurodegenerative 169 235 12 Obesity 256 424 13 Parkinson's 68 105 14 Sepsis 74 85 15 Other 292 364
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 93 156 2 Cryopreservation 41 67 3 Hypoxia 117 229 4 Ischemia-reperfusion 327 434 5 Oxidative stress;RONS 583 841 6 Permeability transition 71 96 7 Temperature: hypothermia; hyperthermia 92 113
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 5 7 2 Zebrafish (» Fishes) 16 23 3 Drosophila (» Hexapods) 65 91 4 Caenorhabditis elegans (» Nematodes) 24 33 5 Artemia (» Crustaceans) 12 19 6 Saccharomyces cerevisiae (» Fungi) 61 88 7 Comparative MiP 325 477
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 15 27 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 13 18 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 116 153 5 Hexapods insects, springtails; » Drosophila 34 43 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 40 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 25 42 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 21 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 52 63 12 Plants 29 58 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 43 60 14 Eubacteria true bacteria, cyanobacteria, spirochetes 25 51 15 Archaea archaebacteria 0 7
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 188 263 2 Genital 92 123 3 Heart 725 937 4 Kidney 150 183 5 Liver 646 841 6 Lung;Gill 59 82 7 Nervous system 606 732 8 Skeletal muscle 1106 1370
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 254 320 2 Endothelial;epithelial;mesothelial cell 259 294 3 Fibroblast 207 271 4 Islet cell;pancreas;thymus 55 67 5 Leukemia 22 25 6 Lymphocyte 58 76 7 Platelet 121 151 8 Stem cells 36 48
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 14 16 2 HEK 95 116 3 HeLa 38 55 4 Neuroblastoma 43 50 5 HUVEC 19 22 6 Macrophage-derived cell lines 26 37 7 Other cells and cell lines 292 338
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 53 248 2 Intact organ 23 38 3 Living cells 1165 1314 4 Permeabilized cells 716 754 5 Permeabilized tissue 1115 1209 6 Homogenate 377 421 7 Isolated mitochondria 1265 1572 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 2 10 10 Enzyme 39 102 11 Oxidase and biochemical oxidation 39 49
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 27 2 Complex I CI 461 607 3 Complex II;succinate dehydrogenase CII 412 639 4 Complex III CIII 301 363 5 Complex IV;cytochrome c oxidase CIV 408 499 6 Complex V;ATP synthase CV 220 267 7 mt-Inner membrane transporter 31 44 8 Marker enzyme 58 84 9 Supercomplex 49 78 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 82 109 11 Uncoupling protein 60 66
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 152 209 2 ATP production 78 123 3 Aerobic glycolysis 49 94 4 Amino acid 9 20 5 Calcium 106 179 6 Coupling efficiency;uncoupling 82 163 7 Cyt c Cytochrome c 42 56 8 Fatty acid FA substrate kinetics 127 159 9 Flux control 54 86 10 Inhibitor Inhibitor kinetics 132 170 11 Ion;substrate transport 65 116 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
118 181 13 Oxygen kinetics 107 148 14 Q-junction effect 13 56 15 Redox state 58 98 16 Substrate Fuel substrate kinetics 181 236 17 Temperature Temperature dependence 73 100 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 55 70
Coupling control states
# O2k-Publications MitoPedia: Coupling control states Comment O2k Total 1 P OXPHOS capacity Oxidative phosphorylation capacity, saturating [ADP] 2870 3099 2 R ROUTINE respiration Physiological state, living cells 894 981 3 E ET-capacity Maximal noncoupled respiration 2068 2179 4 L LEAK respiration Resting state, non-phosphorylating respiration 2614 2773
Pathway control states
# O2k-Publications MitoPedia: Electron transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 610 754 2 N N-pathway control state NADH-linked, level 4 2478 2626 3 S S-pathway control state Succinate-linked, level 3 1689 1797 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 157 183 5 DQ Duorquinol-linked, level 2 26 31 6 CIV Complex IV single step Ascorbate & TMPD, level 1 702 730 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1581 1638 8 Other 133 149 9 ROX Residual oxygen consumption includes non-mitochondrial respiration 1522 1574
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1106 1370 2 O2k-Publications: Human heart 725 937 3 O2k-Publications: Skeletal muscle - human vs mouse 40 49
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35