Difference between revisions of "Coupling-control state"
| Line 4: | Line 4: | ||
}} | }} | ||
{{MitoPedia concepts | {{MitoPedia concepts | ||
|mitopedia concept=Respiratory state | |mitopedia concept=Respiratory state, SUIT state | ||
}} | }} | ||
{{MitoPedia methods | {{MitoPedia methods | ||
|mitopedia method=Respirometry | |mitopedia method=Respirometry | ||
}} | }} | ||
{{MitoPedia O2k and high-resolution respirometry | {{MitoPedia O2k and high-resolution respirometry}} | ||
}} | |||
{{MitoPedia topics}} | {{MitoPedia topics}} | ||
[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014: Fig. 2.4.]]]] | [[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014: Fig. 2.4.]]]] | ||
Revision as of 16:39, 13 May 2016
- high-resolution terminology - matching measurements at high-resolution
Coupling-control state
Description
Coupling control states are defined in mitochondrial preparations (isolated mitochondria, permeabilized cells, permeabilized tissues, homogenates) as LEAK, OXPHOS, and ETS states of respiration (L, P, E) in any substrate control state which is competent for electron transfer. These coupling states are induced by application of specific inhibitors of the phosphorylation system, titration of ADP and uncouplers. In intact cells, the coupling control states are LEAK, ROUTINE, and ETS states of respiration (L, R, E). Coupling control protocols induce these coupling control states sequentially at a constant substrate control state.
Reference: Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia concepts:
Respiratory state,
SUIT state
MitoPedia methods:
Respirometry
Coupling states: 
- 
Last edit: Gnaiger E, 2015-10-04
