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Difference between revisions of "Coupling-control state"

From Bioblast
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[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014: Fig. 2.4.]]]]
[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014: Fig. 2.4.]]]]
'''Coupling control states:''' [[Image:P.jpg|link=OXPHOS capacity|OXPHOS]] [[Image:R.jpg|link=ROUTINE respiration|ROUTINE]] [[Image:E.jpg|link=ETS capacity|ET capacity]] [[Image:L.jpg|link=LEAK respiration|LEAK]] - [[Image:ROX.jpg|link=Residual oxygen consumption|ROX]]
'''Coupling control states:''' [[Image:P.jpg|link=OXPHOS capacity|OXPHOS]] [[Image:R.jpg|link=ROUTINE respiration|ROUTINE]] [[Image:E.jpg|link=ET capacity|ET capacity]] [[Image:L.jpg|link=LEAK respiration|LEAK]] - [[Image:ROX.jpg|link=Residual oxygen consumption|ROX]]


Β  Communicated by [[Gnaiger E]] 2011-02-25, edited 2016-10-20.
Β  Communicated by [[Gnaiger E]] 2011-02-25, edited 2016-10-20.

Revision as of 14:31, 9 January 2018


high-resolution terminology - matching measurements at high-resolution


Coupling-control state

Description

Coupling control states are defined in mitochondrial preparations (isolated mitochondria, permeabilized cells, permeabilized tissues, homogenates) as LEAK, OXPHOS, and ET-pathway states of respiration (L, P, E) in any pathway control state which is competent for electron transfer. These coupling states are induced by application of specific inhibitors of the phosphorylation system, titration of ADP and uncouplers. In intact cells, the coupling control states are LEAK, ROUTINE, and ET-pathway states of respiration (L, R, E). Coupling control protocols induce these coupling control states sequentially at a constant Electron transfer-pathway state.

Abbreviation: CCS

Reference: Gnaiger 2009 Int J Biochem Cell Biol


MitoPedia concepts: MiP concept, Respiratory state, SUIT concept, SUIT state, Recommended 


MitoPedia methods: Respirometry 


MitoPedia topics: EAGLE 

Coupling control states: OXPHOS ROUTINE ET capacity LEAK - ROX

Communicated by Gnaiger E 2011-02-25, edited 2016-10-20.