Difference between revisions of "Glutamate-aspartate carrier"
From Bioblast
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|info=[http://www.oroboros.at/?Gnaiger_2012_MitoPathways Gnaiger 2012 MitoPathways] | |info=[http://www.oroboros.at/?Gnaiger_2012_MitoPathways Gnaiger 2012 MitoPathways] | ||
|type=Substrate ETS | |type=Substrate ETS | ||
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Revision as of 12:28, 17 May 2016
Description
The glutamate-aspartate carrier catalyzes the electrogenic antiport of glutamate- +H+ for aspartate-. It is an important component of the malate-aspartate shuttle in many mitochondria. Due to the symport of glutamate- + +H+, the glutamate-aspartate antiport is not electroneutal and may be impaired by uncoupling. Aminooxyacetate is an inhibitor of the glutamate-aspartate carrier.
Reference: Gnaiger 2012 MitoPathways
MitoPedia topics: Substrate and metabolite