Difference between revisions of "Huetter 2002 Mol Biol Rep"
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|title=Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7. | |title=Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7. | ||
|info=[http://www.ncbi.nlm.nih.gov/pubmed/12241081 PMID: 12241081] | |info=[http://www.ncbi.nlm.nih.gov/pubmed/12241081 PMID: 12241081] | ||
|authors=Huetter E, Renner K, Jansen-Duerr P, Gnaiger | |authors=Huetter E, Renner K, Jansen-Duerr P, Gnaiger Erich | ||
|year=2002 | |year=2002 | ||
|journal=Mol Biol Rep | |journal=Mol Biol Rep |
Revision as of 04:20, 23 November 2021
Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7. |
Huetter E, Renner K, Jansen-Duerr P, Gnaiger Erich (2002) Mol Biol Rep
Abstract: Oxygen kinetics in fibroblasts was biphasic. This was quantitatively explained by a major mitochondrial hyperbolic component in the low-oxygen range and a linear increase of rotenone- and antimycin A- inhibited oxygen consumption in the high-oxygen range. This suggest an increased production of reactive oxygen species and oxidative stress at elevated, air-level oxygen concentrations. The high oxygen activity of mitochondrial respiration provides the basis for the maintenance of a high aerobic scope at physiological low-oxygen levels, whereas further pronounced depression induces energetic stress under hypoxia.
• O2k-Network Lab: AT Innsbruck Gnaiger E, AT Innsbruck Jansen-Duerr P, AT Innsbruck Oroboros, DE Regensburg Renner-Sattler K
Labels: MiParea: Respiration
Organism: Human
Tissue;cell: Fibroblast
Preparation: Intact cells
Regulation: Oxygen kinetics Coupling state: ROUTINE Pathway: ROX HRR: Oxygraph-2k