Malate dehydrogenase: Difference between revisions
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|description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD<sup>+</sup> to NADH+H<sup>+</sup> in the [[TCA cycle]]. Malate is thus a C<sub>I</sub>-linked substrate. | |description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD<sup>+</sup> to NADH+H<sup>+</sup> in the [[TCA cycle]]. Malate is thus a C<sub>I</sub>-linked substrate. | ||
|info=[[Gnaiger 2014 MitoPathways]] | |info=[[Gnaiger 2014 MitoPathways]] | ||
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{{MitoPedia methods}} | |||
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|mitopedia topic=Enzyme | |||
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Revision as of 14:57, 19 July 2014
- high-resolution terminology - matching measurements at high-resolution
Malate dehydrogenase
Description
Mitochondrial malate dehydrogenase is localized in the mitochondrial matrix and oxidizes malate, generated from fumarate by fumarase, to oxaloacetate, reducing NAD+ to NADH+H+ in the TCA cycle. Malate is thus a CI-linked substrate.
Abbreviation: MDH
Reference: Gnaiger 2014 MitoPathways
MitoPedia topics: Enzyme
