MitoEAGLE data: fat

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Working Groups

Short-Term Scientific Missions

Management Committee

Members

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

MitoEAGLE data: fat

WG3

MITOEAGLE data repository on fat tissues and other tissues

Project application

WG3 Description

Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (Kraunsøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.

WG3 Management

Tasks

1. Kick-off meeting discussing mt fitness evaluated in fat tissue, future applications, consensus protocols and reporting schemes in a standardize format.
2. Collection and indexing of the data sets as required for statistical analysis.
3. Draft a comprehensive review on mt-function in adipose tissue (registration at PROSPERO, link with EQUATOR).

Milestones

1. Kick-off meeting.
2. Data sets entered in standardized format.
3. Summary, interpretation and discussion of data for review.

Deliverables

1. Guidelines for future research and recommendations for the evaluation of respiratory characteristics in fat tissue.
2. A database on mt fitness evaluated with fat tissue from humans and model organisms and post-study reports (PubMed Commons).
3. Draft of review manuscript.

WG3 Participants and task groups

WG3 Participants

Country	City	Contact
Austria	Innsbruck	Jansen-Duerr Pidder
Austria	Innsbruck	Doerrier Carolina
Austria	Innsbruck	Bergmeister Lisa
Austria	Innsbruck	Sobotka Ondrej
Austria	Innsbruck	Gnaiger Erich
Austria	Salzburg	Mayr JA
Belgium	Leuven	Bird Matthew
Belgium	Namur	Storder Julie
Belgium	Namur	Renard P
Belgium	Namur	Arnould Thierry
Brasil	Brasilia	De Bem Andreza Fabro
Brazil	Sao Paulo	Festuccia William T
Bulgaria	Stara Zagora	Georgieva T
Canada	Quebec	Joseph Vincent
Croatia	Zagreb	Curik I
Croatia	Split	Ljubkovic M
Czech Republic	Hradec Kralove	Banni Aml
Czech Republic	Hradec Kralove	Cervinkova Zuzana
Czech Republic	Hradec Kralove	Stankova Pavla
Czech Republic	Hradec Kralove	Maseko Tumisang Edward
Czech Republic	Hradec Kralove	Endlicher Rene
Czech Republic	Hradec Kralove	Nozickova Katerina
Czech Republic	Hradec Kralove	Kucera Otto
Czech Republic and Australia	Prague and Southport	Neuzil Jiri
Denmark	Copenhagen	Karavaeva Iuliia
Denmark	Copenhagen	Ma Tao
Denmark	Malov	Hey-Mogensen M
Finland	Helsinki	Pirinen E
France	Montpellier Cedex 01	Feillet Coudray C
France	Bordeaux cedex	Mourier A
Germany	Biberach an der Riß	Nold V
Germany	Ulm	Schaefer PM
Germany	Duesseldorf	Roden Michael
Germany	Freising	Fromme Tobias
Germany	Frankfurt am Main	Koenig M
Germany	Frankfurt am Main	Thinnes A
Germany	Ulm	Merz Tamara
Germany	Cologne	Pesta Dominik
Germany	Freising	Klingenspor Martin
Germany	Freising	Schoettl T
Germany	Leipzig	Ost Mario
Germany	Duesseldorf	Jelenik T
Greece	Athens	Trougakos Ioannis P
Hungary	Budapest	Tretter Laszlo
Hungary	Debrecen	Verebne Tar K
Hungary	Debrecen	Virag L
Israel	Haifa	Ene H
Israel	Haifa	Ben-Shachar Dorit
Israel	Zrifin	Sova Marina
Israel	Rishon Le Zion	Hachmo Yafit
Italy	Novara	Reano Simone
Italy	Agrigento	Di Nolfo F
Italy	Ancona	Battino Maurizio
Italy	Pisa	Gastaldelli Amalia
Italy	Padova	Ziviani E
Italy	Padova	Scorrano L
Italy	Padova	Marchesan Elena
Italy	Rome	Scatena Roberto
Italy	Bologna	Genova Maria Luisa
Italy	Padova	Giacomello M
Latvia	Riga	Bello Fiona
Lithuania	Kaunas	Arandarcikaite Odeta
Lithuania	Kaunas	Borutaite Vilma
Netherlands	Wageningen	Shi W
Netherlands	Wageningen	Keijer Jaap
Norway	Tromsoe	Jansen Kirsten M
Norway	Tromsoe	Lund T
Norway	Ullevål	Marstein H
Norway	Oslo	Eide L
Norway	Tromsoe	Schots Pauke C
Poland	Lodz	Watala Cezary
Poland	Lodz	Labieniec-Watala Magdalena
Portugal	Porto	Beleza Jorge
Portugal	Coimbra	Carvalho Eugenia
Portugal	Coimbra	Pereira Susana P
Portugal	Coimbra	Palmeira Carlos
Portugal	Porto	Coxito Pedro
Portugal	Coimbre	Jones John G
Portugal	Coimbra	Nunes Sara
Portugal	Coimbra	Dias Candida
Portugal	Porto	Magalhaes Jose
Portugal	Coimbra	Preguica Ines
Portugal	Porto	Mendes D
Portugal	Coimbra	Carvalho Cristina
Republic of Korea	Yuseong-gu Daejeon	Quang Don T
Republic of Macedonia	Stip	Ruskovska T
Serbia	Belgrad	Markovic Ivanka
Singapore	Singapore	Singh Brijesh Kumar
Slovakia	Bratislava	Sumbalova Zuzana
Spain	Madrid	Monsalve Maria
Spain	Barcelona	Gama Perez Pau
Spain	Barcelona	Arago Marc
Spain	Sevilla	Bustos Matilde
Spain	Barcelona	Dahdah Norma Ramon
Spain	Valencia	Fuertes Agudo Marina
Spain	Valencia	Casado Pinna Marta
Spain	Derio, Bizkaia. Basque Country	Martinez-Chantar ML
Spain	Barcelona	Garrabou Gloria
Spain	Bellaterra/ Barcelona	Quintana A
Spain	Barcelona	Herrero L
Spain	Madrid	Peral B
Spain	Barcelona	Perales Jose Carles
Spain	Barcelona	Sanchez Feutrie M
Spain	Barcelona	Soler Vazquez DC
Spain	Barcelona	Moren C
Spain	Barcelona	Villena Josep A
Spain	Sevilla	Muntane Jordi
Spain	Granada	Quiles JL
Spain	Barcelona	Claret M
Spain	Derio, BI	Goikoetxea Usandizaga Naroa
Spain	Barcelona	Garcia-Roves Pablo Miguel
Spain	A Coruña	Mayan MD
Spain	Barcelona	Ribeiro ML
Spain	Madrid	Moran M
Sweden	Stockholm	Cannon B
Sweden	Stockholm	Nedergaard J
Sweden	Stockholm	Shabalina Irina G
Sweden	Stockholm	Gao Yun
Switzerland	Zürich	Schneider Gasser Edith Mariane
Switzerland	Lausanne	Burtscher Johannes
Turkey	Ankara	Olgar Yusuf
Turkey	Ankara	Turan Belma
Turkey	Ankara	Degirmenci S
Turkey	Ankara	Durak A
Turkey	Ankara	Tuncay Erkan
Turkey	Ankara	Akcali KC
Turkey	Meram/Konya	Celen Murat C
USA	Boca Raton	Khamoui Andy V
USA	Winston-Salem	Tomar Dhanendra
USA	Philadelphia	Jadiya Pooja
USA	St Louis	Welch R
USA	Camden	Solesio Maria E
USA	Fairbanks	O'Brien Kristin
USA	Little Rock	Porter Craig
USA	New York	Galkin Alexander
United Kingdom	Birmingham	Garten Antje
United Kingdom	Nottingham	Chakrabarti Lisa
United Kingdom	Brighton	Moore Anthony L
United Kingdom	Leeds	Boyle JP
United Kingdom	Birmingham	Joanisse S
United Kingdom	Loughborough	Ebanks Brad

WG3 Task groups

TG3.1 Fat

TG leader: Nedergaard Jan

TG participants: Palmeira Carlos

TG3.2 Liver

TG leaders: Cervinkova Zuzana (suggested) / Sumbalova Zuzana

TG participants: Monsalve Maria, Palmeira Carlos

TG3.3 Neuronal

TG leaders: Sandi Carmen (suggested) / Borutaite Vilma (suggested)

TG participants: Watala Cezary

WG3 Comments and discussion

1. Based on your previous suggestions, with a great pleasure I will take up some managements duties, i.e. Short-Term Sicentific Missions organizations/coordinatings, and/or so on. I choose WG 4 (blood cells and culture cells) eventually also WG 3 (other tissues than fat) but this will depend on grant funds receving(s) in the near future. ... I have just read the COST evaluation form and I congratulate you this beautiful/great success!!!! This news makes me very happy and I am proud of becoming a member of this "mitochondrial family. - Magdalena Labieniec-Watala (2016).
2. Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past – in studying of the following cell /tissue types:
   1. Blood cells, with particular emphasis on platelets and lymphocytes – isolated from animals and humans.
   2. Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines – predominantly cultured.
   3. Hepatocytes, cardiomyocytes, cell isolated from brain – isolated from lab animals. - Cezary Watala (2016).
3. I have already contacted the portuguese CNC to nominate me for the MC of theaction. Concerning my active participation, taking into account the type of work we do in my lab I could be included in all WGs. As you know we work with mitochondria from liver, muscle and fat, as well as cultured cells from different origins (WG2-4). The elaboration of SOPs (WG1) we can certainly contribute (see the book I edited on Mitochondrial Bioenergetics and in which you contribute a chapter). I believe that everybody can be part of the WG5, but as the coordinators of the action, you and Sandra should decide what is best for the success of the action. - Carlos Palmeira (2016).

Projects in progress

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