MitoKit-CII MitoPedia: Difference between revisions

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{{MitoPedia
#REDIRECT [[MitoKit-CII]]
|abbr=MitoKit-CII
|description='''Cell permeable prodrugs''', composed of [[NV161/MitoKit-CII]] and [[NV118/MitoKit-CII]], of the Complex II substrate succinate increase ATP-linked mitochondrial respiration in CI-deficient human blood cells, fibroblasts and heart fibres.
|info=[[MitoKit-CII]], [[Ehinger 2016 Nat Commun]]
}}
{{MitoPedia topics
|mitopedia topic=Medium
}}
 
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== Application in [[HRR]] ==
 
 
=== Preparation ===
 
:::: Both compounds are dissolved in DMSO and stored in aliquots at -20 °C.
:::: We recommend the following dilutions for reaching the desired concentration in the experiments:
 
 
::::* NV118/MitoKit-CII: 100 mM stock solution - more details [[NV118/MitoKit-CII|here]]
::::* NV161/MitoKit-CII: 10 mM stock solution - more details [[NV161/MitoKit-CII|here]]
 
 
== SUITbrowser question: Permeable succinate/malonate ==
Work in progress

Latest revision as of 10:53, 7 December 2020

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