S/NS pathway control ratio: Difference between revisions
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|info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2014 MitoPathways]] | |info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2014 MitoPathways]] | ||
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|mitopedia | |mitopedia concept=Respiratory control ratio | ||
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= List of publications: CII and CI<small>&</small>II = | = List of publications: CII and CI<small>&</small>II = | ||
{{#ask:[[Category:Publications]] [[Substrate states::CII]] [[Substrate states::CI | {{#ask:[[Category:Publications]] [[Substrate states::CII]] [[Substrate states::CI&II]] | ||
|?Was published in year=Year | |?Was published in year=Year | ||
|?Has title=Reference | |?Has title=Reference |
Revision as of 12:51, 8 February 2016
Description
The CII/CI&II substrate control ratio is obtained when rotenone (Rot) is added to CI&II-linked respiration in a defined coupling state. The reversed protocol, adding CI-linked substrates to a CII-linked background state does not provide a valid estimation of CII-linked respiration with succinate in the absence of Rot, since oxaloacetate accumulates as a potent inhibitor of succinate dehydrogenase (CII).
Abbreviation: CII/CI&II
Reference: Gnaiger 2009 Int J Biochem Cell Biol, Gnaiger 2014 MitoPathways
MitoPedia concepts:
Respiratory control ratio