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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Xhani 2017 Thesis | 2017 | Xhani M (2017) Cellular redox homeostasis and environmental toxicity. Dissertation p110. | OXPHOS | N S CIV ROX | Permeabilized cells | Human | Liver Other cell lines |
Profilo 2017 Biochim Biophys Acta | 2017 | Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines Neuroblastoma |
Braz-Mota 2017 Thesis | 2017 | Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78. | LEAK OXPHOS ET | N NS ROX | Homogenate | Fishes | Lung;gill |
Fourcade 2017 Aging Cell | 2017 | Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A (2017) Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-13. | LEAK OXPHOS | N S NS ROX | Mouse | ||
Categories of SUIT protocols | 2017 | Gnaiger E (2017) Categories of SUIT protocols and ETS pathway control states. MiPNet 2017-03-12; original 2016-03-20; edited 2016-08-21. | F N S Gp CIV NS Other combinations ROX | ||||
Kane 2017 J Cell Mol Med | 2017 | Kane MS, Alban J, Desquiret-Dumas V, Gueguen N, Ishak L, Ferre M, Amati-Bonneau P, Procaccio V, Bonneau D, Lenaers G, Reynier P, Chevrollier A (2017) Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy. J Cell Mol Med 21:2284-97. | LEAK ET | Other combinations ROX | Intact cells | Human | Fibroblast |
Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | LEAK ROUTINE OXPHOS ET | F S CIV NS ROX | Intact cells | Blood cells | |
Kyhl 2017 Peptides | 2017 | Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12. | OXPHOS LEAK | F N S NS ROX | Permeabilized tissue | Rat | Heart |
Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | LEAK OXPHOS ET ROUTINE | N NS ROX CIV | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Paech 2017 Arch Toxicol | 2017 | Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62. | LEAK OXPHOS ET | N S DQ CIV ROX | Permeabilized cells | Human | Liver Other cell lines |
Bombaca 2017 Free Radic Biol Med | 2017 | Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66. | ROUTINE | CIV ROX | Intact cells | Protists | |
Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Saccharomyces cerevisiae Human | Lymphocyte |
Alves 2017 Free Radic Biol Med | 2017 | Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39. | LEAK ROUTINE | ROX | Rat | ||
Krylova 2017 Biomed Khim | 2017 | Krylova TD, Tsygankova PG, Itkis YS, Sheremet NL, Nevinitsyna TA, Mikhaylova SV, Zakharova EY (2017) High resolution respirometry in diagnostic of mitochondrial disorders caused by mitochondrial complex I deficiency. Biomed Khim 63:327-33. | ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Cunha 2017 Int J Biol Macromol | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Jang 2017 Biol Open | 2017 | Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9. | LEAK ROUTINE ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Lau 2017 Dissertation | 2017 | Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Fishes | Nervous system |
Michalak 2017 Oxid Med Cell Longev | 2017 | Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574. | LEAK ROUTINE ET | ROX | Intact cells | Blood cells | |
Rodolphi 2017 Thesis | 2017 | Rodolphi MS (2017) Efeitos da nandrolona e da ceftriaxona na homeostasia glutamatérgica: uma busca por mecanismos interativos entre astrócitos e neurônios envolvidos no comportamento agressivo. Dissertation p58. | ROUTINE OXPHOS | S CIV ROX | Homogenate | Mouse | Nervous system |
Lopez 2017 Sci Rep | 2017 | Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA (2017) Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. Sci Rep 7:9835. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells | Human | |
Cunha de Padua 2017 Carbohydr Polym | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75. | LEAK ROUTINE ET | ROX | Human | Liver | |
White 2017 Sci Rep | 2017 | White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Ljones 2017 PLOS ONE | 2017 | Ljones K, Ness HO, Solvang-Garten K, Gaustad SE, Andre Høydal M (2017) Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats. PLOS ONE 12:e0173449. | OXPHOS ET LEAK | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Thomas 2017 Thesis | 2017 | Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Rat | Liver |
Radenkovic 2017 Biochem Pharmacol | 2017 | Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines |
Koit 2017 Oxid Med Cell Longev | 2017 | Koit A, Shevchuk I, Ounpuu L, Klepinin A, Chekulayev V, Timohhina N, Tepp K, Puurand M,Truu L, Heck K, Valvere V, Guzun R, Kaambre T (2017) Mitochondrial respiration in human colorectal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640. | OXPHOS LEAK | N S CIV ROX NS | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Carraro 2017 Mol Cell Endocrinol | 2017 | Carraro RS, Souza GF, Solon C, Razolli DS, Chausse B, Barbizan R, Victorio SC, Velloso LA (2017) Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol 460:238-45. | LEAK OXPHOS | N ROX | Permeabilized tissue | Mouse | Nervous system |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet |
Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | LEAK ROUTINE OXPHOS | F N NS ROX | Permeabilized cells Intact cells | Skeletal muscle | |
Martins 2017 Thesis | 2017 | Martins WC (2017) Estudo do efeito protetor da atorvastatina e dos eventos iniciais da neurotoxicidade induzida pelo peptídeo β-amilóide (Aβ1-40) em camundongos. Doctoral Thesis p85. | LEAK OXPHOS ET | N NS ROX | Homogenate | Mouse | Nervous system |
Khalifa 2017 Physiol Rep | 2017 | Khalifa AR, Abdel-Rahman EA, Mahmoud AM, Ali MH, Noureldin M, Saber SH, Mohsen M, Ali SS (2017) Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep 5. pii: e13125. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Heart Nervous system |
MiPNet21.14 Reference sample HRR | 2016-10-19 | Development of a reference sample for HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet21.13 Comparison mt-preparations | 2016-10-18 | O2k-Protocols: Mitochondrial preparations for HRR. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Mouse | Heart |
MiPNet21.12 Comparison mt respiration media | 2016-10-18 | O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | HEK |
MiPNet10.04 CellRespiration | 2016-08-08 | An experiment with high-resolution respirometry: coupling control in cell respiration. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells |
MiPNet21.07 MitoFit DatLab PT | 2016-07-20 | MitoFit DatLab proficiency test. | LEAK OXPHOS ET | F N S Gp CIV Other combinations ROX | Permeabilized cells | Human | |
Ryan 2016 J Mol Cell Cardiol | 2016 | Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Salin 2016 Physiol Biochem Zool | 2016 | Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23. | LEAK OXPHOS | N CIV NS ROX | Homogenate | Fishes | Skeletal muscle Liver |
Shama 2016 Evol Appl | 2016 | Shama LNS, Mark FC, Strobel A, Lokmer A, John U, Wegner KM (2016) Transgenerational effects persist down the maternal line in marine sticklebacks: gene expression matches physiology in a warming ocean. Evol Appl 10013/epic.47323. | LEAK OXPHOS ET | NS ROX | Permeabilized tissue | Fishes | Heart |
Vevera 2016 Physiol Res | 2016 | Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88. | LEAK ROUTINE OXPHOS ET | N S NS Other combinations ROX | Intact cells Permeabilized cells | Human Rat | Blood cells Platelet |
Hals 2016 Islets | 2016 | Hals IK, Singh R, Ma Z, Scholz H, Björklund A, Grill V (2016) Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability. Islets 8:165-76. | LEAK ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
Briston 2016 Sci Rep | 2016 | Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Liver |
Chowdhury 2015 Biosci Rep | 2016 | Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Mouse | Nervous system |
Gdynia 2016 Nat Commun | 2016 | Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764. | ROUTINE | ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Watala 2016 Int J Pharm | 2016 | Watala C, Karolczak K, Kassassir H, Siewiera K, Maczynska K, Pieniazek A, Labieniec-Watala M (2016) How do the full-generation poly(amido)amine (PAMAM) dendrimers activate blood platelets? Platelet membrane zeta potential and other membrane-associated phenomena. Int J Pharm 500:379-89. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Li 2016 J Appl Physiol (1985) | 2016 | Li C, White SH, Warren LK, Wohlgemuth SE (2016) Effects of aging on mitochondrial function in skeletal muscle of quarter horses. J Appl Physiol (1985) 121:299-311. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Giraldos Jimenez 2016 Thesis | 2016 | Giraldos Jiménez D (2016) Oxidative phosphorylation system’s role in adipogenic differentiation. Thesis p25. | LEAK ROUTINE | ROX | |||
Reis 2016 Aging (Albany NY) | 2016 | Reis FC, Branquinho JL, Brandão BB, Guerra BA, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA (2016) Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany NY) 8:1201-22. | LEAK | N S ROX | Permeabilized cells | Mouse | Fat |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
Du 2016 Thesis | 2016 | Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175. | LEAK OXPHOS ET | S CIV ROX N NS | Permeabilized cells | Fishes | Liver |
Wolff 2016 J Evol Biol | 2016 | Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47. | LEAK OXPHOS ET | N Gp CIV Other combinations ROX | Permeabilized tissue | Drosophila | Skeletal muscle |
Christensen 2016 J Appl Physiol (1985) | 2016 | Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Heimer 2016 Am J Hum Genet | 2016 | Heimer G, Kerätär JM, Riley LG, Balasubramaniam S, Eyal E, Pietikäinen LP, Hiltunen JK, Marek-Yagel D, Hamada J, Gregory A, Rogers C, Hogarth P, Nance MA, Shalva N, Veber A, Tzadok M, Nissenkorn A, Tonduti D, Renaldo F, Kraoua I, Panteghini C, Valletta L, Garavaglia B, Cowley MJ, Gayevskiy V, Roscioli T, Silberstein JM, Hoffmann C, Raas-Rothschild A, Tiranti V, Anikster Y, Christodoulou J, Kastaniotis AJ, Ben-Zeev B, Hayflick SJ (2016) MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. Am J Hum Genet 99:1229-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Spendiff 2016 J Physiol | 2016 | Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT (2016) Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol 594:7361-79. | OXPHOS LEAK | N CIV NS ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
Chu 2016 World J Gastroenterol | 2016 | Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Kilbaugh 2016 Mitochondrion | 2016 | Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Smith 2016 Diabetes | 2016 | Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle Liver Fat |
Takahashi 2016 Exp Gerontol | 2016 | Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2016) Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q. Exp Gerontol 81:65-75. | OXPHOS | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Lemieux 2016 Mitochondrion | 2016 | Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Macheiner 2016 Sci Rep | 2016 | Macheiner T, Fengler VH, Agreiter M, Eisenberg T, Madeo F, Kolb D, Huppertz B, Ackbar R, Sargsyan K (2016) Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells. Sci Rep 6:35571. | LEAK ROUTINE ET | ROX | Human | Fibroblast Lung;gill | |
Leucci 2016 Nature | 2016 | Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Moll 2016 bioRxiv | 2016 | Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells Permeabilized cells | Human | Stem cells |
Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Yamada 2016 J Physiol | 2016 | Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95. | LEAK OXPHOS | N S CIV Other combinations ROX | Mouse | Skeletal muscle Other cell lines | |
Jang 2016 J Intensive Care Med | 2016 | Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Docherty 2016 Stem Cell Res Ther | 2016 | Docherty CK, Salt IP, Mercer JR (2016) Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells. Stem Cell Res Ther 7:78. | LEAK ET | ROX | Intact cells | Human | Kidney HEK |
Moon 2016 J Biol Chem | 2016 | Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700. | LEAK OXPHOS | F N S NS Other combinations ROX | Isolated mitochondria | Mouse | Heart |
Timpani 2016 Neurotherapeutics | 2016 | Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46. | LEAK OXPHOS ET | N CIV NS Other combinations ROX S | Permeabilized tissue | Mouse | Skeletal muscle |
Berschneider 2016 Thesis | 2016 | Berschneider K (2016) Connecting the functions of the proteasome and mitochondria in the lung. Dissertation p161. | LEAK ROUTINE ET | ROX | Permeabilized cells | Mouse | Lung;gill |
Berressem 2016 PLOS ONE | 2016 | Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Scialo 2016 Cell Metab | 2016 | Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A (2016) Mitochondrial ROS produced via reverse electron transport extend animal lifespan. Cell Metab 23:725-34. | LEAK OXPHOS | N Gp CIV Other combinations ROX | Homogenate | Drosophila | |
Kontro 2016 Thesis | 2016 | Kontro H (2016) Mitochondrial function and sirtuin expression in hippocampus of young and old high and low-capacity runner rats. Master's Thesis p35. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Tyrrell 2016 Redox Biol | 2016 | Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77. https://doi.org/10.1016/j.redox.2016.09.009 | OXPHOS LEAK ET | N NS ROX | Permeabilized tissue Isolated mitochondria Intact cells | Other mammals Human | Skeletal muscle Blood cells Platelet |
Hagl 2016 Nutr Neurosci | 2016 | Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Siewiera 2016 Life Sci | 2016 | Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2016) Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats. Life Sci 148:293-304. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Blood cells Platelet |
Schoenenberger 2016 Cancer Res | 2016 | Schönenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36. | OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Nervous system |
Singh 2016 Mol Neurobiol | 2016 | Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904. | LEAK | N S ROX | Isolated mitochondria | Pig | Nervous system |
Salin 2016 J Exp Biol | 2016 | Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62. | LEAK OXPHOS | N S CIV NS Other combinations ROX | Permeabilized tissue | Fishes | Skeletal muscle Liver |
McCourt 2016 PLOS ONE | 2016 | McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870. | LEAK OXPHOS ET | NS ROX | Permeabilized cells | Mouse | Fat |
Chubanov 2016 Elife | 2016 | Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T (2016) Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife 5. pii: e20914. | ROUTINE ET | ROX | Intact cells | Human | Fibroblast Other cell lines |
Hancock 2016 Amino Acids | 2016 | Hancock CN, Liu W, Alvord WG, Phang JM (2016) Co-regulation of mitochondrial respiration by proline dehydrogenase/oxidase and succinate. Amino Acids 48:859-72. | LEAK ROUTINE ET | S Other combinations ROX | Isolated mitochondria Oxidase;biochemical oxidation Intact cells | Mouse | Liver |
Villani 2016 Mol Metab | 2016 | Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56. | OXPHOS | N S ROX | Permeabilized cells | Human | Genital |
Holandino 2016 Bioelectrochemistry | 2016 | Holandino C, Teixeira CA, de Oliveira FA, Barbosa GM, Siqueira CM, Messeder DJ, de Aguiar FS, da Veiga VF, Girard-Dias W, Miranda K, Galina A, Capella MA, Morales MM (2016) Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line. Bioelectrochemistry 111:83-92. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lung;gill Other cell lines |
Dechandt 2016 Anal Biochem | 2016 | Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Rat | Fat |
Fisar 2016a Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Pig | Nervous system |
Johnson 2016 Diabetes | 2016 | Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | Skeletal muscle |
Price 2016 J Thermal Biol | 2016 | Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Reptiles | Heart Skeletal muscle |
Loureiro 2016 Oxid Med Cell Longev | 2016 | Loureiro AC, do Rêgo-Monteiro IC, Louzada RA, Ortenzi VH, de Aguiar AP, de Abreu ES, Cavalcanti-de-Albuquerque JP, Hecht F, de Oliveira AC, Ceccatto VM, Fortunato RS, Carvalho DP (2016) Differential expression of NADPH oxidases depends on skeletal muscle fiber type in rats. Oxid Med Cell Longev 2016:6738701. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Gerber 2016 J Med Genet | 2016 | Gerber S, Ding MG, Gérard X, Zwicker K, Zanlonghi X, Rio M, Serre V, Hanein S, Munnich A, Rotig A, Bianchi L, Amati-Bonneau P, Elpeleg O, Kaplan J, Brandt U, Rozet JM (2016) Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. J Med Genet 54:346-56. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Farsijani 2016 J Clin Invest | 2016 | Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37. | LEAK OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Sengupta 2016 Free Radic Biol Med | 2016 | Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA (2016) The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Lung;gill Fibroblast |
Queliconi 2016 PLOS ONE | 2016 | Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678. | LEAK OXPHOS ET | S ROX | Isolated mitochondria | Rat | Heart |
Perna 2016 Amino Acids | 2016 | Perna MK, Kokenge AN, Miles KN, Udobi KC, Clark JF, Pyne-Geithman GJ, Khuchua Z, Skelton MR (2016) Creatine transporter deficiency leads to increased whole body and cellular metabolism. Amino Acids 48:2057-65. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Cheng 2016 Nat Immunol | 2016 | Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG (2016) Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Reynolds 2016 Am J Physiol Endocrinol Metab | 2016 | Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus |
Jang 2016 Clin Toxicol (Phila) | 2016 | Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Franko 2016 Diabetes | 2016 | Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells Permeabilized tissue | Human | Skeletal muscle Fibroblast |
Ferguson 2016 J Bioenerg Biomembr | 2016 | Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Homogenate Intact cells | Pig | Nervous system Platelet |
Svenkrtova 2016 Biogerontology | 2016 | Svenkrtova A, Belicova L, Volejnikova A, Sigler K, Jazwinski SM, Pichova A (2016) Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality. Biogerontology 17:395-408. | ROUTINE | CIV ROX | Intact cells | Saccharomyces cerevisiae | |
Fonseca-Berzal 2016 Parasitology | 2016 | Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78. | ROUTINE | ROX | Intact organism | Protists |