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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Coupling-control protocol | 2015 | Gnaiger E (2015) From PCP to CCP. Mitochondr Physiol Network 2015-01-11. | LEAK ROUTINE OXPHOS ET | ||||
Tan 2015 Cell Metab | 2015 | Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines |
Blatzer 2015 Antioxid Redox Signal | 2015 | Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D (2015) Amphotericin B resistance in Aspergillus terreus is overpowered by co-application of pro-oxidants. Antioxid Redox Signal 23:1424-38. https://doi.org/10.1089/ars.2014.6220 | ROUTINE | ROX | Intact cells | Fungi | |
Ruiz-Perez 2015 J Biol Chem | 2015 | Ruiz-Pérez MV, Medina MÁ, Urdiales JL, Keinänen TA, Sánchez-Jiménez F (2015) Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells. J Biol Chem 290:6106-19. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system Other cell lines Neuroblastoma |
Truksa 2015 Antioxid Redox Signal | 2015 | Truksa J, Dong L, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J (2015) Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis. Antioxid Redox Signal 22:883-900. | ROUTINE | S | Intact cells | Human Mouse | Genital Other cell lines |
Bernhardt 2015 Sci Rep | 2015 | Bernhardt D, Müller M, Reichert AS, Osiewacz HD (2015) Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan. Sci Rep 5:7885. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Hecker 2015 Methods Mol Biol | 2015 | Hecker M, Sommer N, Mayer K (2015) Assessment of short- and medium-chain fatty acids on mitochondrial function in severe Inflammation. Methods Mol Biol 1265:389-96. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Kuznetsov 2015 Biochim Biophys Acta | 2015 | Kuznetsov AV, Javadov S, Sickinger S, Frotschnig S, Grimm M (2014) H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation. Biochim Biophys Acta 1853:276-84. | ROUTINE ET | Intact cells | Rat | Heart Other cell lines | |
Jeger 2015 BioMed Res Internat | 2015 | Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle Liver Other cell lines |
Negmadjanov 2015 PLOS ONE | 2015 | Negmadjanov U, Godic Z, Rizvi F, Emelyanova L, Ross G, Richards J, Holmuhamedov EL, Jahangir A (2015) TGF-β1-mediated differentiation of fibroblasts is associated with increased mitochondrial content and cellular respiration. PLOS ONE 10:e0123046. doi: 10.1371/journal.pone.0123046. | LEAK ROUTINE ET | ROX | Mouse | Fibroblast | |
Luevano-Martinez 2015 Biochim Biophys Acta | 2015 | Luévano-Martínez LA, Forni MF, Dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2015) Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress. Biochim Biophys Acta 1847:587-98. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae Fungi | |
Aroor 2015 Diabetes | 2015 | Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001. | LEAK ROUTINE OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Liver |
Rodrigues 2015 J Cell Biochem | 2015 | Rodrigues MF, Carvalho É, Pezzuto P, Rumjanek FD, Amoêdo ND (2015) Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin a on the energy metabolism of breast cancer cells. Int J Biochem Cell Biol 116:797-808. | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Hendricks 2015 Thesis | 2015 | Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse | Nervous system |
Keane 2015 Clin Sci (Lond) | 2015 | Keane KN, Calton EK, Cruzat VF, Soares MJ, Newsholme P (2015) The impact of cryopreservation on human peripheral blood leukocyte bioenergetics. Clin Sci (Lond) 128:723–33. | ROUTINE ET | Intact cells | Human | Blood cells | |
Venter 2015 J Clin Cell Immunol | 2015 | Venter G, Wijers M, Oerlemans FTJJ, Manjeri G, Fransen JAM, Wieringa B (2015) Glycolytic metabolism is differentially coupled to proliferative potential and morphodynamic capacity in RAW 264.7 and Mafb/C-Maf deficient macrophage lineages. J Clin Cell Immunol 6:1-11. | LEAK ROUTINE ET | ROX | Mouse | Blood cells Macrophage-derived | |
Adlimoghaddam 2015 J Exp Biol | 2015 | Adlimoghaddam A, Boeckstaens M, Marini AM, Treberg JR, Brassinga AK, Weihrauch D (2015) Ammonia excretion in Caenorhabditis elegans: mechanism and evidence of ammonia transport of the Rhesus protein CeRhr-1. J Exp Biol 218:675-83. | ROUTINE | Intact organism | Caenorhabditis elegans | ||
Van Rahden 2015 Am J Hum Genet | 2015 | van Rahden VA, Fernandez-Vizarra E, Alawi M, Brand K, Fellmann F, Horn D, Zeviani M, Kutsche K (2015) Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome. Am J Hum Genet 96:640-50. | LEAK ROUTINE ET | Intact cells | Human | HeLa | |
Lim 2015 Am J Cancer Res | 2015 | Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701. | LEAK ROUTINE OXPHOS | N S | Permeabilized cells Isolated mitochondria Intact cells | Human | Kidney Other cell lines HEK HeLa Fibroblast |
Seillier 2015 EMBO Mol Med | 2015 | Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18. | LEAK ROUTINE OXPHOS ET | F CIV NS ROX | Permeabilized cells Intact cells | Human Mouse | Fibroblast |
Grefte 2015 Biochim Biophys Acta | 2015 | Grefte S, Wagenaars JA, Jansen R, Willems PH, Koopman WJ (2015) Rotenone inhibits primary murine myotube formation via Raf-1 and ROCK2. Biochim Biophys Acta 1853:1606-14. | ROUTINE | Intact cells | Mouse | Skeletal muscle Other cell lines | |
Makrecka-Kuka 2015 Biomolecules | 2015 | Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system HEK |
Lages 2015 PeerJ | 2015 | Lages YM, Nascimento JM, Lemos GA, Galina A, Castilho LR, Rehen SK (2015) Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. PeerJ 3:e1486. | LEAK ROUTINE ET | ROX | Intact cells | Human | Stem cells |
Plecita-Hlavata 2015 J Bioenerg Biomembr | 2015 | Plecitá-Hlavatá L, Ježek J, Ježek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76. | LEAK ROUTINE ET | Intact cells | Human | Liver | |
Schirris 2015 Cell Metab | 2015 | Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407. | ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Lisak 2015 Cell Death Differ | 2015 | Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A (2015) BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival. Cell Death Differ 23:358-68. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells Lymphocyte |
Schoeckel 2015 Cancer Metab | 2015 | Schöckel L, Glasauer A, Basit F, Bitschar K, Truong H, Erdmann G, Algire C, Hägebarth A, Willems PH, Kopitz C, Koopman WJ, Héroult M (2015) Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth. Cancer Metab 3:11. | ROUTINE | ROX | Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Falabella 2015 Oxid Med Cell Longev | 2015 | Falabella M, Forte E, Magnifico MC, Santini P, Arese M, Giuffrè A, Radić K, Chessa L, Coarelli G, Buscarinu MC, Mechelli R, Salvetti M, Sarti P (2015) Evidence for detrimental cross interactions between reactive oxygen and nitrogen species in Leber’s hereditary optic neuropathy cells. Oxid Med Cell Longev 3187560. | ROUTINE | ROX | Intact cells | Human | Blood cells Lymphocyte |
Martos 2015 Plant Physiol Biochem | 2015 | Martos GG, Terán Mdel M, Díaz Ricci JC (2015) The defence elicitor AsES causes a rapid and transient membrane depolarization, a triphasic oxidative burst and the accumulation of nitric oxide. Plant Physiol Biochem 97:443-50. | ROUTINE | Intact cells | Plants | ||
Victorino 2015 Tumour Biol | 2015 | Victorino VJ, Barroso WA, Assunção AK, Cury V, Jeremias IC, Petroni R, Chausse B, Ariga SK, Herrera AC, Panis C, Lima TM, Souza HP (2015) PGC-1β regulates HER2-overexpressing breast cancer cells proliferation by metabolic and redox pathways. Tumour Biol 37:6035-44. | LEAK ROUTINE ET | ROX | Intact cells | Human | Genital Other cell lines |
Lee 2015 Methods Mol Biol | 2015 | Lee W, Kelly RD, Yeung KY, Cagnone G, McKenzie M, John JC (2015) Analysis of mitochondrial DNA in induced pluripotent and embryonic stem cells. Methods Mol Biol 1330:219-52. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Stem cells |
Rodrigues 2016 Biochem J | 2015 | Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645 | LEAK ROUTINE OXPHOS ET | F N S ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
Kawalec 2015 PLoS One | 2015 | Kawalec M, Boratyńska-Jasińska A, Beręsewicz M, Dymkowska D, Zabłocki K, Zabłocka B (2015) Mitofusin 2 deficiency affects energy metabolism and mitochondrial biogenesis in MEF cells. PLoS One 10:e0134162. | LEAK ROUTINE ET | Permeabilized cells | Mouse | Fibroblast | |
Sundaram 2015 Mol Microbiol | 2015 | Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Kasvandik 2015 J Proteome Res | 2015 | Kasvandik S, Samuel K, Peters M, Eimre M, Peet N, Roost AM, Padrik L, Paju K, Peil L, Salumets A (2015) Deep quantitative proteomics reveals extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells. J Proteome Res 15:572-84. | LEAK ROUTINE ET | ROX | Human | Genital Other cell lines | |
Du 2015 J Biol Chem | 2015 | Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Nervous system Islet cell;pancreas;thymus |
Tesori 2015 Sci Rep | 2015 | Tesori V, Piscaglia AC, Samengo D, Barba M, Bernardini C, Scatena R, Pontoglio A, Castellini L, Spelbrink JN, Maulucci G, Puglisi MA, Pani G, Gasbarrini A (2015) The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing. Sci Rep 5:9149. | LEAK ROUTINE ET | Intact cells | Rat | Liver Other cell lines Stem cells | |
Bock 2015 Thesis | 2015 | Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Lung;gill Macrophage-derived |
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol | 2015 | Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57. | LEAK ROUTINE OXPHOS ET | N CIV Other combinations | Isolated mitochondria Intact cells | Human Bovines | Endothelial;epithelial;mesothelial cell Fibroblast |
Khiati 2015 Proc Natl Acad Sci U S A | 2015 | Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y (2015) Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration. Proc Natl Acad Sci U S A 112:11282-7. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
Schoettl 2015 Mol Metab | 2015 | Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42. | LEAK ROUTINE OXPHOS ET | F N S ROX | Isolated mitochondria Intact cells | Mouse | Fat Other cell lines |
Hals 2015 PLoS One | 2015 | Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Six 2015 Cell Death Dis | 2015 | Six E, Lagresle-Peyrou C, Susini S, De Chappedelaine C, Sigrist N, Sadek H, Chouteau M, Cagnard N, Fontenay M, Hermine O, Chomienne C, Reynier P, Fischer A, André-Schmutz I, Gueguen N, Cavazzana M (2015) AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages. Cell Death Dis 6:e1856. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Other cell lines |
Hagl 2015 Molecules | 2015 | Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Nervous system Other cell lines |
Cassina 2015 Biol Reprod | 2015 | Cassina AM, Silveira P, Cantu L, Montes JM, Radi R, Sapiro R (2015) Defective human sperm cells are associated with mitochondrial dysfunction and oxidant production. Biol Reprod 93:119. | LEAK ROUTINE ET | ROX | Human | Genital | |
Lehtola 2015 Master's Thesis | 2015 | Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Blood cells Other cell lines Lymphocyte |
Taferner 2015 PLoS One | 2015 | Taferner A, Pircher H, Koziel R, von Grafenstein S, Baraldo G, Palikaras K, Liedl KR, Tavernarakis N, Jansen-Dürr P (2015) FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans. PLoS One 10(8):e0134161. | ROUTINE | Intact organism | Caenorhabditis elegans Nematodes | ||
Garama 2015 Mol Cell Biol | 2015 | Garama DJ, Harris TJ, White CL, Rossello FJ, Abdul-Hay M, Gough DJ, Levy DE (2015) A synthetic lethal interaction between glutathione synthesis and mitochondrial reactive oxygen species provides a tumor-specific vulnerability dependent on STAT3. Mol Cell Biol 35:3646-56. | LEAK ROUTINE ET | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Fibroblast | |
Ikaga 2015 Biochem Biophys Rep | 2015 | Ikaga R, Namekatac I, Kotiadisd VN, Ogawab H, Duchend MR, Tanakac H, Iida-Tanakab N (2015) Knockdown of aquaporin-8 induces mitochondrial dysfunction in 3T3-L1 cells. Biochem Biophys Rep 4:187–95. | LEAK ROUTINE ET | CIV ROX | Intact cells | Mouse | Fat Other cell lines |
Martinez 2015 Thesis | 2015 | Martínez Gasca B (2015) Generacion de modelos celulares para el estudio del efecto fenotipico de la variacion genetica en el mtDNA. Thesis 1-35. | ROUTINE | Intact cells | Human | Liver Other cell lines | |
Renner 2015 Eur J Immunol | 2015 | Renner K, Geiselhöringer AL, Fante M, Bruss C, Färber S, Schönhammer G, Peter K, Singer K, Andreesen R, Hoffmann P, Oefner P, Herr W, Kreutz M (2015) Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions. Eur J Immunol 45:2504-16. | LEAK ROUTINE ET | Intact cells | Human | Blood cells Lymphocyte | |
Assmann 2014 PhD Thesis | 2015 | Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Pig | Kidney Other cell lines |
Llobet 2015 Dis Model Mech | 2015 | Llobet L, Toivonen JM, Montoya J, Ruiz-Pesini E, López-Gallardo E (2015) OXPHOS xenobiotics alter adipogenic differentiation at concentrations found in human blood. Dis Model Mech 8:1441-55. | LEAK ROUTINE ET | Intact cells | Human | Fat Stem cells | |
Banerjee 2015 Placenta | 2015 | Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32. | ROUTINE OXPHOS ET | N | Intact cells Permeabilized tissue | Human | Genital |
Ofer 2015 Mol Endocrinol | 2015 | Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707. | ROUTINE OXPHOS ET | F N NS | Permeabilized cells Intact cells | Human | Genital Other cell lines |
Peyta 2015 Biochim Biophys Acta | 2015 | Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2015) Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia. Biochim Biophys Acta 1851:1490-500. | LEAK ROUTINE OXPHOS ET | NS | Permeabilized cells Intact cells | Rat | Liver Other cell lines |
Boss 2015 US Patent | 2015 | Boss OD, Crisan M, Giacobino JP, (2015) Brown adipocyte progenitors in human sceletal muscle. US Patent US 2015/0240206 A1. | LEAK ROUTINE ET | ROX | Permeabilized cells | Human Mouse | Skeletal muscle Endothelial;epithelial;mesothelial cell Fat |
Farrar 2015 US Patent | 2015 | Farrar GJ, Millington-Ward S, Chadderton N (2015) Variants of yeast ndi1 gene, and uses thereof in the treatment of disease associated with mitochondrial dysfunction. US Patent WO 2013093029 A3. | ROUTINE | ROX | Human | HeLa | |
Matallo 2014 Nitric Oxide | 2014 | Matallo J, Vogt J, McCook O, Wachter U, Tillmans F, Groeger M, Szabo C, Georgieff M, Radermacher P, Calzia E (2014) Sulfide-inhibition of mitochondrial respiration at very low oxygen concentrations. Nitric Oxide 15:79-84. | ROUTINE ET | Intact cells | Mouse | Lung;gill Macrophage-derived | |
Ren 2014 Sci Rep | 2014 | Ren JG, Seth P, Clish CB, Lorkiewicz PK, Higashi RM, Lane AN, Fan TW, Sukhatme VP (2014) Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling. Sci Rep 4:5414. | ROUTINE | Intact cells | Human | Lung;gill Other cell lines | |
Larsen 2014 Am J Clin Nutr | 2014 | Larsen FJ, Schiffer TA, Ekblom B, Mattsson MP, Checa A, Wheelock CE, Nyström T, Lundberg JO, Weitzberg E (2014) Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans. Am J Clin Nutr 99:843-50. | LEAK ROUTINE OXPHOS | Intact cells Permeabilized cells | Human | Skeletal muscle Stem cells | |
Hort 2014 Biochimie | 2014 | Hort MA, Straliotto MR, de Oliveira J, Amoêdo ND, da Rocha JB, Galina A, Ribeiro-do-Valle RM, de Bem AF (2014) Diphenyl diselenide protects endothelial cells against oxidized low density lipoprotein-induced injury: Involvement of mitochondrial function. Biochimie 105:172-81. | LEAK ROUTINE ET | Intact cells | Bovines | Other cell lines | |
Cheng 2014 Science | 2014 | Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR6, Li Y, Ifrim DC, Arts RJ, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG (2014) mTOR- and HIF-1 α–mediated aerobic glycolysis as metabolic basis for trained immunity. Science 345:1250684. | LEAK ROUTINE ET | Human | Blood cells Other cell lines | ||
Breton-Romero 2014 Biochim Biophys Acta | 2014 | Bretón-Romero R, Acín-Perez R, Rodríguez-Pascual F, Martínez-Molledo M, Brandes RP, Rial E, Enríquez JA, Lamas S (2014) Laminar shear stress regulates mitochondrial dynamics, bioenergetics responses and PRX3 activation in endothelial cells. Biochim Biophys Acta 1843:2403-13. | ROUTINE | Intact cells | Endothelial;epithelial;mesothelial cell HUVEC | ||
Di Noia 2014 J Biol Chem | 2014 | Di Noia MA, Todisco S, Cirigliano A, Rinaldi T, Agrimi G, Iacobazzi V, Palmieri F (2014) The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem 289:33137-48. | ROUTINE ET | Intact cells | Saccharomyces cerevisiae | ||
Brahma 2014 J Lipid Res | 2014 | Brahma MK, Adam RC, Pollak NM, Jaeger D, Zierler KA, Poecher N, Schreiber R, Romauch M, Moustafa T, Eder S, Ruelicke T, Preiss-Landl K, Lass A, Zechner R, Haemmerle G (2014) Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis. J Lipid Res 55:2229-41. | LEAK ROUTINE ET | Intact cells | Mouse Rat | Heart | |
Logan 2014 Nat Genet | 2014 | Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R. UK10K Consortium, Duchen MR, Muntoni F, Sheridan E (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
Mishra 2014 Invest Ophthalmol Vis Sci | 2014 | Mishra M, Kowluru RA (2014) Retinal mitochondrial DNA mismatch repair in the development of diabetic retinopathy, and its continued progression after termination of hyperglycemia. Invest Ophthalmol Vis Sci. 55:6960-7. | ROUTINE | Intact cells | Bovines | Endothelial;epithelial;mesothelial cell | |
Schoerner 2014 Thesis University Giessen | 2014 | Schörner S (2014) Changes in function of mitochondrial respiratory chain in pulmonary artery smooth muscle cells under conditions of chronic hypoxia : measurements by respirometry and remission-spectrophotometry. Thesis University Giessen 130 pp. | LEAK ROUTINE ET | ROX | Rabbit | Endothelial;epithelial;mesothelial cell | |
Karabatsiakis 2014 Transl Psychiatry | 2014 | Karabatsiakis A, Boeck C, Salinas-Manrique J, Kolassa S, Calzia E, Dietrich DE, Kolassa IT (2014) Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Transl Psychiatry 4:e397. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Konickova 2014 Annals Hepatol | 2014 | Konickova R, Vankova K, Vanikova J, Vanova K, Muchova L, Subhanova I, Zadoinova M, Zelenka J, Dvorak A, Kolar M,Strnad H, Rimpelova S, Ruml T, Wong RJ, Vitek L (2014) Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds. Annals Hepatol 13:273-83. | ROUTINE ET | Human | Other cell lines | ||
Widmann 2014 Thesis | 2014 | Widmann M (2014) Effekte von Noradrenalin und LPS auf die mitochondriale Atmung von Alveolarmakrophagen. Thesis Universität Ulm, Medizinische Fakultät. 63 pp. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Lung;gill Other cell lines |
Brandt 2014 Chem Biol Interact | 2014 | Brandt AP, do Rocio Andrade Pires A, Rocha ME, Noleto GR, Acco A, de Souza CE, Echevarria A, Dos Santos Canuto AV, Cadena SM (2014) Sydnone SYD-1 affects the metabolic functions of isolated rat hepatocytes. Chem Biol Interact 218C:107-14. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Liver |
Hereng 2014 Human Reprod | 2014 | Hereng TH, Elgstoen KBP, Eide L, Rosendal KR, Skalhegg BS (2014) Serum albumin and HCO3 2 regulate separate pools of ATP in human spermatozoa. Human Reprod 29:918-30. | LEAK ROUTINE ET | Intact cells | Human | Genital | |
Piel 2014 Acta Physiol (Oxf) | 2014 | Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Other cell lines Platelet |
Doridot 2014 Antioxid Redox Signal | 2014 | Doridot LD Chatre LD, Ducat A, Vilotte JL, Lombes A, Méhats C, Barbaux S, Calicchio R, Ricchetti M, Vaiman D (2014) Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia associated gene. Antioxid Redox Signal 21:819-34. | LEAK ROUTINE ET | ROX | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
De Oliveira 2014 Cell Tiss Res | 2014 | De Oliveira GP, Cortez E, Araujo GJ, de Carvalho Sabino KC, Neves FA, Bernardo AF, de Carvalho SN, Moura AS, Carvalho L, Thole AA (2014) Impaired mitochondrial function and reduced viability in bone marrow cells of obese mice. Cell Tiss Res 357:185-94. | LEAK ROUTINE OXPHOS | NS | Permeabilized cells | Mouse | Stem cells |
Chini 2014 Clin Cancer Res | 2014 | Chini CC, Gonzalez Guerrico A, Nin V, Camacho-Pereira J, Escande C, Barbosa M, Chini EN (2014) Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors. Clin Cancer Res 20:120-30. | ROUTINE ET | Intact cells | Human | Islet cell;pancreas;thymus Other cell lines | |
Chakraborty 2014 J Cardiovasc Dis | 2014 | Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue | Rat | Heart Blood cells |
Van Bergen 2014 Mitochondrion | 2014 | Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Nervous system Blood cells |
Cotoia 2014 PLoS One | 2014 | Cotoia A, Scrima R, Gefter JV, Piccoli C, Cinnella G, Dambrosio M, Fink MP, Capitanio N (2014) p-Hydroxyphenylpyruvate, an intermediate of the Phe/ Tyr catabolism, improves mitochondrial oxidative metabolism under stressing conditions and prolongs survival in rats subjected to profound hemorrhagic shock. PLoS One 9:e90917. | LEAK ROUTINE ET | Intact cells | Rat | ||
Schmidl 2014 Blood | 2014 | Schmidl C, Renner K, Peter K, Eder R, Lassmann T, Balwierz PJ, Itoh M, Nagao-Sato S, Kawaji H, Carninci P, Suzuki H, Hayashizaki Y, Andreesen R, Hume DA, Hoffmann P, Forrest AR, Kreutz MP, Edinger M, Rehli M (2014) Transcription and enhancer profiling in human monocyte subsets. Blood 123:e90-9. | ROUTINE | CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
Rudnicki 2014 United States Patent Application Publication | 2014 | Rudnicki MA, Yin Hang (2014) MICRORNA INHIBITORS. United States Patent Application Publication 1-49. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle Fat |
Felser 2014 Toxicology II | 2014 | Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, Krähenbühl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46. | LEAK ROUTINE OXPHOS ET | N S ROX | Intact cells | Human | Liver Other cell lines |
Kramer 2014 J Vis Exp | 2014 | Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM (2014) Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets. J Vis Exp 2014 Mar 27(85). doi: 10.3791/51301. | LEAK ROUTINE ET | Intact cells | Human | Blood cells Platelet | |
Boczek 2014 Biomed Res Int | 2014 | Boczek T, Lisek M, Ferenc B, Kowalski A, Wiktorska M, Zylinska L (2014) Silencing of plasma membrane Ca2+-ATPase isoforms 2 and 3 impairs energy metabolism in differentiating PC12 cells. Biomed Res Int 2014:735106. | LEAK ROUTINE ET | Rat | Nervous system Other cell lines | ||
Glaser 2014 Thesis | 2014 | Glaser V (2014) Efeitos da hiperglicemia cronica e seus metabolitos, metilglioxal e produtos terminais de glicacao, na fisiologia e dinamica mitochondrial no sistema nervoso central. PhD Thesis 1-117. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Nervous system Other cell lines |
Hecker 2014 JPEN | 2014 | Hecker M, Sommer N, Voigtmann H, Pak O, Mohr A, Wolf M, Vadász I, Herold S, Weissmann N, Morty R, Seeger W, Mayer K (2014) Impact of short- and medium-chain fatty acids on mitochondrial function in severe inflammation. J Parenter Enteral Nutr 38:587-94. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Blood cells HUVEC | |
Carriere 2014 Diabetes | 2014 | Carrière A, Jeanson Y, Berger-Müller S, André M, Chenouard V, Arnaud E, Barreau C, Walther R, Galinier A, Wdziekonski B, Villageois P, Louche K, Collas P, Moro C, Dani C, Villarroya F, Casteilla L (2014) Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure. Diabetes 63:3253-65. | LEAK ROUTINE ET | Intact cells | Mouse | Fat | |
Bayot 2014 Biochimie | 2014 | Bayot A, Gareil M, Chavatte L, Hamon MP, L'hermitte-Stead C, Beaumatin F, Priault M, Rustin P, Lombès A, Friguet B, Bulteau AL (2014) Effect of Lon protease knockdown on mitochondrial function in HeLa cells. Biochimie 100:38-47. | LEAK ROUTINE ET | Human | Endothelial;epithelial;mesothelial cell HeLa | ||
Corona 2014 Exp Neurol | 2014 | Corona JC, de Souza SC, Duchen MR (2014) PPARγ activation rescues mitochondrial function from inhibition of 2 complex I and loss of PINK1. Exp Neurol 253:16-27. | LEAK ROUTINE ET | Intact cells | Human | Neuroblastoma | |
Gnaiger 2014 MitoPathways | 2014 |
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. — see 5th edition: Gnaiger 2020 BEC MitoPathways. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Skeletal muscle Fibroblast |
Mandò 2014 Am J Physiol Endocrinol Metab | 2014 | Mandò C, De Palma C, Stampalija T, Anelli GM, Figus M, Novielli C, Parisi F, Clementi E, Ferrazzi E, Cetin I (2014) Placental mitochondrial content and function in intrauterine growth restriction and preeclampsia. Am J Physiol Endocrinol Metab 306:E404-13. | ROUTINE OXPHOS | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Genital |
Sonkar 2014 FASEB J | 2014 | Sonkar VK, Kulkarni PP, Dash D (2014) Amyloid beta peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization. FASEB J 28:1819-29. | LEAK ROUTINE | ROX | Intact cells | Human Mouse | Blood cells Platelet |
Fiuza 2014 Free Radic Res | 2014 | Fiuza B, Subelzú N, Calcerrada P, Straliotto MR, Piacenza L, Cassina A, Rocha JB, Radi R, de Bem AF, Peluffo G (2014) Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of peroxiredoxins. Free Radic Res 49:122-32. | LEAK ROUTINE ET | Intact cells | Bovines | Endothelial;epithelial;mesothelial cell | |
D'Aprile 2014 Stem Cells | 2014 | D'Aprile A, Scrima R, Quarato G, Tataranni T, Falzetti F, Di Ianni M, Gemei M, Del Vecchio L, Piccoli C, Capitanio N (2014) Hematopoietic stem/progenitor cells express myoglobin and neuroglobin: adaptation to hypoxia or prevention from oxidative stress? Stem Cells 32:1267-77. | ROUTINE | Intact cells | Human | Stem cells | |
Hirzel 2014 PhD Thesis | 2014 | Hirzel E (2014) Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies. PhD Thesis 1-106. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Fat Other cell lines |
Casanova 2014 Biochim Biophys Acta | 2014 | Casanova E, Baselga-Escudero L, Ribas-Latre A, Arola-Arnal A, Bladé C, Arola L, Salvadó MJ (2014) Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes. Biochim Biophys Acta 1837:783-91. | LEAK ROUTINE ET | N | Intact cells | Rat | Skeletal muscle Other cell lines |
Zhang 2013 PLoS One | 2013 | Zhang Z, Tsukikawa M, Peng M, Polyak E, Nakamaru-Ogiso E, Ostrovsky J, McCormack S, Place E, Clarke C, Reiner G, McCormick E, Rappaport E, Haas R, Baur JA, Falk MJ (2013) Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. PLoS One 8:e69282. | LEAK ROUTINE OXPHOS ET | N | Permeabilized cells Intact cells | Human | Fibroblast |
Ceusters 2013 Mitochondrion | 2013 | Ceusters Justine D, Mouithys-Mickalad AA, Franck TJ, Derochette S, Vanderplasschen A, Deby-Dupont GP, Serteyn DA (2013) Effect of myeloperoxidase and anoxia/reoxygenation on mitochondrial respiratory function of cultured primary equine skeletal myoblasts. Mitochondrion 13:410-16. | LEAK ROUTINE OXPHOS ET | Permeabilized cells | Horse | Skeletal muscle |