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From Bioblast
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Friederich 2017 Hum Mol Genet2017Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16.ROUTINE
OXPHOS
ET
LEAK
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
HumanFibroblast
Kang 2017 Mol Cell2017Kang Y, Stroud DA, Baker MJ, De Souza DP, Frazier AE, Liem M, Tull D, Mathivanan S, McConville MJ, Thorburn DR, Ryan MT, Stojanovski D (2017) Sengers Syndrome-associated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex. Mol Cell 67:457-70.ROUTINE
ET
Intact cellsHuman
Boutant 2017 EMBO J2017Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58.ROUTINE
LEAK
OXPHOS
ET
ROX
N
S
NS
Intact cells
Homogenate
Isolated mitochondria
MouseFat
Fibroblast
Westerlund 2017 Pediatr Res2017Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65.LEAK
ROUTINE
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
HumanPlatelet
Blood cells
Favero 2017 Thesis2017Favero BC (2017) Efeitos da leucina sobre a via da mTOR e da miostatina em cultura celular de miotúbulos. Dissertation p55.LEAK
ROUTINE
ET
MouseSkeletal muscle
Michalak 2017 Oxid Med Cell Longev2017Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574.LEAK
ROUTINE
ET
ROXIntact cellsBlood cells
Permer 2017 Bachelor Thesis2017Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56.LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
ROX
Permeabilized cells
Intact cells
HumanOther cell lines
HEK
Xu 2017 J Hum Genet2017Xu B, Li X, Du M, Zhou C, Fang H, Lyu J, Yang Y (2017) Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. J Hum Genet 62:291-7.LEAK
ROUTINE
Intact cellsHumanBlood cells
Platelet
JanssenDuijghuijsen 2017 Front Physiol2017JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794.LEAK
ROUTINE
ET
ROXIntact cellsHumanEndothelial;epithelial;mesothelial cell
Other cell lines
Cunha-de 2017 Thesis2017Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160.LEAK
ROUTINE
OXPHOS
ET
N
NS
ROX
Intact cells
Permeabilized cells
HumanLiver
Other cell lines
Mantilla 2017 PLOS Pathog2017Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158.LEAK
OXPHOS
ET
ROUTINE
S
ROX
N
Permeabilized cells
Intact cells
Protists
Bombaca 2017 Free Radic Biol Med2017Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66.ROUTINECIV
ROX
Intact cellsProtists
Pfeiffer 2017 Free Radic Biol Med2017Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9.LEAK
ROUTINE
OXPHOS
ET
N
NS
ROX
Permeabilized cellsMouseFibroblast
Cervoni 2017 J Exp Biol2017Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46.LEAK
ROUTINE
OXPHOS
ET
N
ROX
Intact cells
Xiong 2017 J Am Heart Assoc2017Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495.LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Intact cells
MouseEndothelial;epithelial;mesothelial cell
Ruiz 2017 Brain Pathol2017Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30.LEAK
ROUTINE
ET
ROXIntact cellsHuman
Mouse
Nervous system
Fibroblast
De Souza 2017 Thesis2017de Souza LF (2017) Modulação redox de peroxirredoxinas e a participação dos sistemas da GSH e da Trx na proteção/função celular. Tese (doutorado) p103.LEAK
ROUTINE
ET
Intact cellsHumanOther cell lines
Djordjevic 2017 Neuroscience2017Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92.ROUTINE
OXPHOS
ET
N
S
ROX
Isolated mitochondriaMouseNervous system
Welker 2017 Thesis2017Welker L (2017) Metabolic and morphologic shifts in Neuro2a cells cultured in galactose medium. Master's Thesis p26.LEAK
ROUTINE
ET
Intact cellsMouse
Dechandt 2017 J Bioenerg Biomembr2017Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411.LEAK
ROUTINE
ET
F
N
ROX
Permeabilized cells
Intact cells
RatLiver
Singhal 2017 Mol Biol Cell2017Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D (2017) Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Mol Biol Cell 28:2609-22.ROUTINE
ET
Isolated mitochondriaSaccharomyces cerevisiae
Jang 2017 Clin Toxicol (Phila)2017Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84.LEAK
ROUTINE
OXPHOS
ET
F
S
CIV
NS
ROX
Intact cellsBlood cells
Tueller 2017 Biochem Biophys Res Commun2017Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72.LEAK
ROUTINE
OXPHOS
F
N
NS
ROX
Permeabilized cells
Intact cells
Skeletal muscle
Zhou 2017 Oxid Med Cell Longev2017Zhou H, Nie K, Qiu R, Xiong J, Shao X, Wang B, Shen L, Lyu J, Fang H (2017) Generation and bioenergetic profiles of cybrids with east Asian mtDNA haplogroups. Oxid Med Cell Longev 2017:1062314.LEAK
ROUTINE
Intact cellsHuman
Frawley 2017 Chem Res Toxicol2017Frawley KL, Cronican AA, Pearce LL, Peterson J (2017) Sulfide toxicity and its modulation by nitric oxide in bovine pulmonary artery endothelial cells. Chem Res Toxicol 30:2100-9.ROUTINEIntact cellsBovinesEndothelial;epithelial;mesothelial cell
Profilo 2017 Biochim Biophys Acta2017Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35.LEAK
ET
ROUTINE
ROXIntact cellsMouseNervous system
Other cell lines
Neuroblastoma
De Carvalho 2017 Sci Rep2017de Carvalho AETS, Bassaneze V, Forni MF, Keusseyan AA, Kowaltowski AJ, Krieger JE (2017) Early postnatal cardiomyocyte proliferation requires high oxidative energy metabolism. Sci Rep 7:15434.ROUTINEIntact cellsRatHeart
Wu 2017 Sci Rep2017Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191.LEAK
OXPHOS
ET
ROUTINE
N
NS
ROX
CIV
Permeabilized cells
Intact cells
HumanBlood cells
Platelet
Lang 2017 Aging (Albany NY)2017Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP (2017) SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. Aging (Albany NY) 9:2163-89.LEAK
ET
ROUTINE
ROXIntact cellsHumanKidney
HEK
Scrima 2017 PLOS ONE2017Scrima R, Menga M, Pacelli C, Agriesti F, Cela O, Piccoli C, Cotoia A, De Gregorio A, Gefter JV, Cinnella G, Capitanio N (2017) Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift. PLOS ONE 12:e0188683.LEAK
ROUTINE
ET
ROXIntact cellsHuman
Mouse
Endothelial;epithelial;mesothelial cell
Blood cells
Fibroblast
Macrophage-derived
Zholobenko 2017 PLOS ONE2017Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691.LEAK
OXPHOS
ET
ROUTINE
F
N
S
NS
ROX
Permeabilized cells
Intact cells
RatHeart
Schaefer 2017 Neurophotonics2017Schaefer PM, Hilpert D, Niederschweiberer M, Neuhauser L, Kalinina S, Calzia E, Rueck A, von Einem B, von Arnim CAF (2017) Mitochondrial matrix pH as a decisive factor in neurometabolic imaging. Neurophotonics 4:045004.ROUTINE
ET
CIV
ROX
Kidney
HEK
Comelli 2017 J Bioenerg Biomembr2017Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52.LEAK
ROUTINE
OXPHOS
ET
N
Gp
CIV
NS
ROX
Intact cells
Permeabilized cells
HumanNervous system
Jang 2017 Biol Open2017Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9.LEAK
ROUTINE
ET
N
S
CIV
NS
ROX
Permeabilized cells
Intact cells
HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Ma 2017 Int J Cancer2017Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. Int J Cancer 142:1786-96.LEAK
ROUTINE
ET
Intact cellsHuman
Ortega-Dominguez 2017 Food Chem Toxicol2017Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85.LEAK
ROUTINE
OXPHOS
N
NS
Isolated mitochondria
Wang 2017 J Am Heart Assoc2017Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812.ROUTINE
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized cellsRatEndothelial;epithelial;mesothelial cell
Garcia-Neto 2017 PLOS ONE2017Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Luévano-Martínez LA (2017) High osmolarity environments activate the mitochondrial alternative oxidase in Debaryomyces Hansenii. PLOS ONE 12:e0169621. https://doi.org/10.1371/journal.pone.0169621ROUTINECIV
ROX
Isolated mitochondria
Intact cells
Fungi
Blecha 2017 Free Radic Biol Med2017Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J (2017) Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death. Free Radic Biol Med 112:253-66.ROUTINE
OXPHOS
SIntact cellsEndothelial;epithelial;mesothelial cell
Beresewicz 2017 PLOS ONE2017Beręsewicz M, Boratyńska-Jasińska A, Charzewski Ł, Kawalec M, Kabzińska D, Kochański A, Krzyśko KA, Zabłocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLOS ONE 12:e0169999.LEAK
ET
ROUTINE
Intact cellsHumanEndothelial;epithelial;mesothelial cell
Fibroblast
Radenkovic 2017 Biochem Pharmacol2017Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52.ROUTINE
OXPHOS
ET
N
S
CIV
NS
ROX
Permeabilized cellsHumanOther cell lines
Bansal 2017 Environ Health Perspect2017Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA (2017) Sex- and dose-specific effects of maternal bisphenol A exposure on pancreatic islets of first- and second-generation adult mice offspring. Environ Health Perspect 125:097022.LEAK
ROUTINE
ET
ROXIntact cellsMouseIslet cell;pancreas;thymus
MiPNet21.14 Reference sample HRR2016-10-19
O2k-Protocols

Development of a reference sample for HRR.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
Other combinations
ROX
Intact cells
Permeabilized cells
HumanHEK
MiPNet21.12 Comparison mt respiration media2016-10-18
O2k-Protocols

O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.

LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Intact cells
Permeabilized cells
HumanHEK
MiPNet08.09 CellRespiration2016-08-11
O2k-Procedures contents

High-resolution respirometry and coupling-control protocol with living cells: ROUTINE, LEAK, ET-pathway, ROX.

LEAK
ROUTINE
ET
Intact cellsHumanBlood cells
Lymphocyte
MiPNet10.04 CellRespiration2016-08-08
O2k-Protocols

An experiment with high-resolution respirometry: coupling control in cell respiration.

LEAK
ROUTINE
ET
ROXIntact cellsMouseBlood cells
Jang 2016 J Intensive Care Med2016Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94.LEAK
ROUTINE
ET
ROXIntact cellsHumanBlood cells
Lymphocyte
Zhunussova 2016 PLOS ONE2016Zhunussova A, Vitol EA, Polyak B, Tuleukhanov S, Brooks AD, Sensenig R, Friedman G, Orynbayeva Z (2016) Mitochondria-mediated anticancer effects of non-thermal atmospheric plasma. PLOS ONE 11:e0156818.LEAK
ROUTINE
ET
Intact cellsHumanGenital
Other cell lines
Zelenka 2016 Oxid Med Cell Longev2016Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.ROUTINEIntact cells
Isolated mitochondria
RatLiver
Kidney
Fibroblast
Camacho-Pereira 2016 Cell Metab2016Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39.LEAK
ROUTINE
OXPHOS
ET
S
ROX
Isolated mitochondria
Intact cells
Human
Mouse
Liver
Lung;gill
Other cell lines
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