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From Bioblast
| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Rosca 2012 Diabetes | 2012 | Rosca MG, Vazquez EJ, Chen Q, Kerner J, Kern TS, Hoppel CL (2012) Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes. Diabetes 61:2074-83. https://doi.org/10.2337/db11-1437 | F | ||||
| Witkowski 2011 J Biol Chem | 2011 | Witkowski A, Thweatt J, Smith S (2011) Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis. J Biol Chem 286:33729-36. | F | Isolated mitochondria | Human | HEK | |
| Boyle 2011 Int J Obes | 2011 | Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA (2011) Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. Int J Obes 36:1025-31. | F | Permeabilized cells | Human | Skeletal muscle | |
| Begriche 2011 J Hepatol | 2011 | Begriche K, Massart J, Robin MA, Borgne-Sanchez A, Fromenty B (2011) Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 54:773-94. https://doi.org/10.1016/j.jhep.2010.11.006 | F | ||||
| Pajuelo-Reguera 2011 Br J Nutr | 2011 | Pajuelo-Reguera D, Quesada H, Dรญaz S, Fernรกndez-Iglesias A, Arola-Arnal A, Bladรฉ C, Salvadรณ J, Arola L (2011) Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats. Br J Nutr 28:1-9. | LEAK OXPHOS ET | F N | Isolated mitochondria | Rat | Fat |
| Goetzman 2011 Prog Mol Biol Transl Sci | 2011 | Goetzman ES (2011) Modeling disorders of fatty acid metabolism in the mouse. Prog Mol Biol Transl Sci 100:389-417. https://doi.org/10.1016/B978-0-12-384878-9.00010-8 | F | Mouse | |||
| Pike 2011 Biochim Biophys Acta | 2011 | Pike LS, Smift AL, Croteau NJ, Ferrick DA, Wu M (2011) Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. https://doi.org/10.1016/j.bbabio.2010.10.022 | ROUTINE | F | Intact cells | Other cell lines | |
| Pesta 2011 Am J Physiol Regul Integr Comp Physiol | 2011 | Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078โ87. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Timmers 2011 Cell Metab | 2011 | Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
| Jacobs 2011 J Appl Physiol | 2011 | Jacobs R, Rasmussen P, Siebenmann C, Dรญaz V, Pesta D, Gnaiger E, Nordsborg NB, Robach P, Lundby C (2011) Determinants of time trial performance and maximal incremental exercise in highly trained endurance athletes. J Appl Physiol 111:1422โ30. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Lemieux 2011 Int J Biochem Cell Biol | 2011 | Lemieux H, Semsroth S, Antretter H, Hรถfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729โ38. https://doi.org/10.1016/j.biocel.2011.08.008 | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
| Henique 2010 J Biol Chem | 2010 | Henique C, Mansouri A, Fumey G, Lenoir V, Girard J, Bouillaud F, Prip-Buus C, Cohen I (2010) Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis. J Biol Chem 285:36818-27. | F | Intact cells | Mouse | Skeletal muscle Other cell lines | |
| Wang 2010 J Biol Chem | 2010 | Wang Y, Mohsen AW, Mihalik SJ, Goetzman ES, Vockley J (2010) Evidence for physical association of mitochondrial fatty acid oxidation and oxidative phosphorylation complexes. J Biol Chem 285:29834-41. https://doi.org/10.1074/jbc.M110.139493 | F | Isolated mitochondria | Rat | Liver | |
| Remels 2010 Mol Cell Endocrinol | 2010 | Remels AH, Langen RC, Schrauwen P, Schaart G, Schols AM, Gosker HR (2010) Regulation of mitochondrial biogenesis during myogenesis. Mol Cell Endocrinol 315:113-20. | ROUTINE OXPHOS ET | F | Permeabilized cells | Mouse Rat | Skeletal muscle Other cell lines |
| Watmough 2010 Biochim Biophys Acta | 2010 | Watmough NJ, Frerman FE (2010) The electron transfer flavoprotein: ubiquinone oxidoreductases. Biochim Biophys Acta 1797:1910-6. https://doi.org/10.1016/j.bbabio.2010.10.007 | F | ||||
| Houten 2010 J Inherit Metab Dis | 2010 | Houten SM, Wanders RJ (2010) A general introduction to the biochemistry of mitochondrial fatty acid ฮฒ-oxidation. J Inherit Metab Dis 33:469-77. | F | Enzyme | Human | ||
| Hoeks 2010 Diabetes | 2010 | Hoeks J, van Herpen NA, Mensink M, Moonen-Kornips E, van Beurden D, Hesselink MK, Schrauwen P (2010) Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 59:2117-25. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Flamment 2009 Am J Physiol Endocrinol Metab | 2009 | Flamment M, Gueguen N, Wetterwald C, Simard G, Malthiรจry Y, Ducluzeau PH (2009) Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 297:E1162-70. | LEAK OXPHOS ET | F N S CIV | Isolated mitochondria | Rat | Liver |
| Kwon 2009 Thesis | 2009 | Kwon OS (2009) Effect of acute exercise or fasting on mitochondrial function and high fat diet-induced insulin resistance. PhD Thesis 46. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Rat | Skeletal muscle |
| Tahara 2009 Free Radic Biol Med | 2009 | Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97. | LEAK ET OXPHOS | F N NS ROX S Gp | Isolated mitochondria | Rat | Heart Skeletal muscle Nervous system Liver Kidney |
| Giulivi 2008 Biochem J | 2008 | Giulivi C, Ross-Inta C, Horton AA, Luckhart S (2008) Metabolic pathways in Anopheles stephensi mitochondria. Biochem J 415:309-16. | LEAK OXPHOS | F N S Gp CIV Other combinations ROX | Isolated mitochondria | Human Rat Birds Hexapods | Skeletal muscle |
| Hoeks 2008 FEBS Lett | 2008 | Hoeks J, Briedรฉ JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16. | ROUTINE OXPHOS ET | F NS ROX | Isolated mitochondria | Rat | Skeletal muscle |
| Cervinkova 2008 Physiol Res | 2008 | Cervinkovรก Z, Rauchovรก H, Krivรกkovรก P, Drahota Z (2008) Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide. Physiol Res 57:133-6. | F N S | Isolated mitochondria | Liver | ||
| Gnaiger 2007 MitoPathways | 2007 |  Gnaiger E ed (2007) Mitochondrial pathways and respiratory control. 1st ed. Oroboros MiPNet Publications, Innsbruck:96 pp. ISBN 978-3-9502399-0-4. โ see 5th edition: Gnaiger 2020 BEC MitoPathways. | F N S Gp NS | ||||
| Wall 2006 Am J Physiol Heart Circ Physiol | 2006 | Wall JA, Wei J, Ly M, Belmont P, Martindale JJ, Tran D, Sun J, Chen WJ, Yu W, Oeller P, Briggs S, Gustafsson AB, Sayen MR, Gottlieb RA, Glembotski CC (2006) Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. Am J Physiol Heart Circ Physiol 291:H2462-72. https://doi.org/10.1152/ajpheart.01311.2005 | F S | ||||
| Toleikis 2005 Biosci Rep | 2005 | Toleikis A, Trumbeckaite S, Majiene D (2005) Cytochrome C effect on respiration of heart mitochondria: influence of various factors. Biosci Rep 25:387-97. | LEAK OXPHOS ET | F N S | Permeabilized tissue Isolated mitochondria | Human Rat Rabbit | Heart |
| Ponsot 2005 J Cell Physiol | 2005 | Ponsot E, Zoll J, N'guessan B, Ribera F, Lampert E, Richard R, Veksler V, Ventura-Clapier R, Mettauer B (2005) Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles. J Cell Physiol 203:479-86. | OXPHOS | F N Gp | Permeabilized tissue | Rat | Heart Skeletal muscle |
| Toogood 2004 J Biol Chem | 2004 | Toogood HS, van Thiel A, Basran J, Sutcliffe MJ, Scrutton NS, Leys D (2004) Extensive domain motion and electron transfer in the human electron transferring flavoprotein.medium chain Acyl-CoA dehydrogenase complex. J Biol Chem 279:32904-12. https://doi.org/10.1074/jbc.M404884200 | F | Enzyme | |||
| Rinaldo 2002 Annu Rev Physiol | 2002 | Rinaldo P, Matern D, Bennett MJ (2002) Fatty acid oxidation disorders. Annu Rev Physiol 64:477-502. https://doi.org/10.1146/annurev.physiol.64.082201.154705 | F | ||||
| Rasmussen 2001 Am J Physiol Endocrinol Metab | 2001 | Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7. | LEAK OXPHOS ET | F N S Gp NS | Isolated mitochondria | Human | Skeletal muscle |
| Himms-Hagen 2001 Exp Biol Med (Maywood) | 2001 | Himms-Hagen J, Harper ME (2001) Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis. Exp Biol Med (Maywood) 226:78-84. https://doi.org/10.1177/153537020122600204 | F | Skeletal muscle Fat | |||
| Curti 1997 Neurosci Lett | 1997 | Curti D, Rognoni F, Gasparini L, Cattaneo A, Paolillo M, Racchi M, Zani L, Bianchetti A, Trabucchi M, Bergamaschi S, Govoni S (1997) Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients. Neurosci Lett 236:13-6. | LEAK | F | Intact organism | Human | Heart |
| Moyes 1990 Am J Physiol | 1990 | Moyes CD, Buck LT, Hochachka PW (1990) Mitochondrial and peroxisomal fatty acid oxidation in elasmobranchs. Am J Physiol 258:R756-62. | OXPHOS | F | Isolated mitochondria | Fishes | Heart Skeletal muscle |
| Moyes 1989 J Exp Biol | 1989 | Moyes CD, Buck LT, Hochachka PW, Suarez RK (1989) Oxidative properties of carp red and white muscle. J Exp Biol 143:321-31. | OXPHOS | F N Gp | Isolated mitochondria | Skeletal muscle | |
| Vamecq 1987 Biochem J | 1987 | Vamecq J, Schepers L, Parmentier G, Mannaerts GP (1987) Inhibition of peroxisomal fatty acyl-CoA oxidase by antimycin A. Biochem J 248:603-7. | F ROX | Oxidase;biochemical oxidation | |||
| Gustafson 1986 J Biol Chem | 1986 | Gustafson WG, Feinberg BA, McFarland JT (1986) Energetics of beta-oxidation. Reduction potentials of general fatty acyl-CoA dehydrogenase, electron transfer flavoprotein, and fatty acyl-CoA substrates. J Biol Chem 261:7733-41 | F | Pig | |||
| Halestrap 1986 Biochem J | 1986 | Halestrap AP, Dunlop JL (1986) Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J 239:559-65. https://doi.org/10.1042/bj2390559 | LEAK OXPHOS ET | F N S DQ | Isolated mitochondria | Rat | Liver |
| Berry 1983 Eur J Biochem | 1983 | Berry MN, Gregory RB, Grivell AR, Wallace PG (1983) Compartmentation of fatty acid oxidation in liver cells. Eur J Biochem 131:215-22. doi: 10.1111/j.1432-1033.1983.tb07252.x | F | Intact cells | Rat | Liver | |
| Boveris 1973 Biochem J | 1973 | Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-16. | LEAK OXPHOS ET | F N S NS | Isolated mitochondria | Rat Birds | Heart |
| Koenig 1969 Biochem J | 1969 | Kรถnig T, Nicholls DG, Garland PB (1969) The inhibition of pyruvate and Ls(+)-isocitrate oxidation by succinate oxidation in rat liver mitochondria. Biochem J 114:589-96. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Rat | Heart Liver |
| Crane 1956 J Biol Chem | 1956 | Crane FL, Beinert H (1956) On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein. J Biol Chem 218:717-31. | F | ||||
| Geyer 1951 J Biol Chem | 1951 | Geyer RP, Cunningham M, Bendergast J (1951) Inhibition studies on radioactive fatty acid metabolism. J Biol Chem 188:185-91 | F S | Rat | Liver |
