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From Bioblast
- ...teins coded by the mtDNA. Most of the predicted pathogenic variants in the nDNA genes were restricted to a single continental population. The proportion of |area=mtDNA;mt-genetics, nDNA;cell genetics2 KB (281 words) - 14:54, 23 March 2016
- ...post-transcription are regulated by nuclear DNA (nDNA) genes we sought for nDNA genes whose expression pattern associated with the L haplogroup. Strikingl |area=mtDNA;mt-genetics, nDNA;cell genetics, Comparative MiP;environmental MiP2 KB (253 words) - 13:57, 25 August 2015
- ...a coactivator 1-alpha|PGC-1alpha]] involved in coordinated expression of [[nDNA]] and [[mtDNA]].409 bytes (45 words) - 15:56, 17 February 2016
- |abstract=Besides of the 23 chromosome pairs located in the nucleous (nDNA), the human genome also includes many DNA molecules placed in mitochondr ...ation and genetic particularities, mtDNA accumulates mutations faster than nDNA. Many of these mutations result into a serious disease. The construction of1 KB (193 words) - 14:20, 9 November 2016
- ...pressivity of nuclear DNA (nDNA)-encoded diseases, we combined in mice the nDNA Slc25a4<sup>-/-</sup> null mutation with a homoplasmic mtDNA ND6<sup>P25L</ |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression2 KB (334 words) - 12:21, 3 April 2019
- |area=Respiration, mt-Structure;fission;fusion, nDNA;cell genetics663 bytes (89 words) - 09:42, 20 August 2018
- ...al in suitable animal models. Here, we discuss two recent mouse models for nDNA-encoded complex I deficiency and their tissue-specific knock-outs.2 KB (252 words) - 13:27, 14 October 2023
- |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression Mfn1/2-null MEFs were also reduced, as well as mtDNA/nDNA ratio. On the other hand, Mfn2 knockout alone resulted in increased prolife7 KB (1,050 words) - 14:51, 13 November 2017
- |area=nDNA;cell genetics749 bytes (102 words) - 09:40, 20 August 2018
- ...ion, whereas nuclear NAD<sup>+</sup>/NADH ratio correlates with changes in nDNA and mtDNA transcription. Thus, mutations in the mtDNA cause distinct metabo |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics3 KB (404 words) - 15:29, 15 October 2019
- ...aminophylline, and also abolishes the action of aminophylline on the mtDNA/nDNA ratio and respiration rate, suggesting that the activation of CREB is requi2 KB (319 words) - 14:58, 12 January 2022
- ...sPD cybrid cells and sPD brain samples show very correlated regulation of nDNA and mtDNA ETC transcriptomes suggests similar bioenergetic physiologies. We2 KB (335 words) - 15:30, 22 August 2014
- ...roups was also significant (P = .002). In HIV-infected participants, mtDNA/nDNA in adipose tissue correlated with the level of activation (CD38+ /HLA-DR+)2 KB (325 words) - 15:13, 23 February 2020
- Human VSMC have increased nuclear (nDNA) and mitochondrial (mtDNA) damage and reduced repair capacity. A subset of |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics3 KB (362 words) - 15:33, 29 January 2018
- |area=nDNA;cell genetics, Genetic knockout;overexpression1 KB (141 words) - 15:30, 2 October 2019
- |additional=mtDNA, nDNA, populations1 KB (155 words) - 16:31, 26 March 2018
- |area=nDNA;cell genetics1 KB (178 words) - 22:09, 14 February 2020
- ...ers, unique to mtDNA, were identified by aligning segments of nuclear DNA (nDNA) to mtDNA, normalizing values to nuclear 16S rRNA, for a relative mtDNA cop |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics3 KB (393 words) - 14:59, 28 March 2018
- ...ption factors that coordinate the expression genes encoded by the nuclear (nDNA) and mitochondrial (mtDNA) genomes. However, little is known about the mole |area=mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression3 KB (411 words) - 09:44, 20 August 2018
- |area=nDNA;cell genetics1 KB (182 words) - 19:15, 25 June 2019
- |area=mtDNA;mt-genetics, nDNA;cell genetics2 KB (217 words) - 19:32, 1 April 2023
- ...estigate this hypothesis, we analyzed the relative importance of mtDNA and nDNA mutations in heart disease, the number one cause of mortality in the US. We |area=mtDNA;mt-genetics, nDNA;cell genetics3 KB (415 words) - 15:59, 4 September 2015
- ...nerative and neuromuscular diseases involving alterations in both nuclear (nDNA) and mitochondrial (mtDNA) DNA. Melatonin is a known powerful antioxidant a ...e, mitochondrial diseases, melatonin therapy, symbiont, ROS, NO, RNS, ATP, nDNA, mtDNA, Melatonin, cytochrome c, ADP, OXPHOS, Mitochondria, UCPs, TFAM, PTP3 KB (434 words) - 08:05, 21 February 2020
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine1 KB (212 words) - 16:08, 26 March 2019
- ...hase (CS) activity and tended (P ≤ 0.08) to have greater CS mRNA and mtDNA:nDNA ratio) than high-RFI steers. Hepatic expression ''SDHA'', ''UQCRC1'' and '' |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics, Exercise physiology;nutrition;life style3 KB (475 words) - 15:31, 2 January 2019
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression1 KB (176 words) - 10:15, 19 January 2022
- |area=Respiration, Instruments;methods, nDNA;cell genetics2 KB (205 words) - 22:07, 23 August 2021
- |area=nDNA;cell genetics, mt-Medicine2 KB (209 words) - 18:51, 16 January 2021
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression1 KB (196 words) - 16:55, 13 January 2020
- |area=nDNA;cell genetics2 KB (222 words) - 08:09, 13 September 2018
- |area=mtDNA;mt-genetics, nDNA;cell genetics1 KB (200 words) - 18:59, 16 January 2021
- |area=Respiration, nDNA;cell genetics, Patients2 KB (216 words) - 12:48, 21 June 2019
- ...iogenesis of a functional OXPHOS system further requires the assistance of nDNA-encoded OXPHOS assembly factors (chaperones), of which 35 are currently ide |area=Respiration, mt-Structure;fission;fusion, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine5 KB (639 words) - 11:17, 28 April 2017
- ...A) is less protected and has fewer reparation mechanisms than nuclear DNA (nDNA), and as such is more exposed to oxidative, mutation-inducing damage. This2 KB (263 words) - 21:45, 18 December 2023
- |area=nDNA;cell genetics2 KB (245 words) - 10:14, 9 November 2016
- |area=nDNA;cell genetics2 KB (236 words) - 01:50, 13 December 2021
- |area=nDNA;cell genetics2 KB (238 words) - 13:23, 27 July 2016
- |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Pharmacology;toxicology2 KB (222 words) - 12:32, 9 August 2019
- |area=nDNA;cell genetics2 KB (266 words) - 08:37, 8 January 2023
- |area=Respiration, nDNA;cell genetics2 KB (237 words) - 12:38, 16 February 2018
- |area=nDNA;cell genetics, Comparative MiP;environmental MiP2 KB (240 words) - 15:24, 17 February 2015
- |area=mtDNA;mt-genetics, nDNA;cell genetics, Comparative MiP;environmental MiP, Gender, Exercise physiolo2 KB (235 words) - 18:50, 16 January 2021
- |area=mt-Membrane, nDNA;cell genetics2 KB (282 words) - 18:55, 23 February 2019
- |area=Respiration, nDNA;cell genetics2 KB (249 words) - 10:16, 5 December 2022
- |area=Respiration, nDNA;cell genetics, Comparative MiP;environmental MiP2 KB (255 words) - 09:20, 9 November 2016
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine2 KB (235 words) - 11:06, 13 February 2015
- ...l biogenesis in Beas-2b cells through increasing mitochondrial mass, mtDNA/nDNA and the expression of cytochrome B. Importantly, we found that montelukast2 KB (254 words) - 12:11, 2 December 2019
- |area=Respiration, mt-Structure;fission;fusion, nDNA;cell genetics, Genetic knockout;overexpression, Exercise physiology;nutriti2 KB (252 words) - 11:11, 6 March 2018
- |area=mtDNA;mt-genetics, nDNA;cell genetics2 KB (253 words) - 17:15, 3 February 2016
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression2 KB (242 words) - 13:57, 15 October 2019
- |area=Respiration, mt-Membrane, nDNA;cell genetics2 KB (250 words) - 14:41, 13 November 2017
- ...ation, mt-Biogenesis;mt-density, mt-Structure;fission;fusion, mt-Membrane, nDNA;cell genetics, mt-Medicine, Patients2 KB (246 words) - 12:37, 16 February 2018
- |area=nDNA;cell genetics2 KB (287 words) - 16:42, 21 January 2024
- |area=nDNA;cell genetics, Exercise physiology;nutrition;life style2 KB (299 words) - 13:40, 20 October 2017
- |area=nDNA;cell genetics2 KB (278 words) - 13:52, 29 July 2016
- |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, mt-Medicine, Patients2 KB (290 words) - 22:38, 16 March 2019
- |area=Respiration, nDNA;cell genetics2 KB (256 words) - 11:48, 16 August 2021
- |area=Respiration, nDNA;cell genetics2 KB (276 words) - 15:01, 12 November 2018
- |area=mtDNA;mt-genetics, nDNA;cell genetics2 KB (279 words) - 16:06, 12 October 2016
- |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression2 KB (271 words) - 12:52, 16 February 2018
- ...mitochondrial biogenesis by increasing mitochondrial mass, elevating mtDNA/nDNA ratio, and stimulating the expression of cytochrome B, which were suppresse2 KB (256 words) - 05:24, 1 March 2020
- |area=nDNA;cell genetics2 KB (263 words) - 17:30, 25 February 2020
- ...uch as tumor suppressor and oncogenes that are encoded by the nuclear DNA (nDNA). For instance, the p53 tumor suppressor gene is frequently mutated and oft2 KB (288 words) - 17:04, 5 October 2023
- |area=Respiration, nDNA;cell genetics, mt-Medicine, Patients2 KB (270 words) - 14:00, 27 December 2021
- |area=Respiration, nDNA;cell genetics, Exercise physiology;nutrition;life style, mt-Medicine, mt-Aw2 KB (248 words) - 19:58, 20 November 2016
- |area=nDNA;cell genetics, mt-Medicine2 KB (312 words) - 14:54, 28 March 2018
- |area=Respiration, nDNA;cell genetics2 KB (269 words) - 15:49, 19 October 2021
- |area=Respiration, nDNA;cell genetics2 KB (265 words) - 15:33, 9 November 2016
- |area=Respiration, nDNA;cell genetics2 KB (299 words) - 13:32, 11 May 2020
- |area=Respiration, nDNA;cell genetics2 KB (279 words) - 16:00, 13 November 2017
- |area=nDNA;cell genetics2 KB (347 words) - 17:28, 23 March 2016
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression2 KB (282 words) - 11:46, 20 January 2020
- |area=Respiration, nDNA;cell genetics, mt-Medicine, Patients2 KB (272 words) - 15:50, 7 June 2022
- |area=mtDNA;mt-genetics, nDNA;cell genetics2 KB (286 words) - 13:40, 27 July 2016
- |area=Respiration, mt-Membrane, nDNA;cell genetics2 KB (271 words) - 21:42, 14 October 2020
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression2 KB (277 words) - 13:59, 27 March 2018
- |area=nDNA;cell genetics2 KB (282 words) - 01:51, 13 December 2021
- |area=nDNA;cell genetics, mt-Medicine2 KB (288 words) - 13:22, 23 October 2017
- |area=Respiration, nDNA;cell genetics2 KB (280 words) - 18:42, 22 July 2020
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, Patients2 KB (282 words) - 17:27, 9 November 2017
- |area=Respiration, nDNA;cell genetics2 KB (284 words) - 16:08, 30 October 2018
- |area=Respiration, nDNA;cell genetics, mt-Medicine2 KB (288 words) - 22:38, 1 December 2018
- |area=Respiration, nDNA;cell genetics2 KB (293 words) - 10:11, 24 April 2024
- |area=Respiration, mt-Biogenesis;mt-density, nDNA;cell genetics2 KB (282 words) - 08:46, 1 October 2018
- |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression2 KB (300 words) - 10:40, 9 November 2016
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression2 KB (329 words) - 13:44, 27 March 2018
- |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression2 KB (284 words) - 10:01, 8 November 2016
- |area=Respiration, nDNA;cell genetics, Exercise physiology;nutrition;life style2 KB (286 words) - 12:16, 24 June 2019
- |area=Respiration, nDNA;cell genetics2 KB (261 words) - 15:45, 16 August 2021
- |area=Respiration, nDNA;cell genetics2 KB (277 words) - 14:28, 26 April 2018
- |area=nDNA;cell genetics2 KB (291 words) - 17:07, 28 October 2018
- |area=nDNA;cell genetics2 KB (321 words) - 10:19, 2 February 2020
- |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression2 KB (295 words) - 16:33, 13 November 2017
- |area=Respiration, nDNA;cell genetics2 KB (298 words) - 18:36, 29 February 2020
- |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, Exercise physiology;nutriti2 KB (277 words) - 10:32, 29 July 2019
- |area=Respiration, nDNA;cell genetics, mt-Medicine, Pharmacology;toxicology2 KB (308 words) - 15:31, 10 October 2023
- |area=Respiration, nDNA;cell genetics, mt-Medicine2 KB (287 words) - 09:57, 8 November 2016
- |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine2 KB (313 words) - 13:45, 4 June 2018
- |area=mtDNA;mt-genetics, nDNA;cell genetics, Pharmacology;toxicology2 KB (288 words) - 12:25, 14 October 2015
- |area=Respiration, mt-Structure;fission;fusion, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression, Exercise physiology;nutriti2 KB (285 words) - 10:53, 27 March 2018