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  • ...teins coded by the mtDNA. Most of the predicted pathogenic variants in the nDNA genes were restricted to a single continental population. The proportion of |area=mtDNA;mt-genetics, nDNA;cell genetics
    2 KB (281 words) - 14:54, 23 March 2016
  • ...post-transcription are regulated by nuclear DNA (nDNA) genes we sought for nDNA genes whose expression pattern associated with the L haplogroup. Strikingl |area=mtDNA;mt-genetics, nDNA;cell genetics, Comparative MiP;environmental MiP
    2 KB (253 words) - 13:57, 25 August 2015
  • ...a coactivator 1-alpha|PGC-1alpha]] involved in coordinated expression of [[nDNA]] and [[mtDNA]].
    409 bytes (45 words) - 15:56, 17 February 2016
  • |abstract=Besides of the 23 chromosome pairs located in the nucleous (nDNA), the human genome also includes many DNA molecules placed in mitochondr ...ation and genetic particularities, mtDNA accumulates mutations faster than nDNA. Many of these mutations result into a serious disease. The construction of
    1 KB (193 words) - 14:20, 9 November 2016
  • ...pressivity of nuclear DNA (nDNA)-encoded diseases, we combined in mice the nDNA Slc25a4<sup>-/-</sup> null mutation with a homoplasmic mtDNA ND6<sup>P25L</ |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression
    2 KB (334 words) - 12:21, 3 April 2019
  • |area=Respiration, mt-Structure;fission;fusion, nDNA;cell genetics
    663 bytes (89 words) - 09:42, 20 August 2018
  • ...al in suitable animal models. Here, we discuss two recent mouse models for nDNA-encoded complex I deficiency and their tissue-specific knock-outs.
    2 KB (252 words) - 13:27, 14 October 2023
  • |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression Mfn1/2-null MEFs were also reduced, as well as mtDNA/nDNA ratio. On the other hand, Mfn2 knockout alone resulted in increased prolife
    7 KB (1,050 words) - 14:51, 13 November 2017
  • |area=nDNA;cell genetics
    749 bytes (102 words) - 09:40, 20 August 2018
  • ...ion, whereas nuclear NAD<sup>+</sup>/NADH ratio correlates with changes in nDNA and mtDNA transcription. Thus, mutations in the mtDNA cause distinct metabo |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics
    3 KB (404 words) - 15:29, 15 October 2019
  • ...aminophylline, and also abolishes the action of aminophylline on the mtDNA/nDNA ratio and respiration rate, suggesting that the activation of CREB is requi
    2 KB (319 words) - 14:58, 12 January 2022
  • ...sPD cybrid cells and sPD brain samples show very correlated regulation of nDNA and mtDNA ETC transcriptomes suggests similar bioenergetic physiologies. We
    2 KB (335 words) - 15:30, 22 August 2014
  • ...roups was also significant (P = .002). In HIV-infected participants, mtDNA/nDNA in adipose tissue correlated with the level of activation (CD38+ /HLA-DR+)
    2 KB (325 words) - 15:13, 23 February 2020
  • Human VSMC have increased nuclear (nDNA) and mitochondrial (mtDNA) damage and reduced repair capacity. A subset of |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics
    3 KB (362 words) - 15:33, 29 January 2018
  • |area=nDNA;cell genetics, Genetic knockout;overexpression
    1 KB (141 words) - 15:30, 2 October 2019
  • |additional=mtDNA, nDNA, populations
    1 KB (155 words) - 16:31, 26 March 2018
  • |area=nDNA;cell genetics
    1 KB (178 words) - 22:09, 14 February 2020
  • ...ers, unique to mtDNA, were identified by aligning segments of nuclear DNA (nDNA) to mtDNA, normalizing values to nuclear 16S rRNA, for a relative mtDNA cop |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics
    3 KB (393 words) - 14:59, 28 March 2018
  • ...ption factors that coordinate the expression genes encoded by the nuclear (nDNA) and mitochondrial (mtDNA) genomes. However, little is known about the mole |area=mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression
    3 KB (411 words) - 09:44, 20 August 2018
  • |area=nDNA;cell genetics
    1 KB (182 words) - 19:15, 25 June 2019
  • |area=mtDNA;mt-genetics, nDNA;cell genetics
    2 KB (217 words) - 19:32, 1 April 2023
  • ...estigate this hypothesis, we analyzed the relative importance of mtDNA and nDNA mutations in heart disease, the number one cause of mortality in the US. We |area=mtDNA;mt-genetics, nDNA;cell genetics
    3 KB (415 words) - 15:59, 4 September 2015
  • ...nerative and neuromuscular diseases involving alterations in both nuclear (nDNA) and mitochondrial (mtDNA) DNA. Melatonin is a known powerful antioxidant a ...e, mitochondrial diseases, melatonin therapy, symbiont, ROS, NO, RNS, ATP, nDNA, mtDNA, Melatonin, cytochrome c, ADP, OXPHOS, Mitochondria, UCPs, TFAM, PTP
    3 KB (434 words) - 08:05, 21 February 2020
  • |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine
    1 KB (212 words) - 16:08, 26 March 2019
  • ...hase (CS) activity and tended (P ≤ 0.08) to have greater CS mRNA and mtDNA:nDNA ratio) than high-RFI steers. Hepatic expression ''SDHA'', ''UQCRC1'' and '' |area=Respiration, mt-Biogenesis;mt-density, mtDNA;mt-genetics, nDNA;cell genetics, Exercise physiology;nutrition;life style
    3 KB (475 words) - 15:31, 2 January 2019
  • |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression
    1 KB (176 words) - 10:15, 19 January 2022
  • |area=Respiration, Instruments;methods, nDNA;cell genetics
    2 KB (205 words) - 22:07, 23 August 2021
  • |area=nDNA;cell genetics, mt-Medicine
    2 KB (209 words) - 18:51, 16 January 2021
  • |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression
    1 KB (196 words) - 16:55, 13 January 2020
  • |area=nDNA;cell genetics
    2 KB (222 words) - 08:09, 13 September 2018
  • |area=mtDNA;mt-genetics, nDNA;cell genetics
    1 KB (200 words) - 18:59, 16 January 2021
  • |area=Respiration, nDNA;cell genetics, Patients
    2 KB (216 words) - 12:48, 21 June 2019
  • ...iogenesis of a functional OXPHOS system further requires the assistance of nDNA-encoded OXPHOS assembly factors (chaperones), of which 35 are currently ide |area=Respiration, mt-Structure;fission;fusion, mtDNA;mt-genetics, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine
    5 KB (639 words) - 11:17, 28 April 2017
  • ...A) is less protected and has fewer reparation mechanisms than nuclear DNA (nDNA), and as such is more exposed to oxidative, mutation-inducing damage. This
    2 KB (263 words) - 21:45, 18 December 2023
  • |area=nDNA;cell genetics
    2 KB (245 words) - 10:14, 9 November 2016
  • |area=nDNA;cell genetics
    2 KB (236 words) - 01:50, 13 December 2021
  • |area=nDNA;cell genetics
    2 KB (238 words) - 13:23, 27 July 2016
  • |area=Respiration, mtDNA;mt-genetics, nDNA;cell genetics, Pharmacology;toxicology
    2 KB (222 words) - 12:32, 9 August 2019
  • |area=nDNA;cell genetics
    2 KB (266 words) - 08:37, 8 January 2023
  • |area=Respiration, nDNA;cell genetics
    2 KB (237 words) - 12:38, 16 February 2018
  • |area=nDNA;cell genetics, Comparative MiP;environmental MiP
    2 KB (240 words) - 15:24, 17 February 2015
  • |area=mtDNA;mt-genetics, nDNA;cell genetics, Comparative MiP;environmental MiP, Gender, Exercise physiolo
    2 KB (235 words) - 18:50, 16 January 2021
  • |area=mt-Membrane, nDNA;cell genetics
    2 KB (282 words) - 18:55, 23 February 2019
  • |area=Respiration, nDNA;cell genetics
    2 KB (249 words) - 10:16, 5 December 2022
  • |area=Respiration, nDNA;cell genetics, Comparative MiP;environmental MiP
    2 KB (255 words) - 09:20, 9 November 2016
  • |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression, mt-Medicine
    2 KB (235 words) - 11:06, 13 February 2015
  • ...l biogenesis in Beas-2b cells through increasing mitochondrial mass, mtDNA/nDNA and the expression of cytochrome B. Importantly, we found that montelukast
    2 KB (254 words) - 12:11, 2 December 2019
  • |area=Respiration, mt-Structure;fission;fusion, nDNA;cell genetics, Genetic knockout;overexpression, Exercise physiology;nutriti
    2 KB (252 words) - 11:11, 6 March 2018
  • |area=mtDNA;mt-genetics, nDNA;cell genetics
    2 KB (253 words) - 17:15, 3 February 2016
  • |area=Respiration, nDNA;cell genetics, Genetic knockout;overexpression
    2 KB (242 words) - 13:57, 15 October 2019

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