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Difference between revisions of "Template:Correction FADH2 and S-pathway"

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== Correction: FADH<sub>2</sub> and S-pathway ==
== Correction: FADH<sub>2</sub> and S-pathway ==


:::: NADH and FADH<sub>2</sub> are shown as substrates feeding electrons into the [[N-pathway]] and [[S-pathway]], respectively. This requires correction: "Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI,  reduced  FADH<sub>2</sub> is a product of Complex II with downstream electron flow from CII to Q" (page 48 in [[Gnaiger_2020_BEC_MitoPathways |Ref [2]]]. For details see Ref [2].
:::: '''FADH<sub>2</sub>''' is shown as the '''''substrate'' feeding electrons into the [[membrane-ETS]]''' in the [[S-pathway]]. This requires correction: "Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI,  reduced  FADH<sub>2</sub> is a product of Complex II with downstream electron flow from CII to Q" (page 48 in [[Gnaiger_2020_BEC_MitoPathways |Ref [2]]]. For details see Ref [2].


:::# Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
:::# Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
:::# Gnaiger E (2023) Complex II ambiguities ― FADH<sub>2</sub> in the electron transfer system. MitoFit Preprints 2023.3. https://doi.org/10.26124/mitofit:2023-0003
:::# Gnaiger E (2023) Complex II ambiguities ― FADH<sub>2</sub> in the electron transfer system. MitoFit Preprints 2023.3. https://doi.org/10.26124/mitofit:2023-0003

Revision as of 07:58, 30 March 2023

Correction: FADH2 and S-pathway

FADH2 is shown as the substrate feeding electrons into the membrane-ETS in the S-pathway. This requires correction: "Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI, reduced FADH2 is a product of Complex II with downstream electron flow from CII to Q" (page 48 in Ref [2]. For details see Ref [2].
  1. Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
  2. Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3. https://doi.org/10.26124/mitofit:2023-0003