Cookies help us deliver our services. By using our services, you agree to our use of cookies. More information

Difference between revisions of "Template:Correction FADH2 and S-pathway"

From Bioblast
(Created page with "== Correction: FADH<sub>2</sub> and S-pathway == :::Ā» Complex II ambiguities :::: A commonly found error on FADH<sub>2</sub> in the S-pathway requires correction. For cl...")
Ā 
Ā 
(19 intermediate revisions by the same user not shown)
Line 1: Line 1:
== Correction: FADH<sub>2</sub> and S-pathway ==
== Correction: FADH<sub>2</sub> and Complex II ==
:::Ā» [[Complex II ambiguities]]
[[File:Ambiguity alert.png|left|100px]]
:::: '''FADH<sub>2</sub>''' is shown as the '''''substrate''''' feeding electrons into '''Complex II''' (CII). This is wrong and requires correction - for details see Gnaiger (2024).


:::: A commonly found error on FADH<sub>2</sub> in the S-pathway requires correction. For clarification, see page 48 in [[Gnaiger_2020_BEC_MitoPathways |Gnaiger (2020)]]
::: Gnaiger E (2024) Complex II ambiguities ā€• FADH<sub>2</sub> in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - [[Gnaiger 2024 J Biol Chem |Ā»Bioblast linkĀ«]]
::::* Quote (p 48): "TheĀ  substrateĀ  ofĀ  CIIĀ  isĀ  succinate,Ā  whichĀ  isĀ  oxidizedĀ  formingĀ  fumarateĀ  while reducing flavin adenine dinucleotide FAD to FADH<sub>2</sub>, with further electron transfer to the quinone pool. Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI,Ā  reducedĀ  FADH<sub>2</sub> is a product of Complex II with downstream electron flow from CII to Q."


:::: Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
[[Category:Ambiguity crisis - CII and FADH2]]

Latest revision as of 09:49, 8 February 2024

Correction: FADH2 and Complex II

Ambiguity alert.png
FADH2 is shown as the substrate feeding electrons into Complex II (CII). This is wrong and requires correction - for details see Gnaiger (2024).
Gnaiger E (2024) Complex II ambiguities ā€• FADH2 in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - Ā»Bioblast linkĀ«