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Difference between revisions of "Template:Correction FADH2 and S-pathway"

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== Correction: FADH<sub>2</sub> and S-pathway ==
== Correction: FADH<sub>2</sub> and Complex II ==
[[File:Ambiguity alert.png|left|100px]]
:::: '''FADH<sub>2</sub>''' is shown as the '''''substrate''''' feeding electrons into '''Complex II''' (CII). This is wrong and requires correction - for details see Gnaiger (2024).


:::: NADH and FADH<sub>2</sub> are shown as substrates feeding electrons into the [[N-pathway]] and [[S-pathway]], respectively. This requires correction: "Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI,  reduced  FADH<sub>2</sub> is a product of Complex II with downstream electron flow from CII to Q" (page 48 in [[Gnaiger_2020_BEC_MitoPathways |Ref [2]]]. For details see Ref [2].
::: Gnaiger E (2024) Complex II ambiguities ― FADH<sub>2</sub> in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - [[Gnaiger 2024 J Biol Chem |»Bioblast link«]]


:::# Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
[[Category:Ambiguity crisis - CII and FADH2]]
:::# Gnaiger E (2023) Complex II ambiguities ― FADH<sub>2</sub> in the electron transfer system. MitoFit Preprints 2023.3. https://doi.org/10.26124/mitofit:2023-0003

Latest revision as of 09:49, 8 February 2024

Correction: FADH2 and Complex II

Ambiguity alert.png
FADH2 is shown as the substrate feeding electrons into Complex II (CII). This is wrong and requires correction - for details see Gnaiger (2024).
Gnaiger E (2024) Complex II ambiguities ― FADH2 in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - »Bioblast link«