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[[Image:Logo OROBOROS INSTRUMENTS.jpg|right|300px|link=http://www.oroboros.at|OROBOROS]]
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:: <big>'''OROBOROS INSTRUMENTS Corp'''</big>
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:: <big>'''high-resolution respirometry'''</big>
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:: Schöpfstr. 18
:: A-6020 Innsbruck, Austria
:: Email: mailto:[email protected]
:: '''» [http://www.oroboros.at www.oroboros.at]'''
:: '''» [[OROBOROS]], [[AT Innsbruck OROBOROS]]'''


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[[Image:O2k-Info.png|left|48px||link=http://http://www.oroboros.at/?O2k|Info OROBOROS]]
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'''A new Quality in Science - we develop, apply and distribute the [[Oxygraph-2k]]


unique for [http://www.oroboros.at/?O2k high-resolution respirometry] combined with [[O2k-Fluorescence_LED2-Module | O2k-Fluorometry]]'''


.. kindle the '''[http://www.oroboros.at/?houska-award_2011 Light in the Powerhouse of the Cells].'''
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A brief introduction to EBEC2024 from local organizer Erich Gnaiger, PhD.<br>
Join '''Mito & Chlora''' for presentations and discussions on the latest trends and research on all topics from bioenergetics to mitochondrial diseases.
[[File:Mito-and-Chlora_EBEC.png||link=http://www.ebec2024.org|right|150px|]]
'''[https://www.ebec2024.org EBEC2024]'''  
: '''Date:''' 2024 August 26 – 31<br>
: '''Location:''' Innsbruck, Austria<br>




[[Image:OdraNoel 7 End-of-cell.jpg|left|150px||link=http://www.mipart.at/index.php?id=odra-noel_mipart-posters|MiPArt - Mitochondria and Art]]
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<!--       STAY ALERT  and OROBOROS of the MONTH      -->
= Get connected =
<div style="margin:0.5em; background:#cedff2; font-family:inherit; font-size:120%; font-weight:bold; color:#000; padding:0.2em 0.4em;">Stay alert</div>
== Our service ==
<div id="mp-itn" style="padding:0.1em 0.6em;">{{Oroboros Ecosystem Agenda list}}</div>
[[Image:O2k-WorldWide.jpg|right|120px|link=http://www.bioblast.at/index.php/MiPNet_Reference_Laboratories|MiPNet Reference Laboratories]]
<big>'''Are you connected? - This is our network:'''</big>
::* Laboratories in the field of '''biomedicine''' and '''cell biology''': '''[[MiPNet Reference Laboratories | O2k-WorldWide MiPNet]]'''.
::* Scientists and students with an interest in '''mitochondrial physiology''': '''[http://www.oroboros.at/?high-resolution-respirometry Applications]'''.
::* Our experienced partners in development and production: '''[http://www.oroboros.at/index.php?id=partners OROBOROS Partners]'''.
::* Scientific expeditions: '''[http://www.oroboros.at/?Expeditions Science and adventure]'''.


<div style="margin:0.5em; background:#cedff2; font-family:inherit; font-size:120%; font-weight:bold; color:#000; padding:0.2em 0.4em;">Oroboros of the month</div>
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<big>'''What can we provide to you?'''</big>
<div style="margin:0.5em; background:#cedff2; font-family:inherit; font-size:120%; font-weight:bold; color:#000; padding:0.2em 0.4em;">Bioblast: About</div>
[[Image:O2k-Fluorescence LED2-Module.JPG|100px|left|link=link=http://www.bioblast.at/index.php/OroboPedia|OroboPedia]]
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::* '''O2k''': the instrument for measurement of '''cell respiration''' and key '''mitochondrial functions''': the '''[http://www.oroboros.at/?Oxygraph Oxygraph-2k]'''.
[[File:BB-Bioblast.jpg|left|85px|link=Bioblast:About]]'''Bioblast''' is an open access platform, including '''[[MitoPedia]]''' as a glossary and index for mitochondrial and chloroplast physiology, hosting '''[[MitoGlobal]]''', and supporting the journal '''[[Bioenergetics Communications]]''' and the '''Oroboros Ecosystem'''. </br>[[Bioblast:About|» More datails]]</div>
::* A concept complete with elaborated protocols, to get started and gain competence in the expanding field of '''bioenergetics''': '''[http://www.oroboros.at/?O2k-Protocols O2k-Protocols]'''.
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::* Introductory courses and advanced '''training''': '''[[OROBOROS O2k-Workshops]]'''.
<!--        NEXT AND PREVIOUS AGENDA        -->
::* High-resolution terminology - matching measurements at '''high-resolution''': '''[[MitoPedia Glossaries]]'''.
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[[Image:Power-O2k.png|left|240px|link=http://www.oroboros.at/?Power-O2k|Power-O2k]]
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== Our instruments ==
{{Next_oroboros_ecosystem_agenda}}
[[Image:O2.jpg|right|100px|link=http://www.oroboros.at/?Power-O2k|Dioxygen]]
<big>'''From the Oxygraph-2k to the Power-O2k'''</big>
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<big>'''O2'''k:</big> The '''Oxy'''graph-2k measures oxygen ([[Oxygen |dioxygen, '''O<sub>2</sub>''']]) as a gas dissolved in aqueous solutions. With the Oxy'''graph'''-2k, a graph is displayed not only of oxygen concentration over time, but of '''respiration''' (oxygen consumption, oxygen flux) of the biological sample. The Oxygraph-2k is not used for measurement of oxygen concentration in a tissue, but for high-resolution analysis of respiratory activity of biological samples transferred into the experimental chamber.
 
[[Image:O2k-Protocols.jpg|right|230px|link=http://http://www.bioblast.at/index.php/Gnaiger_2012_MitoPathways|MitoPathways]]
[[File:Pesta 2012 Methods Mol Biol Fig7A.jpg|left|250px|link=http://www.bioblast.at/index.php/Pesta_2012_Methods_Mol_Biol|Pesta and Gnaiger 2012]]
Specific substrate-uncoupler-inhibitor titration (SUIT) protocols are applied in studies of cell respiration or mitochondrial activity. In such experiments, quantitative information is obtained on selected [[Gnaiger 2012 MitoPathways |biochemical pathways]], particularly of the process of oxidative phosphorylation (OXPHOS) in mitochondria and bacteria. Comprehensive OXPHOS analysis leads us beyond the highly informative process of oxygen consumption, when high-resolution respirometry is combined with O2k-MultiSensor Modules to measure simultaneously the production of reactive oxygen species or mitochondrial membrane potential, nitric oxide production, acid-base balance or calcium with O2k-Fluorometry or ion selective electrodes. In the O2k, these bioenergetic parameters are always evaluated in combination with the measurement of oxygen concentration and respiration.
 
 
[[File:O2k-universe.jpg|right|240px|]]
* <big>O'''2k''':</big> The Oxygraph-2k is the '''2'''<sup>nd</sup> generation of our high-resolution respirometers. The first model was available since [http://www.oroboros.at/?Oroboros1992 1992]. Development of the new O'''2k''' started in '''2k''' (2000) and the first O'''2'''k was delivered in [http://www.oroboros.at/?Oroboros2002 '''2'''00'''2'''].
 
 
* <big>O2'''k''':</big> The Oxygraph-2k has two experimental chambers ('''k''': Kammern, German for chambers). [http://www.oroboros.at/?Oxygraph-2k Why 2 ml?]
 
 
* <big>'''Power-O2k''':</big> Several O2k units are operated simultaneously ('''P'''1, '''P'''2, ..) to combine high-resolution respirometry with [http://www.oroboros.at/?Power-O2k high-ouput].
 
 
== Our profile ==
<big>'''Know more about OROBOROS?'''</big>
[[Image:MitoPedia.jpg|right|120px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]]
::* A '''scientific''' company located in Austria and distributing the OROBOROS Oxygraph-2k WorldWide: '''[http://www.oroboros.at/?Oroboros-history The science company]'''.
::* We are '''specialists''' in instrumental development and applications in mitochondrial physiology: '''[http://www.oroboros.at/?O2k-Top10 Top 10 reasons]'''.
[[Image:OROBOROS-solo.png|left|40px|link=OROBOROS INSTRUMENTS]]
::* Way beyond an apparatus, we develop a concept '''connecting scientists''': '''[[MitoPedia | Bioblast MitoPedia]]'''.
::* OROBOROS: '''[http://www.oroboros.at/?Oroboros-logo The Logo]'''.
 
 
[[Image:OROBOROS-Team.jpg|left|300px|link=http://www.oroboros.at/?O2k-Team]]
 
<big>'''The OROBOROS-Team with visions ..'''</big>
[[Image:MitoGlobal.jpg|right|150px|link=http://www.bioblast.at/index.php/Mitochondrial_Global_Network|MitoGlobal]]
::* We share information from our '''Office''' and '''Mitochondrial Research Laboratory''': the '''[http://www.oroboros.at/?O2k-Team OROBOROS-Team]'''.
::* As a company of '''scientists''' we are supported by '''artists''': the '''[http://www.mipart.at/?MiPart-Gallery Mitochondrial Physiology Art Gallery - MiPArt]'''.
 
::* '''Open innovation''' - building greater ideas: the '''[[Mitochondrial Global Network | MitoGlobal Network]]'''.
 
<big>'''[[Gentle Science | Gentle Science shapes the world]]'''</big>
 
 
 
 
 
= Stay connected =
{{Mainpage orobopedia}}
[[Image:O2k-Info.png|left|55px||link=http://http://www.oroboros.at/?O2k|Info OROBOROS]]
<big>In an '''Open-Access''' approach, OROBOROS provides detailed information on the '''O2k and modular components''', the '''O2k-Manual''', '''O2k-Protocols''' and '''O2k-Publications''', the '''O2k-WorldWide MiPNet''', and '''OROBOROS O2k-Workshops'''.</big>


:: <big>'''» [[OroboPedia | O2k-Info in OroboPedia]]'''</big>
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<div style="margin:0.5em; background:#cef2e0; font-family:inherit; font-size:120%; font-weight:bold; color:#000; padding:0.2em 0.4em;">Last week and before</div>
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» [[Oroboros Ecosystem Agenda 2024 Archive]]  <br/>
» [[Oroboros Ecosystem Agenda 2023 Archive]]   </div>


:::: '''» [http://www.oroboros.at/?O2k-connected O2k-connected]
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Latest revision as of 16:17, 6 May 2024