Difference between revisions of "Q-junction"
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== Related pages | == Related MitoPedia pages == | ||
::* '''Electron transfer system, ETS''' | |||
:::: [[Electron transfer system]] | ::::» [[Electron transfer system]] | ||
:::: [[Q-junction]] | ::::» [[Q-junction]] | ||
::* '''Pathway control states''' | |||
:::: [[Pathway control state]] | ::::» [[Pathway control state]] | ||
::* '''Coupling control state ''E''''' | |||
:::: [[ETS capacity]] | ::::[[File:E.jpg |link=ETS capacity]] [[ETS capacity]] | ||
:::: [[Noncoupled respiration]] | ::::» [[Noncoupled respiration]] | ||
::::» [[Uncoupler#Is_respiration_uncoupled_-_noncoupled_-_dyscoupled.3F |Is respiration uncoupled - noncoupled - dyscoupled?]] |
Revision as of 16:14, 17 February 2017
Description
The Q-junction is a junction for convergent electron flow in the electron transfer system (ETS) from type N substrates and mt-matix dehydrogenases through Complex I (CI), from type F substrates and FA oxidation through electron-transferring flavoprotein complex (CETF), from succinate (S) through Complex II (CII), from glycoreophosphate (Gp) through glycerophosphate dehydrogenase complex (CGpDH), from choline through choline dehydrogenase, from dihydro-orotate through dihydro-orotate dehydrogenase, and other enzyme complexes into the Q-cycle (ubiquinol/ubiquinone), and further downstream to Complex III (CIII) and CIV. The concept of the Q-junction, with the N-junction and F-junction upstream, provides the rationale for defining pathway control states and categories of SUIT protocols.
Reference: Gnaiger 2009 Int J Biochem Cell Biol, Gnaiger 2014 MitoPathways
MitoPedia concepts:
MiP concept,
SUIT concept
MitoPedia methods:
Respirometry
MitoPedia topics:
Enzyme
Contributed by Gnaiger E 2010-08-15; edited 2016-02-12, 2016-03-28.
- Convergent NS-linked electron flow at the Q-junction, exerting an additive effect on flux, versus electron gaiting for separation of single N- and S-input pathways (upper panel: Gnaiger 2009; lower panel: Hatefi 1962 J Biol Chem-XLII). Modified Fig. 1.5 in Gnaiger 2014 MitoPathways.
Related MitoPedia pages
- Electron transfer system, ETS
- Pathway control states
- Coupling control state E