Semantic search
From Bioblast
| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Courtes 2019 Biomed Pharmacother | 2019 | Courtes AA, de Carvalho NR, Gonçalves DF, Hartmann DD, da Rosa PC, Dobrachinski F, Franco JL, de Souza DOG, Soares FAA (2019) Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats. Biomed Pharmacother 111:1438-46. | OXPHOS LEAK | N S NS ROX | Isolated mitochondria | Rat | Liver |
| Fiorenza 2019 FASEB J | 2019 | Fiorenza M, Lemminger AK, Marker M, Eibye K, Iaia FM, Bangsbo J, Hostrup M (2019) High-intensity exercise training enhances mitochondrial oxidative phosphorylation efficiency in a temperature-dependent manner in human skeletal muscle: implications for exercise performance. FASEB J 33:8976-89. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Mueller 2019 Neurochem Int | 2019 | Mueller TE, Nunes MEM, Rodrigues NR, Fontana BD, Hartmann DD, Franco JL, Rosemberg DB (2019) Neurochemical mechanisms underlying acute and chronic ethanol-mediated responses in zebrafish: The role of mitochondrial bioenergetics. Neurochem Int 131:104584. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Zebrafish | Nervous system |
| Bundgaard 2019 Sci Rep | 2019 | Bundgaard A, James AM, Gruszczyk AV, Martin J, Murphy MP, Fago A (2019) Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Sci Rep 9:2850. | LEAK OXPHOS | S | Isolated mitochondria | Mouse Reptiles | Heart |
| Azevedo 2019 Food Chem Toxicol | 2019 | Azevedo LF, Porto Dechandt CR, Cristina de Souza Rocha C, Hornos Carneiro MF, Alberici LC, Barbosa F Jr (2019) Long-term exposure to bisphenol A or S promotes glucose intolerance and changes hepatic mitochondrial metabolism in male Wistar rats. Food Chem Toxicol 132:110694. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue | Rat | Liver |
| Esselun 2019 Oxid Med Cell Longev | 2019 | Esselun C, Bruns B, Hagl S, Grewal R, Eckert GP (2019) Differential effects of silibinin A on mitochondrial function in neuronal PC12 and HepG2 liver cells. Oxid Med Cell Longev 2019:1652609. | LEAK OXPHOS ET | N S CIV NS | Permeabilized cells | Human Rat | Nervous system Liver |
| Gururaja Rao 2019 Cells | 2019 | Gururaja Rao S, Bednarczyk P, Towheed A, Shah K, Karekar P, Ponnalagu D, Jensen HN, Addya S, Reyes BAS, Van Bockstaele EJ, Szewczyk A, Wallace DC, Singh H (2019) BKCa (Slo) channel regulates mitochondrial function and lifespan in Drosophila melanogaster. Cells 8:E945. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Drosophila | |
| Li 2019 Int Urol Nephrol | 2019 | Li Z, Zhou J, Li Y, Yang F, Lian X, Liu W (2019) Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells. Int Urol Nephrol 51:1059-70. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
| Shirakawa 2019 Sci Rep | 2019 | Shirakawa R, Yokota T, Nakajima T, Takada S, Yamane M, Furihata T, Maekawa S, Nambu H, Katayama T, Fukushima A, Saito A, Ishimori N, Dela F, Kinugawa S, Anzai T (2019) Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients. Sci Rep 9:14709. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Human | Blood cells |
| Rawat 2019 J Mol Biol | 2019 | Rawat S, Anusha V, Jha M, Sreedurgalakshmi K, Raychaudhuri S (2019) Aggregation of respiratory complex subunits marks the onset of proteotoxicity in proteasome inhibited cells. J Mol Biol 431:996-1015. | OXPHOS LEAK | N S CIV ROX | Permeabilized cells | Mouse | Nervous system Other cell lines |
| Gonzalez-Armenta 2019 J Nutr | 2019 | Gonzalez-Armenta JL, Gao Z, Appt SE, Vitolins MZ, Michalson KT, Register TC, Shively CA, Molina AJA (2019) Skeletal muscle mitochondrial respiration is elevated in female cynomolgus macaques fed a western compared with a mediterranean diet. J Nutr 149:1493-502. | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized tissue | Other mammals | Skeletal muscle |
| Kirby 2019 Comp Biochem Physiol C Toxicol Pharmacol | 2019 | Kirby AR, Cox GK, Nelson D, Heuer RM, Stieglitz JD, Benetti DD, Grosell M, Crossley DA 2nd (2019) Acute crude oil exposure alters mitochondrial function and ADP affinity in cardiac muscle fibers of young adult Mahi-mahi (Coryphaena hippurus). Comp Biochem Physiol C Toxicol Pharmacol 218:88-95. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Heart |
| Altinok 2019 J Cell Physiol | 2019 | Altinok O, Poggio JL, Stein DE, Bowne WB, Shieh AC, Snyder NW, Orynbayeva Z (2019) Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria. J Cell Physiol 235:2569-81. | LEAK OXPHOS | N S | Isolated mitochondria | Human | Other cell lines |
| Kunz 2019 Am J Physiol Endocrinol Metab | 2019 | Kunz HE, Dasari S, Lanza IR (2019) EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver. Am J Physiol Endocrinol Metab 317:E460-E472. | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle Liver |
| Fang 2019 Nat Commun | 2019 | Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA (2019) NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome. Nat Commun 10:5284. | LEAK OXPHOS | F N S CIV ROX | Homogenate | Mouse | Heart Nervous system Liver |
| Tufi 2019 Cell Rep | 2019 | Tufi R, Gleeson TP, von Stockum S, Hewitt VL, Lee JJ, Terriente-Felix A, Sanchez-Martinez A, Ziviani E, Whitworth AJ (2019) Comprehensive genetic characterization of mitochondriaasl Ca2+ uniporter components reveals their different physiological requirements in vivo. https://doi.org/10.1016/j.celrep.2019.04.033 | OXPHOS | N S | Homogenate | Drosophila | |
| Garcia-Roche 2019 PLoS One | 2019 | García-Roche M, Casal A, Mattiauda DA, Ceriani M, Jasinsky A, Mastrogiovanni M, Trostchansky A, Carriquiry M, Cassina A, Quijano C (2019) Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation. PLoS One 14:e0213780. | LEAK OXPHOS ET | N S NS ROX | Intact cells | Bovines | Liver |
| Rodinova 2019 Dis Model Mech | 2019 | Rodinova M, Krizova J, Stufkova H, Bohuslavova B, Askeland G, Dosoudilova Z, Juhas S, Juhasova J, Ellederova Z, Zeman J, Eide L, Motlik J, Hansikova H (2019) Deterioration of mitochondrial bioenergetics and ultrastructure impairment in skeletal muscle of a transgenic minipig model in the early stages of Huntington's disease. Dis Model Mech 12:dmm038737. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Pig | Skeletal muscle |
| Anton 2019 Front Physiol | 2019 | Anton L, DeVine A, Polyak E, Olarerin-George A, Brown AG, Falk MJ, Elovitz MA (2019) HIF-1α stabilization increases miR-210 eliciting first trimester extravillous trophoblast mitochondrial dysfunction. Front Physiol 10:699. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Genital |
| Naszai 2019 Sci Rep | 2019 | Nászai A, Terhes E, Kaszaki J, Boros M, Juhász L (2019) Ca(2+)N it be measured? Detection of extramitochondrial calcium movement with high-resolution FluoRespirometry. Sci Rep 9:19229. | LEAK OXPHOS | N S NS ROX | Isolated mitochondria | Rat | Liver |
| Sundstroem 2019 Acta Neuropathol Commun | 2019 | Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen F (2019) Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis. Acta Neuropathol Commun 7:55. | ET LEAK | N S NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
| Kumar 2019 Free Radic Biol Med | 2019 | Kumar A, Davuluri G, Welch N, Kim A, Gangadhariah M, Allawy A, Priyadarshini A, McMullen MR, Sandlers Y, Willard B, Hoppel CL, Nagy LE, Dasarathy S (2019) Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy. Free Radic Biol Med 145:284-99. | LEAK ROUTINE OXPHOS ET | F N S DQ CIV NS ROX | Permeabilized cells Permeabilized tissue Intact cells | Mouse | Skeletal muscle |
| Detaille 2019 PLoS One | 2019 | Detaille D, Pasdois P, Sémont A, Dos Santos P, Diolez P (2019) An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals. PLoS One 14:e0216385. | LEAK OXPHOS | N S NS ROX | Isolated mitochondria | Rat | Heart |
| Huerta 2019 Aquat Toxicol | 2019 | Huerta B, Chung-Davidson YW, Bussy U, Zhang Y, Bazil JN, Li W (2019) Sea lamprey cardiac mitochondrial bioenergetics after exposure to TFM and its metabolites. Aquat Toxicol 219:105380. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Fishes | Heart |
| Brunetta 2019 J Funct Foods | 2019 | Brunetta HS, de Paula GC, Fritzen M, Cecchini MS, dos Santos GJ, Nazari EM, Rafacho A, de Bem AF, Nunes EA (2019) Leucine increases muscle mitochondrial respiration and attenuates glucose intolerance in diet-induced obesity in Swiss mice. J Funct Foods 62:103544. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Gonzalez-Mariscal 2019 FASEB J | 2019 | González-Mariscal I, Montoro RA, O'Connell JF, Kim Y, Gonzalez-Freire M, Liu QR, Alfaras I, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Hardivillé S, Ghosh P, Egan JM (2019) Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism. FASEB J 33:5850-63. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Belosludtsev 2019 Biochim Biophys Acta Biomembr | 2019 | Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2019) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta Biomembr 1861:288-97. | LEAK OXPHOS | N S NS | Isolated mitochondria | Rat | Liver |
| Pharaoh 2019 Mol Neurobiol | 2019 | Pharaoh G, Owen D, Yeganeh A, Premkumar P, Farley J, Bhaskaran S, Ashpole N, Kinter M, Van Remmen H, Logan S (2019) Disparate central and peripheral effects of circulating IGF-1 deficiency on tissue mitochondrial function. Mol Neurobiol 57:1317-31. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue Isolated mitochondria Intact cells | Mouse | Skeletal muscle Nervous system Fat |
| Thomas 2019 Redox Biol | 2019 | Thomas NO, Shay KP, Hagen TM (2019) Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I. Redox Biol 22:101155. | LEAK OXPHOS ET | N S NS ROX | Intact cells | Rat | Liver |
| Shrum 2019 Biomolecules | 2019 | Shrum S, Rusch NJ, MacMillan-Crow LA (2019) Specific BK channel activator NS11021 protects rat renal proximal tubular cells from cold storage-induced mitochondrial injury in vitro. Biomolecules 9:E825. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Rat | Kidney |
| Reda 2019 Sci Rep | 2019 | Reda A, Refaat A, Abd-Rabou AA, Mahmoud AM, Adel M, Sabet S, Ali SS (2019) Role of mitochondria in rescuing glycolytically inhibited subpopulation of triple negative but not hormone-responsive breast cancer cells. Sci Rep 9:13748. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
| Skrivergaard 2019 Viruses | 2019 | Skrivergaard S, Jensen MS, Rolander TB, Nguyen TBN, Bundgaard A, Nejsum LN, Martensen PM (2019) The cellular localization of the p42 and p46 oligoadenylate synthetase 1 isoforms and their impact on mitochondrial respiration. Viruses 11:E1122. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Other cell lines HeLa |
| D'Amico 2019 Mol Cell | 2019 | D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J (2019) The RNA-binding protein PUM2 impairs mitochondrial dynamics and mitophagy during aging. Mol Cell 73:775-87. | OXPHOS | S NS ROX | Homogenate | Mouse | Skeletal muscle |
| Woodman 2019 Cardiovasc Res | 2019 | Woodman AG, Mah R, Keddie DL, Noble RMN, Holody CD, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2019) Perinatal iron deficiency and a high salt diet cause long-term kidney mitochondrial dysfunction and oxidative stress. Cardiovasc Res 116:183-92. | LEAK OXPHOS ET | N S CIV NS | Homogenate | Rat | Kidney |
| Long 2019 Methods Mol Biol | 2019 | Long Q, Huang L, Huang K, Yang Q (2019) Assessing mitochondrial bioenergetics in isolated mitochondria from mouse heart tissues using Oroboros Oxygraph-2k. Methods Mol Biol 1966:237-46. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Heart |
| Krylova 2019 Mitochondrion | 2019 | Krylova TD, Sheremet NL, Tabakov VY, Lyamzaev KG, Itkis YS, Tsygankova PG, Andreeva NA, Shmelkova MS, Nevinitsyna TA, Kadyshev VV, Zakharova EY (2019) Three rare pathogenic mtDNA substitutions in LHON patients with low heteroplasmy. Mitochondrion 50:139-144. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Latham 2019 J Anim Sci | 2019 | Latham CM, Fenger CK, White SH (2019) Rapid Communication: Differential skeletal muscle mitochondrial characteristics of weanling racing-bred horses. J Anim Sci [Epub ahead of print]. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
| Cesnekova 2019 Thesis | 2019 | Cesnekova J (2019) Functional characterization of LACE1 APTase and mitochondrial AAA proteases YME1L and AFG3L2 in mitochondrial protein homeostasis. PhD Thesis 133. | OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | HEK |
| Dall 2019 J Biol Chem | 2019 | Dall M, Trammell SAJ, Asping M, Hassing AS, Agerholm M, Vienberg SG, Gillum MP, Larsen S, Treebak JT (2019) Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity. J Biol Chem 294:13304-26. | LEAK OXPHOS ET | F N S | Intact cells | Mouse | Liver |
| Dilberger 2019 Oxid Med Cell Longev | 2019 | Dilberger B, Baumanns S, Schmitt F, Schmiedl T, Hardt M, Wenzel U, Eckert GP (2019) Mitochondrial oxidative stress impairs energy metabolism and reduces stress resistance and longevity of C. elegans. Oxid Med Cell Longev 2019:6840540. | LEAK ROUTINE ET | N S CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
| Garrido-Maraver 2019 Cell Death Dis | 2019 | Garrido-Maraver J, Celardo I, Costa AC, Lehmann S, Loh SHY, Martins LM (2019) Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin. Cell Death Dis 10:288. | OXPHOS ET | N S | Permeabilized tissue | Drosophila | |
| Dannheisig 2019 Cells | 2019 | Dannheisig DP, Beck E, Calzia E, Walther P, Behrends C, Pfister AS (2019) Loss of Peter Pan (PPAN) affects mitochondrial homeostasis and autophagic flux. Cells 8:E894. | LEAK ROUTINE ET | N S CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
| Nold 2019 Psychoneuroendocrinology | 2019 | Nold V, Sweatman C, Karabatsiakis A, Böck C, Bretschneider T, Lawless N, Fundel-Clemens K, Kolassa IT, Allers KA (2019) Activation of the kynurenine pathway and mitochondrial respiration to face allostatic load in a double-hit model of stress. Psychoneuroendocrinology 107:148-59. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
| Perry 2019 J Mol Cell Cardiol | 2019 | Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA (2019) Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury. J Mol Cell Cardiol 135:160-171. | LEAK OXPHOS | N S ROX | Isolated mitochondria Permeabilized cells | Rat | Heart |
| Hedges 2019 Comp Biochem Physiol A Mol Integr Physiol | 2019 | Hedges CP, Wilkinson RT, Devaux JBL, Hickey AJR (2019) Hymenoptera flight muscle mitochondrial function: Increasing metabolic power increases oxidative stress. Comp Biochem Physiol A Mol Integr Physiol 230:115-21. | OXPHOS ET LEAK | N S Gp CIV NS ROX | Permeabilized tissue | Other invertebrates | Skeletal muscle |
| Robinson 2019 Am J Physiol Cell Physiol | 2019 | Robinson MM, Sather BK, Burney ER, Ehrlicher SE, Stierwalt HD, Franco MC, Newsom SA (2019) Robust intrinsic differences in mitochondrial respiration and H2O2 emission between L6 and C2C12 cells. Am J Physiol Cell Physiol 317:C339-C347. | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Mouse Rat | Skeletal muscle |
| Chiba 2019 J Am Soc Nephrol | 2019 | Chiba T, Peasley KD, Cargill KR, Maringer KV, Bharathi SS, Mukherjee E, Zhang Y, Holtz A, Basisty N, Yagobian SD, Schilling B, Goetzman ES, Sims-Lucas S (2019) Sirtuin 5 regulates proximal tubule fatty acid oxidation to protect against AKI. J Am Soc Nephrol 30:2384-98. | OXPHOS | N S | Homogenate | Mouse | Kidney |
| Mayeuf-Louchart 2019 Cell Rep | 2019 | Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H (2019) Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation. Cell Rep 29:1410-18. | LEAK OXPHOS | F N S NS | Permeabilized cells | Mouse | Fat |
| Bianco 2019 PLoS One | 2019 | Bianco M, Lopes JA, Beiral HJV, Filho JDD, Frankenfeld SP, Fortunato RS, Gattass CR, Vieyra A, Takiya CM (2019) The contralateral kidney presents with impaired mitochondrial functions and disrupted redox homeostasis after 14 days of unilateral ureteral obstruction in mice. PLoS One 14:e0218986. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Kidney |
| Ferreira 2019 EMBO J | 2019 | Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O (2019) Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. EMBO J 38:e102155. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart Liver |
| Yan 2019 Int Immunopharmacol | 2019 | Yan M, Yu Y, Mao X, Feng J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:61-7. | LEAK OXPHOS | S | Isolated mitochondria | Mouse | Liver |
| Lozano 2019 Oxid Med Cell Longev | 2019 | Lozano O, Lázaro-Alfaro A, Silva-Platas C, Oropeza-Almazán Y, Torres-Quintanilla A, Bernal-Ramírez J, Alves-Figueiredo H, García-Rivas G (2019) Nanoencapsulated quercetin improves cardioprotection during hypoxia-reoxygenation injury through preservation of mitochondrial function. Oxid Med Cell Longev 2019:7683051. | ET | S | Permeabilized cells | Rat | Skeletal muscle |
| Berg 2019 Front Physiol | 2019 | Berg J, Undebakke V, Rasch-Halvorsen Ø, Aakerøy L, Sandbakk Ø, Tjønna AE (2019) Comparison of mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country skiers and physically active controls. Front Physiol 10:365. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Bittel 2019 Diabetologia | 2019 | Bittel AJ, Bittel DC, Mittendorfer B, Patterson BW, Okunade AL, Yoshino J, Porter LC, Abumrad NA, Reeds DN, Cade WT (2019) A single bout of resistance exercise improves postprandial lipid metabolism in overweight/obese men with prediabetes. Diabetologia 63:611-23. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Mazaki 2019 Biochem Biophys Res Commun | 2019 | Mazaki Y, Takada S, Nio-Kobayashi J, Maekawa S, Higashi T, Onodera Y, Sabe H (2019) Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60 cells. Biochem Biophys Res Commun 513:708-13. | OXPHOS | N S | Permeabilized cells | Human | Blood cells |
| De Moura Escobar 2019 Toxicol In Vitro | 2019 | de Moura Escobar SJ, Simone M, de Oliveira Ribeiro CA, Martinez GR, Winnischofer SMB, Witting PK, Rocha MEM (2019) Cytotoxic effects of 4'-hydroxychalcone on human neuroblastoma cells (SH-SY5Y). Toxicol In Vitro 61:104640. | LEAK OXPHOS | N S ROX | Permeabilized cells | Human | Neuroblastoma |
| Electron-transfer-pathway state | 2019 | Gnaiger E (2019) ET-pathway states. Mitochondr Physiol Network 2019-06-11 (last edit since 2016-11-08). | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria SMP | ||
| Weinstein 2019 bioRxiv | 2019 | Weinstein RN, Crawford DL (2019) Effect of EBV-transformation on oxidative phosphorylation physiology in human cell lines. bioRxiv doi: https://doi.org/10.1101/2019.12.16.878025 . | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines Lymphocyte |
| Crescenzo 2019 Mol Neurobiol | 2019 | Crescenzo R, Spagnuolo MS, Cancelliere R, Iannotta L, Mazzoli A, Gatto C, Iossa S, Cigliano L (2019) Effect of initial aging and high-fat/high-fructose diet on mitochondrial bioenergetics and oxidative status in rat brain. Mol Neurobiol 56:7651-63. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
| Miranda-Silva 2019 Acta Physiologica | 2019 | Miranda-Silva D, Wüst RCI, Conceição G, Gonçalves-Rodrigues P, Gonçalves N, Gonçalves A, Kuster DWD, Leite-Moreira AF, van der Velden J, de Sousa Beleza JM, Magalhães J, Stienen GJM, Falcão-Pires I (2019) Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction. Acta Physiol e13378. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact organ Permeabilized tissue Isolated mitochondria | Rat | Heart |
| Ahn 2019 J Cachexia Sarcopenia Muscle | 2019 | Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, Griffin TM, Freeman WM, Richardson A, Brooks SV, Van Remmen H (2019) Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fiber branching. J Cachexia Sarcopenia Muscle 10:411-28. | OXPHOS LEAK | N S CIV NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
| Havird 2019 Mitochondrion | 2019 | Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2019) Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function? Mitochondrion 49:1-11. | LEAK OXPHOS | N S CIV NS ROX | Isolated mitochondria | Plants | |
| Chroeis 2019 Basic Clin Pharmacol Toxicol | 2019 | Chroeis KM, Larsen S, Pedersen JS, Rygg MO, Boilsen AEB, Bendtsen F, Dela F (2019) Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue. https://doi.org/10.1111/bcpt.13304 | LEAK OXPHOS | N S ROX | Intact cells | Human | Liver |
| Campos 2019 Thesis | 2019 | Campos DF (2019) Os peixes amazônicos vivem perto dos seus limites térmicos? O efeito das mudanças climáticas sobre a ecofisiologia de peixes de Igarapé da Amazônia Central. PhD Thesis 106. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells | Fishes | Lung;gill |
| Devaux 2019 J Exp Biol | 2019 | Devaux JBL, Hickey AJR, Renshaw GMC (2019) Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation. J Exp Biol 222:jeb191353. | LEAK ROUTINE OXPHOS ET | N S NS | Homogenate | Fishes | Nervous system |
| Wang H 2019 J Biol Chem | 2019 | Wang H, Lu J, Kulkarni S, Zhang W, Gorka JE, Mandel JA, Goetzman ES, Prochownik EV (2019) Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts. J Biol Chem 294:5466-86. | ROUTINE OXPHOS ET | F N S NS | Permeabilized cells Isolated mitochondria Intact cells | Rat | Fibroblast |
| Heden 2019 Sci Adv | 2019 | Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K (2019) Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv 5:eaax8352. | LEAK OXPHOS | F N S DQ CIV NS ROX | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
| Svab 2019 Neurochem Res | 2019 | Svab G, Doczi J, Gerencser AA, Ambrus A, Gallyas F, Sümegi B, Tretter L (2019) The mitochondrial targets of neuroprotective drug vinpocetine on primary neuron cultures, brain capillary endothelial cells, synaptosomes, and brain mitochondria. Neurochem Res 44:2435-47. | LEAK OXPHOS ET | N S | Isolated mitochondria Intact cells | Guinea pig | Nervous system |
| Zhu 2019 Aging Cell | 2019 | Zhu B, Li Y, Xiang L, Zhang J, Wang L, Guo B, Liang M, Chen L, Xiang L, Dong J, Liu M, Mei W, Li H, Xiang G (2019) Alogliptin improves survival and health of mice on a high-fat diet. Aging Cell 18:e12883. | LEAK OXPHOS ET | N NS S ROX | Isolated mitochondria | Mouse | Liver |
| Gregg 2019 J Biol Chem | 2019 | Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ (2019) Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at Complex I in pancreatic β-cells. J Biol Chem 294:4656-66. | OXPHOS ET LEAK | N S NS ROX | Permeabilized tissue | Mouse | Islet cell;pancreas;thymus |
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| MiPNet21.06 SUIT RP | 2018-06-25 | SUIT reference protocol for OXPHOS analysis by high-resolution respirometry. | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | ||
| Komlodi 2018 J Bioenerg Biomembr | 2018 | Komlódi T, Geibl FF, Sassani M, Ambrus A, Tretter L (2018) Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr 50:355-365 | LEAK | S Gp | Isolated mitochondria | Guinea pig | Heart Nervous system |
| Jang 2018 J Med Toxicol | 2018 | Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Blood cells |
| Ost 2018 Curr Opin Clin Nutr Metab Care | 2018 | Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells | Blood cells Platelet Skeletal muscle Liver Fat | |
| Budai 2018 Br J Surg | 2018 | Budai A, Horváth G, Tretter L, Radák Z, Koltai E, Bori Z, Torma F, Lukáts Á, Röhlich P, Szijártó A, Fülöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31. | OXPHOS | N S | Isolated mitochondria | Rat | Liver |
| Holloway 2018 Cell Rep | 2018 | Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC (2018) Age-associated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Logan 2018 Thesis | 2018 | Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Zebrafish | Skeletal muscle |
| Lo 2018 Am J Physiol Renal Physiol | 2018 | Lo S, MacMillan-Crow LA, Parajuli N (2018) Renal cold storage followed by transplantation impairs proteasome function and subsequently mitochondrial protein homeostasis. Am J Physiol Renal Physiol 316:F42-F53. | OXPHOS LEAK | N S ROX | Permeabilized cells | Rat | Kidney Other cell lines |
| Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Human | Lung;gill Fibroblast |
| Weisz 2018 Hum Mol Genet | 2018 | Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106. | OXPHOS ET LEAK | N S NS ROX | Isolated mitochondria | Drosophila | Skeletal muscle |
| Menezes-Filho 2018 Biochim Biophys Acta Bioenerg | 2018 | Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35. | OXPHOS ET | N S | Isolated mitochondria | Mouse | Liver |
| Lu 2018 Cell Rep | 2018 | Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
| Tripodi 2018 Biochim Biophys Acta Mol Cell Res | 2018 | Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13. | OXPHOS LEAK | N S | Isolated mitochondria | Saccharomyces cerevisiae | |
| Wuest 2018 Cell Metab | 2018 | Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T (2018) Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster. Cell Metab 27:1026-39. | OXPHOS | N S CIV | Intact cells | Mouse | Skeletal muscle |
| Papadimitriou 2018 Thesis | 2018 | Papadimitriou ID (2018) The influence of ACTN3 R577X genotype on performance and muscle adaptations to a single bout of exercise . PhD Thesis 125. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Chung 2018 J Exp Biol | 2018 | Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458. | LEAK OXPHOS ET | F N S CIV NS ROX | Isolated mitochondria | Fishes | Liver |
| Woodman 2018 FASEB J | 2018 | Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Rat | Liver Kidney |
| Bricambert 2018 Nat Commun | 2018 | Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092. | LEAK OXPHOS ET | N S | Homogenate | Mouse | Liver |
| Park 2018 J Clin Invest | 2018 | Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711. | OXPHOS ET LEAK | F N S | Permeabilized tissue | Mouse | Fat |
| Van der Pluijm 2018 Cardiovasc Res | 2018 | van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93. | OXPHOS | N S NS ROX | Homogenate | Mouse | Skeletal muscle |
| Tosi 2018 J Bioenerg Biomembr | 2018 | Tosi I, Art T, Cassart D, Farnir F, Ceusters J, Serteyn D, Lemieux H, Votion DM (2018) Altered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy. J Bioenerg Biomembr 50:379-90. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
| Singh 2018 Arch Toxicol | 2018 | Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504. | OXPHOS LEAK | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Garcia-Roche 2018 Redox Biol | 2018 | García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12. | LEAK OXPHOS ET | N NS ROX S | Permeabilized tissue | Rat Bovines | Liver |
| Musi 2018 Aging Cell | 2018 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | F N S NS | Homogenate | Mouse | Nervous system |
| Lal 2018 Springer | 2018 | Lal MA (2018) Respiration. In: Bhatla SC, Lal MA (eds) Plant physiology, development and metabolism. Springer, Singapore:253-314. https://doi.org/10.1007/978-981-13-2023-1_7 | S Gp | ||||
| Rodriguez-Nuevo 2018 EMBO J | 2018 | Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Mayer 2018 Endocrinology | 2018 | Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26. | OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Liver |
| Hoffmann 2018 Sci Rep | 2018 | Hoffmann C, Höckele S, Kappler L, Hrabĕ de Angelis M, Häring HU, Weigert C (2018) The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells. Sci Rep 8:737. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Human | Skeletal muscle |
| Tillmans 2018 Thesis | 2018 | Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92. | LEAK ROUTINE ET | N S NS ROX | Intact cells Permeabilized cells | Human | Other cell lines Lymphocyte |
| Trewin 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H2O2 release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Friederich 2018 Nat Commun | 2018 | Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human Fungi | Fibroblast |
| Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
| Seite 2018 Sci Rep | 2018 | Seite S, Mourier A, Camougrand N, Salin B, Figueiredo-Silva AC, Fontagne-Dicharry S, Panserat S, Seiliez I (2018) Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss). Sci Rep 8:10151. | N S CIV NS ROX | Homogenate | Fishes | Liver | |
| Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | ROUTINE OXPHOS ET LEAK | N S | Permeabilized cells Intact cells | Mouse | Lymphocyte |
| Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
| Van Erp 2018 Sci Rep | 2018 | Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405. | OXPHOS ET | F N S NS | Isolated mitochondria | Rat | Liver Kidney |
| Ale-Agha 2018 PLOS Biol | 2018 | Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J (2018) CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. PLOS Biol 6:e2004408. | OXPHOS | N S CIV | Isolated mitochondria | Mouse | Heart |
| Burtscher 2018 Front Mol Neurosci | 2018 | Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
| Astrakhanova 2018 Sovrem Tekhnologii Med | 2018 | Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94. | OXPHOS LEAK | N S | Isolated mitochondria | Mouse | Nervous system |
| Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | LEAK ROUTINE OXPHOS ET | F S Gp | Permeabilized cells Intact cells | Human | Other cell lines Fibroblast |
| Monzio Compagnoni 2018 Biochim Biophys Acta Mol Basis Dis | 2018 | Monzio Compagnoni G, Kleiner G, Bordoni A, Fortunato F, Ronchi D, Salani S, Guida M, Corti C, Pichler I, Bergamini C, Fato R, Pellecchia MT, Vallelunga A, Del Sorbo F, Elia A, Reale C, Garavaglia B, Mora G, Albanese A, Cogiamanian F, Ardolino G, Bresolin N, Corti S, Comi GP, Quinzii CM, Di Fonzo A (2018) Mitochondrial dysfunction in fibroblasts of multiple system atrophy. Biochim Biophys Acta Mol Basis Dis 1864:3588-97. | OXPHOS ET ROUTINE | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Logan 2018 Mol Metab | 2018 | Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55. | LEAK OXPHOS | N S NS | Isolated mitochondria | Mouse | Nervous system |
| Matsumoto 2018 Circulation | 2018 | Matsumoto J, Takada S, Kinugawa S, Furihata T, Nambu H, Kakutani N, Tsuda M, Fukushima A, Yokota T, Tanaka S, Takahashi H, Watanabe M, Hatakeyama S, Matsumoto M, Nakayama KI, Otsuka Y, Sabe H, Tsutsui H, Anzai T (2018) Brain-derived neurotrophic factor improves limited exercise capacity in mice with heart failure. Circulation 138:2064-66. | LEAK ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Durand 2018 Blood Purif | 2018 | Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Platelet Blood cells |
| Merz 2018 Intensive Care Med Exp | 2018 | Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O (2018) Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp 6:43. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Pig | Kidney |
| Mahapatra 2018 Clin Sci (Lond) | 2018 | Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690 | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Human | Nervous system Blood cells |
| Goncalves 2018 Life Sci | 2018 | Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sci 193:234-41. | LEAK OXPHOS | N S NS ROX | Homogenate | Mouse | Liver |
| Niu 2018 Cancer Metab | 2018 | Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | HeLa |
| Marie 2018 Cell Death Dis | 2018 | Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis 9:287. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Endothelial;epithelial;mesothelial cell | |
| Santos Bertolini 2018 Thesis | 2018 | Santos Bertolini M (2018) Functional study of MICU1 and MICU2 proteins in calcium signaling of Trypanosoma cruzi. Master's Thesis 108. | LEAK OXPHOS ET | S | Permeabilized cells | Protists | |
| Piel 2018 Intensive Care Med Exp | 2018 | Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22. | LEAK | S ROX | Intact cells | Human | Platelet Blood cells |
| Holland 2018 Cell Death Dis | 2018 | Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Genital |
| Petiz 2018 Chem Biol Interact | 2018 | Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Liver |
| Zhang 2018 J Mol Cell Cardiol | 2018 | Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria | Mouse | Heart |
| Du 2018 Environ Sci Technol | 2018 | Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11. | LEAK ET | N S NS | Isolated mitochondria | Fishes | Liver |
| Vatner 2018 Aging Cell | 2018 | Vatner DE, Zhang J, Oydanich M, Guers J, Katsyuba E, Yan L, Sinclair D, Auwerx J, Vatner SF (2018) Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751. | LEAK OXPHOS | N S NS | Intact cells | Mouse | Fat |
| Smenes 2018 Interact Cardiovasc Thorac Surg | 2018 | Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
| Clarke 2018 Methods Mol Biol | 2018 | Clarke KJ, Porter RK (2018) The importance of calcium ions for determining mitochondrial glycerol-3-phosphate dehydrogenase activity when measuring uncoupling protein 1 (UCP1) function in mitochondria isolated from brown adipose tissue. Methods Mol Biol 1782:325-36. | LEAK | S Gp | Isolated mitochondria | Rat | Fat |
| Konopka 2018 Aging Cell | 2018 | Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880. | OXPHOS ET LEAK | F N NS S ROX | Permeabilized tissue | Human | Skeletal muscle |
| Sokolov 2018 Mitochondrion | 2018 | Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Molluscs | Lung;gill |
| Manoharan 2018 Thesis | 2018 | Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Fishes | Heart Liver |
| Paech 2018a Toxicology | 2018 | Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44. | LEAK OXPHOS ET | N S DQ CIV ROX | Permeabilized cells Isolated mitochondria | Human Mouse | Liver Other cell lines |
| Eimre 2018 Oxid Med Cell Longev | 2018 | Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313. | OXPHOS LEAK | N S CIV ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Burney 2018 Thesis | 2018 | Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50. | LEAK ROUTINE OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells Intact cells | Rat | Other cell lines |
| Sumbalova 2018 Nova Sciences | 2018 | Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and coenzyme Q10. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Briones-Herrera 2018 Food Chem Toxicol | 2018 | Briones-Herrera A, Avila-Rojas SH, Aparicio-Trejo OE, Cristóbal M, León-Contreras JC, Hernández-Pando R, Pinzón E, Pedraza-Chaverri J, Sánchez-Lozada LG, Tapia E (2018) Sulforaphane prevents maleic acid-induced nephropathy by modulating renal hemodynamics, mitochondrial bioenergetics and oxidative stress. Food Chem Toxicol 115:185-97. | LEAK OXPHOS | N NS S | Isolated mitochondria | Rat | Kidney |
| Mavroudis 2018 Eur J Cardiothorac Surg | 2018 | Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68. | LEAK ET OXPHOS | N S CIV NS ROX | Homogenate | Pig | Nervous system |
| Siira 2018 EMBO Rep | 2018 | Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart |
| Yang 2018 Cell Death Dis | 2018 | Yang F, Wu R, Jiang Z, Chen J, Nan J, Su S, Zhang N, Wang C, Zhao J, Ni C, Wang Y, Hu W, Zeng Z, Zhu K, Liu X, Hu X, Zhu W, Yu H, Huang J, Wang J (2018) Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation. Cell Death Dis 9:556. | N S CIV NS ROX | Intact cells | Mouse | ||
| Nielsen 2018 Neurosci Lett | 2018 | Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB (2018) Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue. Neurosci Lett 690:1-5. | LEAK OXPHOS ET | N NS ROX S | Homogenate | Rat | Nervous system |
| Scaini 2018 Eur Neuropsychopharmacol | 2018 | Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines Lymphocyte |
| De Villiers 2018 Adv Exp Med Biol | 2018 | de Villiers D, Potgieter M, Ambele MA, Adam L, Durandt C, Pepper MS (2018) The role of reactive oxygen species in adipogenic differentiation. Adv Exp Med Biol 1083:125-144. https://doi.org/10.1007/5584_2017_119 | S | Fat | |||
| Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | LEAK ROUTINE OXPHOS ET | F N S DQ NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Allard 2018 J Clin Endocrinol Metab | 2018 | Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84. | OXPHOS | F N S Gp CIV NS | Permeabilized tissue | Human | Skeletal muscle |
| Kauppila 2018 Thesis | 2018 | Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart Liver |
| Zimin 2018 Br J Anaesth | 2018 | Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32. | OXPHOS LEAK | N S ROX | Isolated mitochondria | Mouse | Nervous system |
| Karlsson 2018 J Neurotrauma | 2018 | Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T (2018) Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. J Neurotrauma 36:14-24. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
| Kim 2018 Free Radic Biol Med | 2018 | Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124:517-24. | OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
| Cecatto 2018 FEBS J | 2018 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca2+ homeostasis in the heart. FEBS J 285:1437-55. | LEAK OXPHOS ET | N S | Permeabilized cells Permeabilized tissue Isolated mitochondria | Rat | Heart Other cell lines |
| Christen 2018 Free Radic Biol Med | 2018 | Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Fishes | Heart |
| Kappler 2018 Thesis | 2018 | Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Skeletal muscle Liver Other cell lines |
| Kjeld 2018 PLoS One | 2018 | Kjeld T, Stride N, Gudiksen A, Hansen EG, Arendrup HC, Horstmann PF, Zerahn B, Jensen LT, Nordsborg N, Bejder J, Halling JF (2018) Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers. PLoS One 13:e0201401. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Bhaskaran 2018 EMBO Rep | 2018 | Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009. | LEAK OXPHOS | N S NS | Mouse | Fat | |
| Silaidos 2018 Biol Sex Differ | 2018 | Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Nervous system Blood cells |
| Lee 2018 Neurol Genet | 2018 | Lee RG, Sedghi M, Salari M, Shearwood AJ, Stentenbach M, Kariminejad A, Goullee H, Rackham O, Laing NG, Tajsharghi H, Filipovska A (2018) Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction. Neurol Genet 4:e276. | LEAK OXPHOS ET | N S CIV NS | Permeabilized cells | Human | Fibroblast |
| Jang 2018 Intensive Care Med Exp | 2018 | Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | Blood cells |
| Gorgey 2018 Eur J Appl Physiol | 2018 | Gorgey AS, Witt O, O'Brien L, Cardozo C, Chen Q, Lesnefsky EJ, Graham ZA (2018) Mitochondrial health and muscle plasticity after spinal cord injury. Eur J Appl Physiol 119:315-31. | OXPHOS LEAK | N S CIV NS | Permeabilized tissue | Human | Skeletal muscle |
| Tetri 2018 Front Physiol | 2018 | Tetri LH, Diffee GM, Barton GP, Braun RK, Yoder HE, Haraldsdottir K, Eldridge MW, Goss KN (2018) Sex-specific skeletal muscle fatigability and decreased mitochondrial oxidative capacity in adult rats exposed to postnatal hyperoxia. Front Physiol 9:326. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Skeletal muscle |
| Krug 2018 Thesis | 2018 | Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136. | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Intact cells Permeabilized cells | Rat | Other cell lines |
| Ounpuu 2018 Biochem Cell Biol | 2018 | Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print]. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Fink 2018 J Biol Chem | 2018 | Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41. https://doi.org/10.1074/jbc.RA118.005144 | OXPHOS | N S NS | Isolated mitochondria | Mouse | Skeletal muscle |
| Ravera 2018 Biol Cell | 2018 | Ravera S, Signorello MG, Bartolucci M, Ferrando S, Manni L, Caicci F, Calzia D, Panfoli I, Morelli A, Leoncini G (2018) Extramitochondrial energy production in platelets. Biol Cell 110:97-108. | N S | Permeabilized cells | Human | Blood cells Platelet | |
| Monaco 2018b Diabetologia | 2018 | Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR (2018) Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes. Diabetologia 61:1411-23. | OXPHOS | N S Gp NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Sims 2018 JCI Insight | 2018 | Sims CA, Guan Y, Mukherjee S, Singh K, Botolin P, Davila A Jr, Baur JA (2018) Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI Insight 3:120182. | OXPHOS | N S CIV ROX | Permeabilized cells Isolated mitochondria | Rat | Liver Kidney |
| Boutoual 2018 Sci Rep | 2018 | Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Wen 2018 PLOS Pathog | 2018 | Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLOS Pathog 14:e1007065. | OXPHOS | N S NS | Permeabilized tissue | Mouse | Heart Other cell lines |
| Valentine 2018 J Gerontol A Biol Sci Med Sci | 2018 | Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Mills 2018 Nature | 2018 | Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556:113-7. | ET | S | Isolated mitochondria | Rat | Liver |
| Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | LEAK OXPHOS ET | N S DQ CIV ROX NS | Isolated mitochondria | Mouse | Liver |
| Ryan 2018 JCI Insight | 2018 | Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235. | OXPHOS LEAK | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| McLaughlin 2018 Biochem Biophys Res Commun | 2018 | McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48. | N S F | Isolated mitochondria | Mouse | Heart | |
| Johnson 2018 J Mol Cell Cardiol | 2018 | Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K (2018) Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. J Mol Cell Cardiol 121:94-102. | OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Heart Skeletal muscle |
| Silva 2018 Nat Cell Biol | 2018 | Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH (2018) EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Nat Cell Biol 20:162-74. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Islet cell;pancreas;thymus | |
| Robb 2018 J Biol Chem | 2018 | Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293:9869-79. https://doi.org/10.1074/jbc.RA118.003647 | ET | N S ROX | Isolated mitochondria | Rat | Heart |
| Pardo 2018 FASEB J | 2018 | Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA (2018) Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue. FASEB J 33:2343-58. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Fat |
| Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | LEAK ET ROUTINE OXPHOS | N S | Homogenate Intact cells | Mouse | Fibroblast |
| Arena 2018 Mol Cell | 2018 | Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L (2018) Mitochondrial MDM2 regulates respiratory complex I activity independently of p53. Mol Cell 69:594-609. | OXPHOS | N S NS | Permeabilized cells | Human | Lung;gill Other cell lines |
| Gam 2018 Acta Diabetol | 2018 | Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Human | Genital |
| De Moura Alvorcem 2018 Mitochondrion | 2018 | De Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, Da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2018) Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum. Mitochondrion 47:141-50. | LEAK OXPHOS ET | N S NS | Isolated mitochondria Intact cells | Rat | Nervous system |
| Martins 2018 Oxid Med Cell Longev | 2018 | Martins IK, de Carvalho NR, Macedo GE, Rodrigues NR, Ziech CC, Vinadé L, Filho VMB, Menezes IA, Franco J, Posser T (2018) Anacardium microcarpum promotes neuroprotection dependently of AKT and ERK phosphorylation but does not prevent mitochondrial damage by 6-OHDA. Oxid Med Cell Longev 2018:2131895. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Chicken | Nervous system |
| Ramil 2018 Thesis | 2018 | Ramil LR, Gulbinas A, Cesna V (2018) “HIPEC” hyperthermic intraperitoneal chemotherapy. Evaluation of intraperitoneal free cancer cells. Master's Thesis. | OXPHOS LEAK | N S | Isolated mitochondria | Human | Endothelial;epithelial;mesothelial cell |
| Perks 2018 Cell Rep | 2018 | Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42. | LEAK OXPHOS ET | N Gp S | Isolated mitochondria | Mouse | Heart |
| Dogan 2018 Cell Metab | 2018 | Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77. | LEAK OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Skeletal muscle |
| Setz 2018 Hear Res | 2018 | Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Other cell lines |
| Chicco 2018 J Biol Chem | 2018 | Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Human | Skeletal muscle |
| Weber 2018 Int J Mol Sci | 2018 | Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129. | ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Intact cells Permeabilized cells | Human | Genital |
| Zhang 2018 Aging Dis | 2018 | Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue Homogenate | Rat | Nervous system |
