Search results

Page title matches

• Sies 2019 Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  ...homeostasis. Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series. 3:153-163. doi.org/10.1016/B978-0-12-813146-6.00013-8 |journal=Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  478 bytes (64 words) - 14:17, 4 February 2022
• Oxidative stress
  ...in pro-oxidants, by a depletion of antioxidant systems or both. Oxidative stress generates oxidative damage of proteins, lipids and DNA.
  401 bytes (54 words) - 13:26, 8 November 2016
• Neurobiol Stress
  ...=[https://www.journals.elsevier.com/neurobiology-of-stress Neurobiology of Stress]
  101 bytes (11 words) - 12:05, 13 January 2020
• MiP2013 Stress: Hypoxia
  {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Stress::Hypoxia]]
  458 bytes (63 words) - 14:48, 29 November 2016
• Salvi 2019 Neurobiol Stress
  ...mechanisms in air pollution-related neurobiological impairments. Neurobiol Stress 12:100205. |journal=Neurobiol Stress
  2 KB (219 words) - 12:31, 13 January 2020
• Sies 1985 Oxidative Stress
  ...985) Oxidative stress: introductory remarks. In: Sies H. editor. Oxidative stress. Academic Press; London 1–8.
  309 bytes (37 words) - 11:45, 22 March 2021
• Grasso 2020 Cell Stress
  ...Capelôa T, Van de Velde JA, Sonveaux P (2020) Mitochondria in cancer. Cell Stress 4:114-46. https://doi.org/10.15698/cst2020.06.221 |journal=Cell Stress
  2 KB (229 words) - 22:55, 12 October 2023
• O2k-Publications: RONS; Oxidative stress
  ...[[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Oxidative stress;RONS]] == O2k-Publications: Oxidative stress;RONS - Abstracts ==
  1 KB (191 words) - 16:11, 4 June 2017
• Jones 1985 Oxidative stress. Academic Press Inc (London) Ltd
  ...concentration in oxidative stress: hypoxic and hyperoxic models. Oxidative stress. Academic Press Inc (London) Ltd. 0-12-642760-7:151-195. ...&oi=fnd&pg=PA151&dq=Jones+PD+the+role+of+oxygen+concentration+in+oxidative+stress:+hypoxic+and+hyperoxic+models&ots=hlX8eUnw_F&sig=2CjSfBnj5051Jj1nEMamj4kGeS
  656 bytes (100 words) - 17:07, 3 February 2022
• 6th International Conference on Tumor Microenvironment and Cellular Stress 2019 Crete GR
  ...23-28. 6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets. |abstract=6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets, Chania, Crete, Gre
  1 KB (160 words) - 09:11, 8 October 2019

Page text matches

• Sies 2019 Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  ...homeostasis. Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series. 3:153-163. doi.org/10.1016/B978-0-12-813146-6.00013-8 |journal=Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  478 bytes (64 words) - 14:17, 4 February 2022
• Latent mitochondrial dysfunction
  ...in response to a particular (e.g. oxidative) stress, using a mitochondrial stress resistance test.
  794 bytes (104 words) - 16:32, 4 October 2011
• Jones 1985 Oxidative stress. Academic Press Inc (London) Ltd
  ...concentration in oxidative stress: hypoxic and hyperoxic models. Oxidative stress. Academic Press Inc (London) Ltd. 0-12-642760-7:151-195. ...&oi=fnd&pg=PA151&dq=Jones+PD+the+role+of+oxygen+concentration+in+oxidative+stress:+hypoxic+and+hyperoxic+models&ots=hlX8eUnw_F&sig=2CjSfBnj5051Jj1nEMamj4kGeS
  656 bytes (100 words) - 17:07, 3 February 2022
• Oliveira 2018 Front Physiol
  ...França TFA, Moreira DC, Hermes-Lima M (2018) Is "Preparation for Oxidative Stress" a Case of Physiological Conditioning Hormesis?. Front Physiol 9:945. |keywords=antioxidant, biochemical adaptation, estivation, hypoxia, oxidative stress, reactive oxygen species, redox
  595 bytes (76 words) - 13:20, 31 May 2019
• Kim 2024 J Exerc Rehabil
  ...m SH (2024) Exercise before pregnancy exerts protective effect on prenatal stress-induced impairment of memory, neurogenesis, and mitochondrial function in o ...e, exercise before pregnancy may have a protective effect against prenatal stress of the offspring.
  2 KB (317 words) - 16:34, 3 April 2024
• Breitenbach 2016 Biomolecules
  |title=Breitenbach M, Eckl P (Ed.) (2016) Oxidative stress in health and disease. Biomolecules p512. |abstract=Oxidative stress is now a well-researched area with thousands of new articles
  896 bytes (128 words) - 14:15, 26 March 2018
• Hijazi 2020 J Cell Sci
  ...signaling mediates an adaptive survival response to endoplasmic reticulum stress. J Cell Sci 133:jcs241539. ...oping therapeutic strategies to limit cell death in disorders linked to ER stress.
  2 KB (257 words) - 15:53, 7 May 2020
• Azzi 2022 Antioxidants (Basel)
  |title=Azzi A (2022) Oxidative stress: What is it? Can it be measured? Where is it located? Can it be good or bad ...sign. There is no officially approved therapy to prevent or cure oxidative stress or oxidative damage.
  2 KB (241 words) - 09:24, 1 May 2024
• Ma 2020 Oxid Med Cell Longev
  |title=Ma WX, Li CY, Tao R, Wang XP, Yan LJ (2020) Reductive stress-induced mitochondrial dysfunction and cardiomyopathy. Oxid Med Cell Longev ...vide novel insights into therapeutic approaches for ameliorating reductive stress-induced cardiomyopathy.
  2 KB (217 words) - 16:11, 3 February 2022
• Salvi 2019 Neurobiol Stress
  ...mechanisms in air pollution-related neurobiological impairments. Neurobiol Stress 12:100205. |journal=Neurobiol Stress
  2 KB (219 words) - 12:31, 13 January 2020
• Sharma 2023 Biosci Biotechnol Biochem
  ...023) Valine improves mitochondrial function and protects against oxidative stress. https://doi.org/10.1093/bbb/zbad169 ...tion thereby preventing mitochondrial/cellular damage induced by oxidative stress.
  2 KB (268 words) - 15:21, 20 December 2023
• Neurobiol Stress
  ...=[https://www.journals.elsevier.com/neurobiology-of-stress Neurobiology of Stress]
  101 bytes (11 words) - 12:05, 13 January 2020
• Pignatelli 2018 Kardiol Pol
  |title=Pignatelli P, Menichelli D, Pastori D, Violi F (2018) Oxidative stress and cardiovascular disease: new insights. Kardiol Pol 76:713-722. ...cardiovascular risk, and 3) therapeutic implications to modulate oxidative stress.
  1 KB (170 words) - 09:30, 14 December 2021
• Wang 2021 Oxid Med Cell Longev
  ...etal muscle, in order to clarify the effects of exercise-induced oxidative stress on the pathophysiological functions of skeletal muscle. |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (229 words) - 14:24, 4 February 2022
• Yan 2014 J Diabetes Res
  ...Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress. J Diabetes Res 2014:137919. https://doi.org/10.1155/2014/137919 ...llular oxidative stress. Therefore, reductive stress followed by oxidative stress comprises a major mechanism of hyperglycemia-induced metabolic syndrome.
  2 KB (256 words) - 06:12, 11 October 2023
• Rains 2011 Free Radic Biol Med
  |title=Rains JL, Jain SK (2011) Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med 50:567-75. ...view outlines various mechanisms that lead to the development of oxidative stress. Intervention and therapy that alter or disrupt these mechanisms may serve
  2 KB (227 words) - 09:30, 14 December 2021
• Oxidative stress
  ...in pro-oxidants, by a depletion of antioxidant systems or both. Oxidative stress generates oxidative damage of proteins, lipids and DNA.
  401 bytes (54 words) - 13:26, 8 November 2016
• Sies 1985 Oxidative Stress
  ...985) Oxidative stress: introductory remarks. In: Sies H. editor. Oxidative stress. Academic Press; London 1–8.
  309 bytes (37 words) - 11:45, 22 March 2021
• Xiao 2020 Antioxid Redox Signal
  |title=Xiao W, Loscalzo J (2020) Metabolic responses to reductive stress. Antioxid Redox Signal 32:1330-47. DOI: 10.1089/ars.2019.7803 ...loping strategies (e.g., antireductant approaches) to counteract reductive stress and its related adverse biological consequences also requires extensive fut
  2 KB (269 words) - 17:10, 3 February 2022
• Di 2011 EMBO J
  ...n K, Mironov A, Kotiadis VN, Gourlay CW, Jones N, Wilkinson CR (2011) H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphat ...PK signalling is controlled and providing an explanation for the oxidative stress-specific nature of the regulation of Sty1 by Ptc4.
  2 KB (274 words) - 16:28, 23 February 2015
• Robertson 2023 Abstract IOC160
  ...y how specific metabolic pathways are impacted in response to pathological stress and ultimately develop novel therapeutics designed to enhance mitochondrial
  2 KB (268 words) - 12:31, 6 June 2023
• Picard 2018 Psychosom Med
  |title=Picard M, McEwen BS (2018) Psychological stress and mitochondria: a systematic review. Psychosom Med 80:141-53. https://doi ...This article provides a systematic review of the effects of psychological stress on mitochondrial structure and function.
  2 KB (306 words) - 00:07, 13 September 2023
• Furlanetto 2014 Thesis University of Parana
  ...ited in both, 24h and 48h of stress. The cold stress induces the oxidative stress in embryogenic ''A. angustifolia'' cells, which result in up-regulation of ...ds=''Araucaria angustifolia'', Embryogenic cells, Plant mitochondria, Cold stress, Antioxidant enzymes
  3 KB (428 words) - 10:15, 9 November 2016
• Gak 2015 Biochim Biophys Acta
  ...vic SM, Dukic AR, Janjic MM, Stojkov-Mimic NJ, Kostic TS, Andric SA (2015) Stress triggers mitochondrial biogenesis to preserve steroidogenesis in Leydig cel ...anticipate our result to be a starting point for more investigations since stress is a constant factor in life and has become one of the most significant hea
  2 KB (338 words) - 10:38, 22 March 2016
• Li 2015 Oxid Med Cell Longev
  ...Bo H, Li J, Zhang Y and Ji LL (2015) Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome ...aken together, our data suggest that, during acute exercise, mitochondrial stress triggers the rat myocardial inflammatory response via NLRP3 inflammasome ac
  2 KB (279 words) - 09:16, 8 November 2016
• Hoek 2002 Gastroenterology
  ...epaired, impairs mitochondrial function, which further increases oxidative stress in the cell, leading to a vicious cycle of accumulating cell damage that is |injuries=Oxidative stress;RONS
  2 KB (305 words) - 11:14, 12 July 2023
• Moisoi 2018 MiP2018a
  ...of the initiating stress, mitochondria or the nucleus can take the lead in stress response initiation - ‘talks first’. In most situations the nucleus and
  2 KB (222 words) - 08:09, 13 September 2018
• Silber Ariel Mariano
  ...metabolism, amino acid metabolism, parasitology, redox stress, nutritional stress
  726 bytes (93 words) - 10:59, 15 February 2022
• UK Cambridge Martins LM
  |keyword=Stress, Parkinson's Disease, Apoptosis, Mitochondrial Signalling |keywords=Stress; parkinson's disease; apoptosis
  736 bytes (96 words) - 13:50, 15 September 2021
• Gumpp 2020 Mitochondrion
  ...Kolassa IT (2020) Mitochondrial bioenergetics in leukocytes and oxidative stress in blood serum of mild to moderately depressed women. Mitochondrion 58:14-2 ...ressed women. Alterations in mitochondrial energy production and oxidative stress did not linearly depend on the current severity of MDD. However, biological
  1 KB (196 words) - 15:47, 19 October 2021
• US CO Fort Collins Hamilton K
  ...aging, mitochondrial biogenesis, proteostasis, oxidative stress, energetic stress, comparative models, rapamycin, metformin, skeletal and cardiac muscle
  676 bytes (89 words) - 19:05, 20 November 2018
• Sies 1991 Am J Med
  |title=Sies H (1991) Oxidative stress: from basic research to clinical application. Am J Med 91:31-38. ...or of the pro-oxidants. A number of diseases are associated with oxidative stress, being the basis of antioxidant therapy. Current evidence in clinical resea
  972 bytes (133 words) - 11:48, 22 March 2021
• Duvigneau 2010 Shock
  ...usion does not induce oxidative stress but sustained endoplasmic reticulum stress in livers of rats subjected to traumatic/hemorrhagic shock. Shock 33:289-98 ...f the liver, independent of oxidative or nitrosylative stress. Although ER stress was not associated with depressed hepatocyte function, it may act as an ear
  3 KB (398 words) - 08:31, 16 June 2015
• Brodnanova 2021 Eur J Pharmacol
  ...imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. Eur J Pharmac ...ER stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. ER stress in SH-SY5Y cells was induced by either tunicamycin or thapsigargin in the p
  2 KB (333 words) - 16:01, 21 July 2021
• US CO Fort Collins Miller BF
  ...aging, mitochondrial biogenesis, proteostasis, oxidative stress, energetic stress, comparative models, rapamycin, metformin, skeletal and cardiac muscle
  720 bytes (92 words) - 02:44, 1 March 2023
• Erikstein 2010 J Cell Biochem
  ...kolaisen J, Kulawiec M, Singh KK, Gjertsen BT, Tronstad KJ (2010) Cellular stress induced by resazurin leads to autophagy and cell death via production of re ...phagy, and cell degradation. The ability of cells to tolerate this type of stress may be important in toxicity and chemoresistance.
  2 KB (323 words) - 18:21, 31 January 2020
• Ohsawa 2007 Nat Med
  ...gas markedly suppressed brain injury by buffering the effects of oxidative stress. Thus H₂ can be used as an effective antioxidant therapy; owing |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (251 words) - 18:19, 24 December 2021
• Saura-Esteller 2021 Int J Mol Sci
  ...Serret D, Gil J (2021) Activation of the integrated stress response and ER stress protect from fluorizoline-induced apoptosis in HEK293T and U2OS cell lines. ...t fluorizoline causes increased ER stress and activation of the integrated stress response, which in HEK293T and U2OS cells are protective against fluorizoli
  2 KB (316 words) - 12:00, 27 March 2023
• Kennedy 2017 Skelet Muscle
  ...Guiraud S (2017) Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle. Skelet Muscle 7:22. ...sess whether utrophin could attenuate mitochondria pathology and oxidative stress.
  2 KB (298 words) - 12:05, 15 January 2018
• Mohsin 2020 Arch Biochem Biophys
  ...on J, Hu Y, Hollander J, Lesnefsky EJ, Chen Q (2020) Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload. Arch Biochem Bi ...ndent calpains. The contribution of mitochondrial calpain activation in ER stress-mediated complex I damage was studied.
  3 KB (407 words) - 08:40, 7 October 2020
• Arya 2011 Diabetes Res Clin Pract
  |title=Arya AK, Pokharia D, Tripathi K (2011) Relationship between oxidative stress and apoptotic markers in lymphocytes of diabetic patients with chronic non ...sent study was undertaken to investigate the correlation between oxidative stress and apoptotic markers in lymphocytes of diabetic patients with chronic non
  2 KB (279 words) - 15:24, 1 December 2015
• Picard 2018 Biol Psychiatry
  ...el ES (2018) A mitochondrial health index sensitive to mood and caregiving stress. Biol Psychiatry 84:9-17. https://doi.org/10.1016/j.biopsych.2018.01.012 ...y, but the underlying cellular mechanisms are not well understood. Chronic stress may induce recalibrations in mitochondria leading to changes either in mito
  2 KB (340 words) - 00:09, 13 September 2023
• Crane 2013 PLoS One
  ...l LG, Steinberg GR, Tarnopolsky MA (2013) Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. PLoS One 8:e8 ...e results demonstrate that chronic skeletal muscle mitochondrial oxidative stress does not impact exercise induced mitochondrial biogenesis, but impairs the
  2 KB (250 words) - 16:07, 7 November 2016
• O2k-Publications: RONS; Oxidative stress
  ...[[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Oxidative stress;RONS]] == O2k-Publications: Oxidative stress;RONS - Abstracts ==
  1 KB (191 words) - 16:11, 4 June 2017
• Nakashima 2017 Free Radic Biol Med
  |title=Nakashima Y, Ohta S, Wolf AM (2017) Blue light-induced oxidative stress in live skin. Free Radic Biol Med 108:300-10. doi: 10.1016/j.freeradbiomed. ...reen, red, far red or infrared light did not. Blue light-induced oxidative stress was also detected in cultured human keratinocytes, but the per photon effic
  2 KB (240 words) - 17:56, 24 December 2021
• MiPschool Greenville 2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (130 words) - 15:56, 11 September 2014
• MiP2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (156 words) - 17:11, 8 June 2015
• Nold 2019 Psychoneuroendocrinology
  ...mitochondrial respiration to face allostatic load in a double-hit model of stress. Psychoneuroendocrinology 107:148-59. ...cortex and hippocampus, while only rats with the double-hit of adolescent stress and uCMS demonstrated increased mitochondrial activity in the hippocampus.
  3 KB (366 words) - 12:21, 9 July 2019
• Escribano-Lopez 2019 Cell Physiol Biochem
  ...tioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia.. Cell Physiol Biochem 52( ...f MitoQ on insulin secretion, oxidative stress, endoplasmic reticulum (ER) stress and nuclear factor kappa B (NFκB) signalling in a pancreatic β cell line
  3 KB (360 words) - 16:53, 3 June 2019
• MiPschool Cape Town 2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (133 words) - 15:59, 11 September 2014
• Liguori 2018 Clin Interv Aging
  ...D, Gargiulo G, Testa G, Cacciatore F, Bonaduce D, Abete P (2018) Oxidative stress, aging, and diseases. Clin Interv Aging 757–772. ...ng on a specific therapeutic target. Given the important role of oxidative stress in the pathogenesis of many clinical conditions and aging, antioxidant ther
  2 KB (290 words) - 09:29, 14 December 2021
• De Mello 2018 Life Sci
  ...in obesity, including related alterations, such as inflammation, oxidative stress, and apoptosis, and focusing on the whole organism, covering alterations in |injuries=Oxidative stress;RONS
  2 KB (267 words) - 03:31, 24 August 2021
• MiP2014 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (164 words) - 14:50, 29 November 2016
• Dutta 2013 Autophagy
  ...urgh C (2013) Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity. Autophagy 9:328-44. ...in could be utilized as a potential therapeutic strategy against oxidative stress-mediated damage in cardiomyocytes.
  3 KB (361 words) - 17:22, 23 February 2020
• Banday 2020 J Am Heart Assoc
  ...imal models. Here we show the nexus between high salt intake and oxidative stress causing renal tubular dopamine oxidation, which leads to mitochondrial and ...act on organelle function or inflammation. Resveratrol prevented oxidative stress, dopamine oxidation, organelle dysfunction, inflammation, and hypertension
  2 KB (335 words) - 09:02, 27 January 2020
• Timon-Gomez 2014 Abstract MiP2014
  ...ochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. ...itochondrial adaptation to different respiration rates, oxidative and salt stress.
  3 KB (377 words) - 16:42, 11 February 2015
• Weger 2020 Sci Rep
  ...nature in the prefrontal cortex for differential susceptibility to chronic stress. Sci Rep 10:18308. ...individuals with high behavioral susceptibility and resilience to chronic stress.
  2 KB (311 words) - 17:34, 4 November 2020
• Miranda Mendonca 2019 Neurochem Int
  ...F, da Silva Fragoso VM (2019) Highly aggressive behavior induced by social stress is associated to reduced cytochrome c oxidase activity in mice brain cortex ...cytochrome c oxidase. Therefore, aggressive behavior generated upon social stress associates to selective reduction in cytochrome c oxidase activity, with po
  2 KB (323 words) - 14:28, 17 April 2019
• Jelenik 2018 Mol Metab
  ...TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. ...mechanisms are unclear. We investigated how early-life exposure to chronic stress affects long-term insulin sensitivity.
  2 KB (312 words) - 13:26, 7 March 2020
• Wang 2017 Mol Cell
  ...uwerx J (2017) Systems phytohormone responses to mitochondrial proteotoxic stress. Mol Cell 68:540-51. ...dopsis through chemical or genetic interference. Mitochondrial proteotoxic stress activated a plant-specific UPR^mt and impaired plant growth and d
  2 KB (227 words) - 16:48, 8 January 2018
• De Punder 2022 Abstract Bioblast
  ...ens DS, Heim C, Entringer S (2022) Early life stress and perceived chronic stress are associated with increased immune cell mitochondrial DNA copy number in ...ges in PBMC mtDNAcn reflect an adaptation of mitochondria to psychological stress.
  3 KB (455 words) - 08:51, 28 July 2022
• Bullon 2015 Pharmacol Res
  .... In our experiments, LPS-treated fibroblasts provoked increased oxidative stress, mitochondrial dysfunction, reduced oxygen consumption and mitochondrial bi |injuries=Oxidative stress;RONS
  2 KB (208 words) - 15:27, 9 November 2016
• Vanasco 2008 Free Radic Res
  |title=Vanasco V, Cimolai MC, Evelson P, Alvarez S (2008) The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by al ...in the heart of septic rats. The treatment with LA prevented the oxidative stress and mitochondrial dysfunction observed in this model.
  1 KB (213 words) - 11:38, 18 April 2021
• Andziak 2006 Aging Cell
  ...at the pronounced longevity of naked mole-rats is independent of oxidative stress parameters. |injuries=Oxidative stress;RONS
  2 KB (304 words) - 14:15, 20 February 2015
• Gaur 2021 Int J Biometeorol
  ...review highlights the interconnection between high altitude and oxidative stress and the role of anti-oxidants to protect cells from oxidative damages and t
  2 KB (296 words) - 16:30, 3 February 2022
• Foo 2022 Trends Microbiol
  ...oo J, Bellot G, Pervaiz S, Alonso S (2022) Mitochondria-mediated oxidative stress during viral infection. Trends Microbiol 30:679-92. https://doi.org/10.1016 ...sms employed by viruses to interact with mitochondria and induce oxidative stress. Furthermore, we discuss how viruses benefit from increased ROS levels, how
  1 KB (180 words) - 12:52, 8 October 2023
• Sabogal-Guaqueta 2019 Biomed Pharmacother
  ...Oun A, Kortholt A, Boddeke E, Dolga A (2019) Linalool attenuates oxidative stress and mitochondrial dysfunction mediated by glutamate and NMDA toxicity. Biom ...therapeutic agent against neurodegenerative brain diseases where oxidative stress contributes to the pathology of the disease.
  3 KB (337 words) - 12:55, 4 November 2019
• Salvi 2016 Oxid Med Cell Longev
  ...conclusion, present study provides an interesting simulation of oxidative stress in hippocampal cells, which will serve as an excellent model to study mitoc |keywords=Tempol, Buthionine sulfoximine, Oxidative stress, Mitochondria, Mouse hippocampal HT22 cells
  2 KB (284 words) - 15:06, 9 November 2016
• Schneeberger 2015 Cell Rep
  ...orzano A, Gomis R, Claret M (2015) Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis. Cell Rep 12(3):361-70. ...s a fundamental mediator of enhanced GNG in the context of hypothalamic ER stress and establish α-MSH deficiency in proopiomelanocortin (POMC) neurons as a
  2 KB (248 words) - 17:25, 29 November 2016
• Singh 2015 Biochim Biophys Acta
  ...r J, Bonifacio A, Piquard F, Krähenbühl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesi ...he redox-dependant pathways linked to mitochondria, showing that reductive stress could trigger mitochondrial hormesis phenomenon.
  3 KB (355 words) - 20:26, 7 March 2020
• Fessler 2020 Nature
  ...schka H, Jae LT (2020) A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature 579:433-437. ...issing pathway that is triggered by mitochondrial stress. Mechanistically, stress-induced activation of OMA1 causes DELE1 to be cleaved into a short form tha
  2 KB (303 words) - 09:07, 16 August 2021
• Noh 2013 Cell Death Dis
  ...Ellisman MH, Weinreb RN, Perkins GA, Ju W-K (2013) Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic func ...potentials and strategies for protecting ONH astrocytes against oxidative stress-mediated mitochondrial dysfunction or alteration in glaucoma and other opti
  3 KB (396 words) - 22:37, 16 February 2021
• Friederich-Persson 2012 PLoS One
  ...uncoupling via the adenine nucleotide transporter and decreases oxidative stress in diabetic kidneys. PLoS One 7:e39635. ...regulation of UCP- 2 results in excessive uncoupling and reduced oxidative stress in the kidney via activation of ANT.
  3 KB (345 words) - 16:35, 7 November 2016
• Escames 2013 Horm Mol Biol Clin Investig
  ...duction at 5 months old. Five months later, however, oxidative/nitrosative stress markers increased in both male and female mice, thus eliminating the differ |keywords=Aging, Brain, Melatonin, Mitochondria, Oxidative stress
  2 KB (328 words) - 08:05, 21 February 2020
• Sureda 2005 Free Radic Res
  ...Fuentespina E, Cordova A, Tur JA, Pons A (2005) Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise. Fre ...is and lymphopenia inversely correlated with cellular markers of oxidative stress. Plasma malondialdehyde (MDA) directly correlated with neutrophil MPO activ
  2 KB (273 words) - 15:11, 9 November 2016
• Schneeberger 2013 Cell
  ...ath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87. ...nrecognized role for MFN2 argues for a crucial involvement in mediating ER stress-induced leptin resistance.
  2 KB (277 words) - 15:57, 27 March 2018
• Bullon 2016 Periodontol 2000
  ...therosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction? Periodontol 2000 64:139-53. ...se and diabetes lie at a fundamental intracellular level, namely oxidative stress and mitochondrial dysfunction, as a meeting background among such chronic d
  1 KB (196 words) - 09:27, 3 October 2016
• Snow 2015 PLoS One
  ...re CM, Bibby TS (2015) Quantifying integrated proteomic responses to iron stress in the globally important marine diazotroph ''Trichodesmium''. PLoS One 10. ...tic pathways as Trichodesmium reallocates the limiting resource under iron stress. ''Trichodesmium'' therefore displays a significant and integrated proteomi
  2 KB (297 words) - 15:31, 8 August 2023
• Feng 2020 Int J Biol Macromol
  ..., Shao M, Han J, Tang T, Zhang Y, Liu F (2020) TFAM, a potential oxidative stress biomarker used for monitoring environment pollutants in ''Musca domestica'' ...ts expression may serve as a useful biomarker for monitoring the oxidative stress induced by Cd, DOX or UV.
  2 KB (290 words) - 05:01, 21 November 2023
• Mastronicola 2011 IUBMB Life
  ...ucillo LP, Fiori PL, Sarti P (2011) Giardia intestinalis escapes oxidative stress by colonizing the small intestine: A molecular hypothesis. IUBMB Life 63:21 ...a greater capacity for redox buffering and a lower propensity to oxidative stress.
  2 KB (276 words) - 11:20, 21 January 2020
• Pich 2002 Free Radic Res
  ...latelet mitochondrial function of transfusional buffy coats from oxidative stress. Free Radic Res 36:429-36. ...ncing the protection of platelet mitochondrial function from the oxidative stress. The results support on one hand a possibility of protection of mitochondri
  2 KB (280 words) - 11:39, 18 April 2021
• Ost 2020 EMBO Rep
  ...es diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804. ...ts a novel diurnal action and key pathophysiological role of mitochondrial stress-induced GDF15 in the regulation of systemic energy metabolism.
  2 KB (326 words) - 12:54, 21 February 2023
• Morato 2016 Abstract IOC116
  ...nier C, Sandi C (2016) Impaired mitochondrial function mediates early life stress-induced depression. Mitochondr Physiol Network 21.11 ...findings might pave the way for the use of mitochondrial boosters to treat stress-related disorders such as depression.
  2 KB (248 words) - 19:58, 20 November 2016
• Iakovou 2022 Front Aging Neurosci
  ...Kourti M (2022) A comprehensive overview of the complex role of oxidative stress in aging, the contributing environmental stressors and emerging antioxidant ...ith the levels of prooxidant molecules. Therefore, it seems that oxidative stress plays a more complicated role than the one once believed and this role migh
  3 KB (365 words) - 00:55, 10 November 2023
• Cojocaru 2023 Antioxidants (Basel)
  ...cu R, Vlad CE, Blaj M, Foia LG (2023) Mitochondrial dysfunction, oxidative stress, and therapeutic strategies in diabetes, obesity, and cardiovascular diseas ...nally, we selected several representative biomarkers involved in oxidative stress and summarize the progress of therapeutic strategies.
  2 KB (230 words) - 15:15, 5 October 2023
• Friederich-Persson 2014 Adv Exp Med Biol
  ...ever, the Ang II effect was absent in p22(phox), suggesting that oxidative stress also modulates normal Ang II signaling. In conclusion, Ang II affects both |injuries=Oxidative stress;RONS
  2 KB (349 words) - 10:40, 9 November 2016
• Borras 2009 FEBS Lett
  ...Viña J (2009) Low ''in vivo'' brain glucose consumption and high oxidative stress in accelerated aging. FEBS Lett 583:2287-93. ...s been recently questioned. Our aim was to test whether there is oxidative stress in tissues critically involved in accelerated aging (senescence-accelerated
  1 KB (191 words) - 09:08, 14 October 2016
• Steiner 2017 Int J Biochem Cell Biol
  ...ng CH (2017) Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis. Int J Biochem Cell Biol 89:125-35. https://doi.org/10.1016/j ...e activity. Recent work has also emerged linking alcohol-induced oxidative stress with apoptosis providing new insight on the codependence of these interrela
  2 KB (291 words) - 05:40, 30 October 2023
• Yuan 2022 Oxid Med Cell Longev
  |title=Yuan Q, Zeng ZL, Yang S, Li A, Zu X, Liu J (2022) Mitochondrial stress in metabolic inflammation: modest benefits and full losses. Oxid Med Cell L ...hy in the context of mitochondrial dysfunction, and moderate mitochondrial stress can have a beneficial effect. This review summarises the research progress
  1 KB (194 words) - 11:04, 22 March 2023
• Moisoi 2019 MiP2019
  |title=[[Image:MoisoiN.jpg|left|90px|Nicoletta Moisoi]] The integrated stress response mediates mitochondria-nucleus communication in neurodegeneration. ...his mechanism contributes to intracellular and intercellular signalling of stress.
  2 KB (272 words) - 12:17, 27 August 2019
• Andric 2019b MiP2019
  ...mental prerequisites for survival. Mitochondria are a key component of the stress response in all cells. For steroid-hormones-producing cells, including also ...is stimulated by cAMP-PRKA, cGMP and β-adrenergic receptors. Accordingly, stress-triggered mitochondrial biogenesis represents an adaptive mechanism and doe
  3 KB (411 words) - 14:32, 26 September 2019
• Marini 2018 Proc Natl Acad Sci U S A
  ...A, Amelio I, Willis AE, Melino G (2018) TAp73 contributes to the oxidative stress response by regulating protein synthesis. Proc Natl Acad Sci U S A 115:6219 ...s study identifies a mechanism by which TAp73 contributes to the oxidative stress response and describes a completely unexpected role for TAp73 in regulating
  2 KB (351 words) - 15:59, 25 July 2018
• Moisoi 2009 Cell Death Differ
  ...oss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16:449-64. ...We therefore propose that this brain-specific transcriptional response to stress may be important in the advance of neurodegenerative diseases.
  2 KB (307 words) - 12:23, 3 May 2022
• Evinova 2022 Mol Cell Biochem
  ...arkova Z, Brodnanova M, Dibdiakova K, Racay P (2022) Endoplasmic reticulum stress induces mitochondrial dysfunction but not mitochondrial unfolded protein re ...E1α ribonuclease with STF-083010 did not protect the SH-SY5Y cells from ER stress-induced mitochondrial dysfunction. STF-083010 itself had significant impact
  2 KB (262 words) - 13:20, 5 December 2022
• Kowaltowski 2014 Abstract MiP2014
  |abstract=Mitochondria play a key role in adapting to stress. Cardiolipin, the main anionic phospholipid in mitochondrial (mt) membranes ...ce a cardiolipin synthase-null mutant strain is unable to adapt to thermal stress, this effect is cardiolipin-dependent. Interestingly, we found that the los
  2 KB (295 words) - 12:00, 16 June 2015
• Luevano-Martinez 2015 Biochim Biophys Acta
  ...a key determinant for mtDNA stability and segregation during mitochondrial stress. Biochim Biophys Acta 1847:587-98. ...ce a cardiolipin synthase-null mutant strain is unable to adapt to thermal stress as observed by a 60% increase of cells lacking mtDNA (ρ(0)). Interestingly
  2 KB (291 words) - 12:39, 2 August 2023
• Ottolenghi 2020 Minerva Anestesiol
  ...tini G, Brizzolari A, Samaja M, Chiumello D (2020) Hyperoxia and oxidative stress in anesthesia and critical care medicine. Minerva Anestesiol 86:64-75. doi ...of key words: ("hyperoxia" OR "FiO2" OR "oxygen therapy") AND ("oxidative stress" OR "ROS" OR "RNS" OR "lipid peroxidation") AND ("anesthesia" OR "surgery"
  2 KB (338 words) - 14:19, 4 February 2022
• Kassahun 2018 DNA Repair (Amst)
  ...repair deficiency but an indirect consequence of the compensatory cellular stress response that includes MAPK activation. |keywords=Apoptosis, Base excision repair, ''C. elegans'', NTH-1, Oxidative stress
  2 KB (320 words) - 12:05, 12 February 2018
• Banh 2015 Comp Biochem Physiol B Biochem Mol Biol
  ...y fish muscle mitochondria: Potential role in acute heat-induced oxidative stress. Comp Biochem Physiol B Biochem Mol Biol 191:99-107. ...a may be, at least in part, responsible for the ROS that lead to oxidative stress in fish tissues exposed to acute heat challenge.
  3 KB (375 words) - 17:46, 8 November 2016
• Alzaid 2015 Springer
  |title=Alzaid F, Patel VB, Preedy VR (2015) Biomarkers of oxidative stress in blood. In: Preedy V, Patel V (eds) General methods in biomarker research ...tools to evaluate oxidative imbalance or indicate the degree of oxidative stress.
  2 KB (353 words) - 11:58, 9 November 2023
• Duicu 2015 Biomed Res Int
  ...Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed |abstract=Oxidative stress is a pathomechanism causally linked to the progression of chronic cardiovas
  2 KB (243 words) - 17:53, 9 November 2017
• Grasso 2020 Cell Stress
  ...Capelôa T, Van de Velde JA, Sonveaux P (2020) Mitochondria in cancer. Cell Stress 4:114-46. https://doi.org/10.15698/cst2020.06.221 |journal=Cell Stress
  2 KB (229 words) - 22:55, 12 October 2023
• Mas-Bargues 2022 Antioxidants (Basel)
  ...th are indirect approaches, provide a reliable method to measure oxidative stress on a given sample. Recently, the Seahorse XF and the Oroboros O2k systems h |keywords=ROS, In vivo imaging, Oroboros, Oxidative stress, Redox state, Seahorse
  2 KB (279 words) - 16:07, 28 November 2022
• Dobrowolski 2021 Mol Genet Metab
  ...kley J, Blair HC (2021) Mesenchymal stem cell energy deficit and oxidative stress contribute to osteopenia in the Pah^enu2 classical PKU mouse. Mol ...mpetence involves an energy deficit. We posit energy support and oxidative stress reduction will enable Pah^enu2 MSC differentiation in the osteobl
  3 KB (365 words) - 15:00, 20 October 2021
• Korge 2015 Biochim Biophys Acta
  ...ss JN (2015) Increased reactive oxygen species production during reductive stress: the roles of mitochondrial glutathione and thioredoxin reductases. Biochim ...us factors. These findings may explain how ROS production during reductive stress overwhelms ROS scavenging capability, generating the net mitochondrial ROS
  2 KB (304 words) - 17:08, 3 February 2022
• Flockhart 2023 Redox Biol
  ...en FJ (2023) Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training. https://doi.org/10.10 ...s and support mitochondrial function and protein integrity under oxidative stress, in both Nrf2-dependent and independent manners. We here administered gluco
  2 KB (256 words) - 18:17, 22 September 2023
• Deutschman 2019 J Cell Sci
  ...dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses. J Cell Sci 132:jcs233783. ...rprisingly, we find that loss of NCAPD3 also sensitizes cells to oxidative stress. Together, these studies identify new, and possibly independent, roles for
  2 KB (302 words) - 15:44, 27 November 2019
• Paglialunga 2012 Diabetologia
  ...d oxidative stress; we also determined the impact of any reduced oxidative stress on muscle insulin sensitivity and mitochondrial function. ...mice, compared with mice on low-fat chow diet (LF) or HF alone. Oxidative stress was measured as protein carbonylation levels. Glucose tolerance tests, gluc
  3 KB (366 words) - 15:37, 15 June 2015
• Steffen 2023 J Exp Biol
  ...indicate possible trade-off of higher respiration. The high plasticity and stress tolerance of ''C. gigas'' mitochondria may contribute to the success of thi ..., High-resolution respirometry, Hypoxia tolerance, Mitochondria, Oxidative stress marker
  3 KB (379 words) - 18:14, 25 July 2023
• Hafen 2018 J Appl Physiol (1985)
  ...e CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol ( ...ed in human skeletal muscle in response to repeated exposures to mild heat stress.
  2 KB (313 words) - 13:04, 17 April 2019
• Flis 2018 Oxid Med Cell Longev
  ...2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mic ...Swim training also maintained mitochondrial function and lowered oxidative stress. These data suggest that modification of MAMs might play a crucial role in
  2 KB (306 words) - 16:32, 28 May 2018
• Johnson 2018 J Mol Cell Cardiol
  ...lar to TAZKD littermates. These findings indicate that resolving oxidative stress is not sufficient to suppress cardioskeletal myopathy associated with BTHS. |keywords=Barth syndrome, Cardiomyopathy, Mitochondria, Oxidative stress, Reactive oxygen species
  2 KB (335 words) - 02:29, 1 March 2020
• Temelie 2023 Int J Mol Sci
  ...integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. https://doi.org/10.33 ...chondria quality control, namely HtrA2 loss of function, and/or integrated stress response, namely CHOP loss of function, and genotoxicity to address the dis
  3 KB (341 words) - 15:58, 17 April 2023
• Breton-Romero 2014 Biochim Biophys Acta
  ...z-Molledo M, Brandes RP, Rial E, Enríquez JA, Lamas S (2014) Laminar shear stress regulates mitochondrial dynamics, bioenergetics responses and PRX3 activati ...l cells as active players, able to transduce the mechanical force of shear stress in the vascular endothelium into a biological response.
  2 KB (304 words) - 15:56, 9 November 2016
• Schafer 2001 Free Radic Biol Med
  ...ed with cell growth and development, signaling, and reductive or oxidative stress. |injuries=Oxidative stress;RONS
  2 KB (300 words) - 12:34, 31 May 2019
• Parajuli 2012 PLoS One
  ...ath after 48 hours. These results suggested that MitoQ decreased oxidative stress, tubular damage and cell death by improving mitochondrial function during c |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (318 words) - 09:41, 8 November 2016
• Shao 2016 Cell Res
  ...together, our results suggest a neuropeptide coordination of mitochondrial stress response in the nervous system.
  1 KB (202 words) - 02:50, 1 March 2020
• Dilberger 2019 Oxid Med Cell Longev
  ...2019) Mitochondrial oxidative stress impairs energy metabolism and reduces stress resistance and longevity of ''C. elegans''. Oxid Med Cell Longev 2019:68405 Nematodes were incubated with various concentrations of paraquat in a heat-stress resistance assay (37°C) using nucleic staining. The most effective concent
  3 KB (398 words) - 15:03, 5 December 2019
• Sandri 2016 Abstract Mito Xmas Meeting Innsbruck
  ...ive stress, and profound weakness. Mitochondrial dysfunction and oxidative stress directly affect acto-myosin interaction and force generation. Inhibition of
  2 KB (248 words) - 11:54, 14 December 2016
• Garnol 2014 Physiol Res
  ...f mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4. ...atocytes. Our data thus indicates that combination of HFD and peroxidative stress potentiates HFD damaging effect of mitochondria because both branches of th
  2 KB (272 words) - 14:18, 13 November 2017
• Bullon 2011 Free Radic Biol Med
  ...s in periodontal patients. Abnormal PBMC performance may promote oxidative stress and alter cytokine homeostasis. In conclusion, mitochondrial dysfunction co
  2 KB (267 words) - 15:27, 9 November 2016
• 6th International Conference on Tumor Microenvironment and Cellular Stress 2019 Crete GR
  ...23-28. 6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets. |abstract=6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets, Chania, Crete, Gre
  1 KB (160 words) - 09:11, 8 October 2019
• Boeck 2016 Mitochondrion
  ...d maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. ...ciation of alterations in immune cell mitochondrial functioning, oxidative stress and the pro-inflammatory phenotype observed in individuals with a history o
  3 KB (410 words) - 13:43, 2 March 2020
• Xu 2022 Sci Adv
  |title=Xu H, Ahn B, Van Remmen H (2022) Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating for ...vide a better understanding of the specific impacts of aging and oxidative stress on mechanisms related to muscle weakness that may point to future intervent
  2 KB (272 words) - 16:02, 2 November 2022
• Starovlah 2019a MiP2019
  ...rovlah-MitoEAGLE2019.JPG|left|90px|Isidora Starovlah]] Psychophysiological stress changes transcriptional profile of molecular markers of mitochondrial dynam ...the convergent pathways. Although psychophysical stress is the most common stress in human society, the markers of mitochondrial dynamics in myocardium were
  3 KB (398 words) - 14:50, 26 September 2019
• Bombaca 2022 BEC
  ...Menna-Barreto RFS (2022) Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism. Bioenerg Commun 2022.20. https://doi.org/10.26124/bec ...cal role in bioenergetics, mitochondria contribute decisively to oxidative stress due to electron leakage from the electron transfer system. Several function
  2 KB (303 words) - 10:44, 9 January 2023
• Cassereau 2020 Exp Neurol
  ...N, Verny C, Reynier P, Bonneau D, Lenaers G, Procaccio V (2020) Oxidative stress contributes differentially to the pathophysiology of Charcot-Marie-Tooth di ...sveratrol. Together, these results suggest that the reduction of oxidative stress may constitute a promising therapeutic strategy for CMT2K.
  2 KB (322 words) - 08:22, 21 February 2020
• Bombaca 2022 MitoFit
  ...Menna-Barreto RFS (2022) Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism. https://doi.org/10.26124/mitofit:2022-0016 — ''2022 .../Bombaca_2022_MitoFit.pdf Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism]<br/>
  3 KB (363 words) - 07:52, 8 January 2023
• Dosek 2007 Respir Physiol Neurobiol
  ...ek A, Ohno H, Acs Z, Taylor AW, Radak Z (2007) High altitude and oxidative stress. Respir Physiol Neurobiol 158:128-31. ...Therefore, special attention is necessary to curb the degree of oxidative stress.
  2 KB (214 words) - 16:28, 3 February 2022
• Temelie 2018 Oxid Med Cell Longev
  ...e same cells showed an impaired induction of bystander phenomena following stress insults. However, these cells responded adaptively when a challenge dose wa
  2 KB (328 words) - 13:55, 24 July 2018
• Pfeiffer 2017 Free Radic Biol Med
  ...Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol ...aining mitochondrial respiratory capacity. Its deficiency causes oxidative stress, which is associated with an increased glycolytic capacity and balanced by
  3 KB (365 words) - 15:42, 29 November 2017
• Ransy 2020 Int J Mol Sci
  ...A, Bouillaud F (2020) Use of H₂O₂ to cause oxidative stress, the catalase issue. Int J Mol Sci 21:9149. https://doi.org/10.3390/ijms212 ...sub>O₂) is a method commonly used to trigger cellular oxidative stress. However, the doses used (often hundreds of micromolar) are disproportional
  2 KB (252 words) - 10:13, 7 March 2024
• Sánchez-Iglesias 2009 J Neurochem
  ...nchez-Sellero I, Labandeira-García JL, Soto-Otero R (2009) Brain oxidative stress and selective behaviour of aluminium in specific areas of rat brain: potent ...luminium also enhanced the ability of 6-hydroxydopamine to cause oxidative stress and neurodegeneration in the dopaminergic system, which confirms its potent
  2 KB (297 words) - 16:53, 17 September 2018
• Sies 2017 Annu Rev Biochem
  |title=Sies H, Berndt C, Jones DP (2017) Oxidative Stress. Annu Rev Biochem 86:715-748. ...switches such as Nrf2/Keap1 or NF-κB/IκB is used for system-wide oxidative stress response. Nonradical species such as hydrogen peroxide (H2O2) or singlet mo
  2 KB (205 words) - 12:14, 22 March 2021
• Andric Silvana
  ::::** ''stress -/+ systemic or intratesticular blockade of different stress receptors (alpha1ADR; betaADR; GR)
  1 KB (147 words) - 08:11, 25 March 2021
• Welker 2013 Comp Biochem Physiol A Mol Integr Physiol
  ...ntioxidant system - coined over a decade ago as "preparation for oxidative stress" - controls the possible harmful effects of increased ROS formation during |keywords=Hypoxia, Anoxia, Antioxidants, Lipid peroxidation, Oxidative stress, Oxygen sensing
  2 KB (349 words) - 12:24, 31 May 2019
• Lin 2006 Nature
  |title=Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443:787-95. ...feature of neurodegeneration. Mutations in mitochondrial DNA and oxidative stress both contribute to ageing, which is the greatest risk factor for neurodegen
  1 KB (140 words) - 09:33, 12 April 2022
• Publications: AOX
  |?Stress |?Stress
  622 bytes (78 words) - 14:38, 7 March 2020
• Publications: AmR
  |?Stress |?Stress
  622 bytes (78 words) - 14:38, 7 March 2020
• Publications: search labels
  |?Stress |?Stress
  755 bytes (91 words) - 07:48, 27 March 2020
• Kucera 2014 Oxid Med Cell Longev
  ...rvinková Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes ''in vitro''. Oxid Med Cell Longev 20 ...tudy was designed to evaluate the effect of exogenous inducer of oxidative stress (tert-butyl hydroperoxide, tBHP) on nonfatty and steatotic hepatocytes isol
  2 KB (315 words) - 14:14, 9 November 2016
• Gvozdjakova 2020 Diagnostics (Basel)
  ...itochondrial respiration, endogenous coenzyme Q₁₀ and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176. ...disease progression. We tested whether CoQ₁₀ levels, oxidative stress and platelet mitochondrial bioenergetic function differ between groups of C
  3 KB (382 words) - 01:35, 4 November 2021
• Seo 2019 Exp Neurol
  ...y hippocampal mitochondrial function and neuroplasticity in post-traumatic stress disorder. Exp Neurol 322:113043. ...el, adenine nucleotide translocase, and cyclophilin-D. Exposure to extreme stress also decreased neuroplasticity by increasing apoptosis and decreasing the b
  3 KB (360 words) - 16:49, 9 April 2020
• Pantner 2021 Sci Rep
  ...from DJ-1 deficient (DJ-1 KO) hearts showed increased levels of glycative stress following I/R. Additionally, Complex I and Complex III glycation were found
  3 KB (387 words) - 13:49, 5 October 2021
• Harris 2019 Cell Metab
  ...to an accumulation of polyubiquitinated proteins, induction of proteotoxic stress, and cell death. These results indicate that depletion of GSH renders cance ...t shock factor 1; high-throughput screening; oxidative stress; proteotoxic stress; unfolded protein response
  2 KB (303 words) - 15:42, 31 May 2019
• Nolfi-Doneganab 2020 Redox Biol
  ...ROS), which contributes to both homeostatic signaling as well as oxidative stress during pathology. In this graphical review we provide an overview of oxidat |injuries=Oxidative stress;RONS
  1 KB (146 words) - 18:58, 12 August 2020
• Chen 2020 Chem Biol Interact
  ...n H (2020) TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chem Biol Interact 331:109249. ...e-1 (HO-1) and nuclear factor erythroid 2-related factor (Nrf2), which are stress-response proteins. ROS accumulation followed by the accumulation of hypoxia
  3 KB (379 words) - 20:46, 6 November 2020
• Polajnar 2014 Biochim Biophys Acta
  ...gates: correlation between cell death, aggregate number/size and oxidative stress. Biochim Biophys Acta 1843:2089-99. ...upon overexpression. Mutant- and oligomer-dependent increase in oxidative stress and cell death in cells bearing aggregates was shown. On the other hand, th
  2 KB (338 words) - 15:52, 27 July 2016
• Alandijany 2013 J Neurovirol
  ...uces mitochondrial dysfunction leading to ROS overgeneration and oxidative stress. |keywords=Oxidative stress, Pathogenesis, Rabies, Rabies virus, Reactive oxygen species
  3 KB (350 words) - 16:41, 16 October 2018
• Wang 2019 Free Radic Biol Med
  ...ests the protection mechanisms of Igf1r^+/- cells from oxidative stress through the activation of the mitochondrial respiratory chain and LKB1/AMPK ...ted cancer, IGF-1R, LKB1/AMPK pathways, Mitochondrial functions, Oxidative stress, Ulcerative colitis
  2 KB (341 words) - 12:04, 14 August 2019
• Perry 2002 Free Radic Biol Med
  ...ges, and we also consider other neurodegenerative diseases where oxidative stress has been implicated. Although much data remain to be collected, the broad s ...; Amyloid-β; Antioxidants; Homeostasis; Neurofibrillary tangles; Oxidative stress; Redox balance; Senile plaque; τ; Free radicals
  2 KB (224 words) - 11:30, 23 April 2015
• Heher 2022 Redox Biol
  ...nd hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target. https://doi.org/10.1016/j.redox.2022.10225 ...Thus, FSHD myogenesis is uniquely susceptible to hypoxia-induced oxidative stress as a consequence of metabolic mis-adaptation. Importantly, mitochondria-tar
  3 KB (416 words) - 14:58, 5 December 2022
• Quiles 2006 Plant Cell Environ
  ...ld of photosystem (PS) II, indicating the close synergistic effect of both stress fac- tors on PS II inhibition and the subsequent irreversible damage to the ...up-regulation of the PTOX and the thylakoidal NADH DH complex under these stress conditions supports a role for chlororespiration in the protection against
  2 KB (321 words) - 09:38, 11 September 2021
• Andreyev 2005 Biochemistry (Mosc)
  ...mission. It is suggested that mitochondria augment intracellular oxidative stress due primarily to failure of their ROS removal systems, whereas the role of
  2 KB (233 words) - 21:38, 11 April 2022
• Herst 2017 Front Endocrinol (Lausanne)
  ...es that modulate body metabolism. Under conditions of severe mitochondrial stress, mitochondria have been shown to traffic between cells, replacing mitochond |injuries=Oxidative stress;RONS, Hypoxia
  3 KB (410 words) - 03:21, 24 August 2021
• Boardman 2019 Can J Physiol Pharmacol
  ...adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress. Can J Physiol Pharmacol 98:139-46. ...ROS stress induced by high pressure perfusion, uric acid lowered oxidative stress and reduced infarct size. In contrast, uric acid blocked cardioprotection i
  2 KB (318 words) - 15:30, 7 May 2020
• Rodrigues 2018 Free Radic Biol Med
  ..., our results suggest a connection between sleep deprivation and oxidative stress, pointing to mitochondria as a possible target of this relationship. |keywords=Akt1, Antioxidant enzymes, Hsp83, Nrf2, Oxidative stress, Pale, Pp2a, Sleep disorders, p38β
  2 KB (277 words) - 16:51, 29 May 2018
• US TX Waco Koutakis P
  |keyword=Skeletal muscle, Oxidative stress, Peripheral Artery Disase
  342 bytes (44 words) - 16:31, 3 November 2022
• Peugnet 2022 Antioxidants (Basel)
  ...2) Mitochondrial-targeted therapies require mitophagy to prevent oxidative stress induced by SOD2 inactivation in hypertrophied cardiomyocytes. https://doi.o ...effect of MitoQ. Our data showed the importance of mitochondrial oxidative stress in the development of cardiomyocyte hypertrophy. We observed that targeting
  3 KB (351 words) - 16:44, 30 November 2022
• Vega 2006 Enzyme Microb Technol
  ...s and respiration in ''Chlamydomonas reinhardtii''. Induction of oxidative stress. Enzyme Microb Technol 40:163-7. ...NaCl concentration in the culture medium. These data indicate that abiotic stress induces in ''C. reinhardtii'' an increase of intracellular peroxide, which
  2 KB (292 words) - 15:34, 8 August 2023
• Boada 2004 Free Radical Biol Med
  ...rgy limitation in the mink lung epithelial cell line Mv1Lu. This metabolic stress reduced the ATP available in transfected cells by 20%, which downregulated |keywords=Metabolic stress, 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase, Fructose 2,6-bisphos
  2 KB (213 words) - 17:12, 19 February 2018
• Schottlender 2021 Biomolecules
  ...perbaric oxygen treatment: effects on mitochondrial function and oxidative stress. Biomolecules 11:1827. https://doi.org/10.3390/biom11121827 ...rrent views on the effects of HBOT on mitochondrial function and oxidative stress, the interplay between them and the implications for several diseases.
  2 KB (245 words) - 00:11, 4 November 2023
• Tretter 2005 Philos Trans R Soc Lond B Biol Sci
  ...05) Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philos Trans R Soc Lond B Biol Sci 360:2335-45. ...enzyme could be critical in the metabolic deficiency induced by oxidative stress. Aconitase in the Krebs cycle is more vulnerable than alpha-KGDH to ROS but
  2 KB (231 words) - 13:47, 27 March 2018
• Airik 2023 Antioxidants (Basel)
  ...sis. Our findings indicate that therapeutic modulation of kidney oxidative stress may be a promising avenue to mitigate FAN1/KIN kidney pathophysiology and d ...N1, Chronic kidney disease, Karyomegalic interstitial nephritis, Oxidative stress
  3 KB (393 words) - 16:18, 16 May 2023
• Aral 2018 MiP2018
  ...e literature to clarify the effects of LETM1 loss in relation to oxidative stress and melatonin on mitochondrial function. |injuries=Oxidative stress;RONS
  3 KB (399 words) - 09:15, 20 August 2018
• Dannheisig 2019 Cells
  ...mitochondria and that PPAN knockdown triggers a p53-independent nucleolar stress response culminating in mitochondrial apoptosis. Here, we demonstrate a nov ...rkin, Wnt target, Apoptosis, Autophagy, Mitochondria, Mitophagy, Nucleolar stress, Nucleolus, Ribosome
  2 KB (289 words) - 13:22, 27 August 2019
• UK London Carling D
  Cellular Stress Group,
  357 bytes (49 words) - 13:57, 15 September 2021
• Verschoor 2013 Cancer Metab
  ...gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers. Cancer Metab 1:17. ...ology, and network representations were visualized in Cytoscape. Oxidative stress regulation was examined in ovarian cancer cells by measuring protein expres
  3 KB (387 words) - 15:16, 9 November 2016
• Moisoi 2017 MiP2017
  ...ytoplasmic stress), DNA damage and repair signalling, as well as oxydative stress responses. The data demonstrates that PINK1 modulates these signalling path
  2 KB (288 words) - 13:22, 23 October 2017
• Agudelo 2014 Cell
  ...muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell 159:33-45. ...ic PGC-1α1 transgenic mice resistant to depression induced by chronic mild stress or direct kynurenine administration. This study opens therapeutic avenues f
  2 KB (276 words) - 00:48, 13 December 2021
• Schoenfeld 2016 J Cereb Blood Flow Metab
  ...tion of b-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab 37:848-54. ...ive stress in cerebral tissue. This question is important, since oxidative stress is the cause of neurodegeneration in numerous neurodegenerative or inflamma
  2 KB (298 words) - 16:23, 9 May 2017
• Van den Berg 2017 Am J Respir Crit Care Med
  ...ess are unknown, but might include mitochondrial dysfunction and oxidative stress. ...itochondrial function and structure, and by increased markers of oxidative stress.
  3 KB (379 words) - 15:37, 21 August 2019
• TR Istanbul Dogan SA
  |keyword=mitochondrial myopathy, reactive oxygen species, mitochondrial stress signaling
  407 bytes (53 words) - 11:49, 1 February 2021
• Battaglia 2020 Cell Death Dis
  ...f neuronal activity, which are linked to increased intracellular oxidative stress, and to the activation of the NF-kB/c-Abl/DRP1 axis.
  2 KB (278 words) - 17:12, 2 December 2020
• Thomas 2011 Mitochondrion
  ...s and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18. ...entration-dependent reduction of methylpyridinium (MPP+)-induced oxidative stress and increases in lowered ATP levels and viability. Mice treated with weekly
  2 KB (214 words) - 15:36, 9 November 2016
• Rodriguez 2022 Abstract Bioblast
  ...N (2022) Mitonuclear interactions impact responses to metabolic and redox stress at different life stages in ''Drosophila melanogaster''. '''Bioblast 2022: ...tonuclear mismatches can lead to diverging responses to mild physiological stress, undermining fitness in some cases, but surprisingly improving outcomes in
  2 KB (295 words) - 08:49, 28 July 2022
• Alcocer-Gomez 2016 Biochim Biophys Acta
  ...m from caloric restricted mice improved the response to moderate oxidative stress and mitochondrial metabolism in FM fibroblasts. These results suggest that ...MPK, Caloric restriction, Fibromyalgia, Metformin, Mitochondria, Oxidative stress
  2 KB (325 words) - 08:14, 21 February 2020
• Hoepken 2007 Neurobiol Dis
  ...zed lymphoblasts from three patients homozygous for G309D-PINK1. Oxidative stress was evident from increases in lipid peroxidation and in antioxidant defense |keywords=Malondialdehyde, MnSOD, Glutathione, Mitochondria, Oxidative stress, PINK1, PARK6;, Fibroblasts
  2 KB (327 words) - 17:04, 19 February 2018
• Masci 2008 Biochim Biophys Acta
  ...ex IV. It is suggested that the peculiar response of AT mitochondria to NO stress may be relevant to the mitochondrial metabolism of AT patients. |keywords=Nitrosative stress, Bioenergetics, Cytochrome c oxidase, Genetic disease, Reaction mechanism,
  2 KB (292 words) - 11:20, 21 January 2020
• Starovlah 2019b MiP2019
  ..., calcium homeostasis, steroid biosynthesis, but also the key component of stress response. However, the molecular adaptation of spermatozoa from stressed ma ...pproach, epididymal spermatozoa from undisturbed rats were stimulated with stress hormones adrenaline and cortisol.
  3 KB (394 words) - 14:58, 26 September 2019
• Stefanatos 2012 Cell Cycle
  ...A, Ayala V, Jacobs HT, Pamplona R, Sanz A (2012) dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. Cell Cy ...this mutation. Our results reveal an important role of dj-1β in oxidative stress handling, insulin-like signaling and development in Drosophila melanogaster
  2 KB (278 words) - 15:27, 26 March 2018
• Dogan 2014 Cell Metab
  ...R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell ...respiratory chain deficiency, questioning the current view on the role of stress responses in mitochondrial diseases.
  2 KB (285 words) - 15:05, 3 February 2021
• Hernandez-Mijares 2011 Free Radic Biol Med
  ...tochondrial function. We also propose that one of the targets of oxidative stress responsible for diabetes is mitochondrial complex I. |injuries=Oxidative stress;RONS
  2 KB (289 words) - 16:10, 9 November 2016
• Ma 2015 Int J Biol Sci
  ..., Li PA, Bang JJ (2015) Silver nanoparticle exposure induced mitochondrial stress, caspase-3 activation and cell death: amelioration by sodium selenite. Int ...d activation of caspase-3. It is concluded that AgNP induces mitochondrial stress and treatment with selenite is capable of preventing the adverse effects of
  2 KB (287 words) - 14:19, 9 November 2016
• Bertero 2018 Nat Rev Cardiol
  ...ng conditions. Treatments targeting substrate utilization and/or oxidative stress in mitochondria are currently being tested in patients with heart failure a
  2 KB (264 words) - 21:53, 19 October 2023
• Brahma 2014 J Lipid Res
  ...R, Haemmerle G (2014) Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis. J Lipid Res 55:2229-41. ...ether, our results show that FGF21 expression is activated upon cardiac ER stress linked to defective lipolysis and that a persistent increase in circulating
  2 KB (342 words) - 17:01, 9 November 2017
• Volodina M
  |topics=mitochondria, oxidative stress, pregnancy disorders, fertility
  452 bytes (50 words) - 16:38, 13 June 2017
• Martins L
  Cellular Stress Group,
  377 bytes (48 words) - 12:26, 14 February 2018
• Safiedeen 2016 Antioxid Redox Signal
  ...ss talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox ...ochondrial reactive oxygen species (ROS). Pharmacological inhibition of ER stress and silencing of neutral sphingomyelinase with siRNA abrogated all MP-media
  3 KB (375 words) - 12:48, 4 June 2018
• Mancinelli 2016 Front Physiol
  ...e Himalayas were compared. Satellite cells were investigated for oxidative stress (oxidant production, antioxidant enzyme activity, and lipid damage), mitoch ...esent study supports the phenomenon of hypobaric-hypoxia-induced oxidative stress and its role in the impairment of the regenerative capacity of satellite ce
  2 KB (289 words) - 09:47, 29 September 2016
• Ugarteburu 2020 J Clin Med
  ...used by HACE1 mutations: alterations in autophagy, mitophagy and oxidative stress response. J Clin Med 9:E913. ...r abnormalities. However, an important increase in mitochondrial oxidative stress markers and a strong reduction in the mitophagic flux were observed, sugges
  3 KB (357 words) - 15:50, 6 April 2020
• Shinmura 2013 Oxid Med Cell Longev
  |title=Shinmura K (2013) Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins. Oxid M ...irtuins play an essential role in the reduction of mitochondrial oxidative stress during caloric restriction. We speculate that cardiac sirtuins attenuate th
  2 KB (271 words) - 23:03, 23 April 2023
• Zelenka 2016 Oxid Med Cell Longev
  ...ce these pathologies are associated with aging, inflammation and oxidative stress, we investigated whether hyperbilirubinemia interferes with ROS homeostasis ...ated serum bilirubin is generally associated with attenuation of oxidative stress, and with better anthropometric parameters, decreased inflammatory status,
  2 KB (306 words) - 10:45, 17 August 2022
• Yu 2017 Free Radic Biol Med
  ...n end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lys ...e and myocardial dysfunction in HFD mice. Attenuation of cardiac oxidative stress and maintenance of healthy mitochondria population ensuring adequate energy
  3 KB (430 words) - 17:54, 23 February 2020
• Cervinkova 2007 Altern Lab Anim
  ...ial function in isolated rat hepatocytes and mitochondria during oxidative stress. Altern Lab Anim 35:353-61. ...measurements, also confirmed the dramatic impact of tBHP-induced oxidative stress on mitochondria. Swelling was observed in isolated mitochondria exposed to
  3 KB (374 words) - 10:17, 24 March 2015
• Jardim-Messeder 2015 New Phytol
  ...source of reactive oxygen species in plants and regulates development and stress responses. New Phytol 208:776-89. ...t source of ROS in plant mitochondria and regulating plant development and stress responses.
  3 KB (370 words) - 17:19, 16 February 2021
• Reactive nitrogen species
  ...NO• plays an important role in cell signaling and in oxidative-nitrosative stress.
  334 bytes (42 words) - 15:34, 23 October 2014
• Flis 2019 Int J Mol Sci
  ...rome c oxidase and malate dehydrogenase activities, and elevates oxidative stress markers in skeletal muscle. Swim training slows the reduction in muscle str ...s=ALS, Bioenergetics, Exercise, Mitochondria, Neurodegeneration, Oxidative stress
  2 KB (350 words) - 10:20, 8 August 2019
• Vaka 2019 Am J Physiol Regul Integr Comp Physiol
  ...depletion indicate an important role of NK cells in mediating mt oxidative stress in the pathology of PE. |keywords=Natural Killer cells, Placental ischemia, Mitochondria, Oxidative stress
  3 KB (387 words) - 14:49, 15 May 2019
• Xiao 2018 Antioxid Redox Signal
  ...H) and NADP(H) pools. The concept of redox stress (oxidative and reductive stress) reflected by changes in NAD(H)/NADP(H) has increasingly gained attention. ...s to ensure their normal functions and simultaneously avoid inducing redox stress. In addition, it is essential to understand how NAD(H)- and NADP(H)-utilizi
  3 KB (389 words) - 22:55, 3 November 2023
• Maarman 2016 J Appl Physiol (1985)
  ...in protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C₂C₁₂ myotubes. J A ...with control, uric acid increased triglyceride content by ~237%, oxidative stress by 32%, and antioxidant capacity by 135%. Uric acid also reduced endogenous
  3 KB (363 words) - 14:36, 23 February 2021
• Rojas-Morales 2019 Free Radic Biol Med
  ...ez-Lozada LG, Pedraza-Chaverri J, Tapia E (2019) Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusi ...int out to fasting as a robust nutritional intervention to limit oxidative stress and mitochondrial dysfunction in early acute kidney injury and also to prom
  2 KB (255 words) - 11:28, 16 August 2019
• Wang 2018 J Nutr Biochem
  ...llow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high f ...hese diet treatment durations, muscle mitochondrial activity and oxidative stress remained unchanged and do not seem to have a major role in the observed imp
  3 KB (414 words) - 14:13, 8 August 2019
• MiP2013 Diseases: Diabetes;Obesity
  |?Stress |?Stress
  879 bytes (116 words) - 14:49, 29 November 2016
• Marie 2018 Cell Death Dis
  ...T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Ce ...ctor for age-related macular degeneration (AMD). We investigated oxidative stress markers and mitochondrial changes in A2E-loaded retinal pigment epithelium
  2 KB (360 words) - 16:12, 16 February 2022
• Serviddio 2004 Hepatology
  ...secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress. Hepatology 39:711-20.. ...1) to identify the mechanisms involved in glutathione depletion, oxidative stress, and mitochondrial impairment during biliary cirrhosis induced by chronic c
  2 KB (335 words) - 16:09, 17 October 2016
• Nabben 2011 Biochim Biophys Acta
  ...g-but did not observe any protective effect of UCP3. We examined oxidative stress by quantifying 4-hydroxynonenal protein adducts and protein carbonyls in th |keywords=UCP3, oxidative stress, ROS, skeletal muscle mitochondria, oxidative capacity, fatty acids
  2 KB (308 words) - 16:24, 27 March 2018
• Pruett 2022 Biol Sex Differ
  ...M, Romero DG, Yanes Cardozo LL (2022) Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition. ...reduces adiposity via improvement in mitochondrial function and oxidative stress in WAT in PCOS model.
  3 KB (495 words) - 13:28, 29 August 2022
• Schulz 2007 Cell Metab
  ...' life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab 6:280-93. ...e oxygen species (ROS), induces catalase activity, and increases oxidative stress resistance and survival rates, altogether providing direct evidence for a h
  2 KB (240 words) - 10:11, 9 November 2016
• Christiansen 2015 Am J Physiol Heart Circ Physiol
  ...tochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308: ...ation (OXPHOS) capacity was impaired with enhanced mitochondrial oxidative stress in HCM. Cardiac and skeletal muscles were obtained from nine domestic cats
  3 KB (373 words) - 17:34, 25 February 2020
• Coppin 2020 Cell Death Dis
  ...rchet N, Pigny P (2020) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death Dis 11:360. ...ria, preserves the integrity of mitochondrial network and modulates the ER stress response.
  3 KB (402 words) - 16:53, 18 May 2020
• Alves 2017 Free Radic Biol Med
  ...enium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol ...uggest that RuC has antitumor activity through the modulation of oxidative stress and impairment of oxidative phosphorylation, thus promoting Walker-256 cell
  2 KB (352 words) - 14:12, 12 October 2017
• Lopez-Grueso 2014 Antioxid Redox Signal
  ...Early, but not late onset estrogen replacement therapy prevents oxidative stress and metabolic alterations caused by ovariectomy. Antioxid Redox Signal 20:2 ...e usefulness of estrogen replacement therapy (ERT) in preventing oxidative stress associated with menopause is controversial. We aimed to study if there is a
  2 KB (315 words) - 14:59, 12 October 2016
• Zhou 2020 Biomed Pharmacother
  ...These results demonstrate that the improvement of mitochondrial oxidative stress and mitochondrial dysfunction is implicated in the mechanism of DNLA-mediat ...ds=Acute liver injury, Carbon tetrachloride, Nrf2, Mitochondria, Oxidative stress
  3 KB (399 words) - 04:45, 21 November 2023
• Bottje 2019 Poult Sci
  ...ochondrial ROS occurs in broilers in pulmonary hypertension syndrome, heat stress, and in the phenotypic expression of feed efficiency. Low levels of mitocho
  2 KB (273 words) - 10:43, 6 November 2023
• Moon 2012 J Korean Med Sci
  ...unction in the liver, and this is associated with an increase in oxidative stress and inflammation. |keywords=Bisphenol A, Liver, Oxidative Stress, Inflammation, HepG2 cells
  2 KB (297 words) - 16:06, 25 November 2015
• MiP2013 Diseases: Neurodegenerative
  |?Stress |?Stress
  1 KB (170 words) - 14:53, 29 November 2016
• Dirmeier 2002 J Biol Chem
  ...on RO (2002) Exposure of yeast cells to anoxia induces transient oxidative stress. Implications for the induction of hypoxic genes. J Biol Chem 277:34773-84. ...indicate that yeast cells exposed to anoxia experience transient oxidative stress and raise the possibility that this initiates the induction of hypoxic gene
  3 KB (374 words) - 17:51, 13 April 2022
• Guachalla 2009 Aging (Albany NY)
  ...f ''Sod2'' resulted in reduced SOD2 protein levels and increased oxidative stress in aging telomere dysfunctional mice, but this did not lead to an increase |keywords=Oxidative stress, Superoxide, Telomere shortening, Aging, DNA damage, SOD2, Free radicals, S
  2 KB (332 words) - 09:00, 8 March 2020
• Muellebner 2015 Biomolecules
  ...5) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701. ...m against hemin-induced toxicity. BR at slightly elevated levels induces a stress response at the ER, resulting in a decreased proliferative and metabolic ac
  3 KB (391 words) - 12:12, 8 November 2016
• Quispe 2018 Redox Biol
  ...em AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent ant ...al cell line (HT22) exposed to tert-BuOOH (''in vitro'' model of oxidative stress), as well as to elucidate potential mechanisms underlying this protection.
  3 KB (353 words) - 09:06, 5 May 2020
• Pokkunuri 2020 Am J Physiol Renal Physiol
  ...hat PDI inhibition diminishes Nrf2 nuclear translocation causing oxidative stress that further triggers mitochondrial dysfunction and renal cell apoptosis. T |keywords=Apoptosis, Keap1/Nrf2, Mitochondria, Oxidative Stress, PDI
  2 KB (325 words) - 18:16, 6 November 2020
• Kar 2021 Toxicol Rep
  ...s and toxicity at higher doses are attributed to mild and strong oxidative stress, respectively. Overall, the study provides a comprehensive understanding of |injuries=Oxidative stress;RONS
  2 KB (267 words) - 13:05, 12 July 2023
• Du 2017 Evolution
  ...f previous suggestions that mitochondrial dysfunction can induce oxidative stress and thus contribute to hybrid breakdown. |keywords=Energy metabolism, Oxidative stress, Post-zygotic isolation, Speciation, Temperature, Thermal sensitivity, Ampl
  2 KB (315 words) - 13:01, 7 March 2020
• Pham 2020 Eur J Appl Physiol
  ...We investigated the effect of MitoQ and CoQ10 supplementation on oxidative stress and skeletal muscle mitochondrial ROS levels and function in healthy middle ...ass and antioxidant defences were measured in muscle samples and oxidative stress markers in urine and blood samples.
  3 KB (370 words) - 14:18, 17 January 2023
• Lagendijk 1996 J Lipid Res
  ...ed forms of coenzyme Q10 in human plasma as a possible marker of oxidative stress. J Lipid Res 37:67-75. ...10 ratio may be a sensitive and practical way to measure in vivo oxidative stress. Furthermore, this indicator is independent from plasma total cholesterol c
  2 KB (297 words) - 13:47, 24 August 2021
• Morales-Alamo 2014 Free Radic Biol Med
  ...y when performed in severe acute hypoxia. However, with training oxidative stress is reduced. Paradoxically, total plasma antioxidant capacity increases duri |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (267 words) - 14:21, 4 February 2022
• Andziak 2006a Aging Cell
  ...findings strongly suggest that mechanisms other than attenuated oxidative stress explain the impressive longevity of this species. |injuries=Oxidative stress;RONS
  2 KB (311 words) - 14:56, 28 March 2018
• Nordquist 2015 J Am Soc Nephrol
  ...sport efficiency. These improvements could be related to reduced oxidative stress and account for the reduced proteinuria and tubulointerstitial damage. Thus |injuries=Oxidative stress;RONS
  2 KB (312 words) - 16:25, 27 March 2018
• Cahova 2016 Am J Physiol Gastrointest Liver Physiol
  ...Kazdova L (2016) Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. Am ...ormin (150 mg·kg body wt(-1)·day(-1)). Metformin treatment prevented acute stress-induced necroinflammatory reaction, reduced alanine aminotransferase and as
  3 KB (391 words) - 08:15, 21 February 2020
• Mazzoli 2019 Nutrients
  ...agnuolo MS, Cancelliere R, Gatto C, Iossa S (2019) Early hepatic oxidative stress and mitochondrial changes following western diet in middle aged rats. Nutri ...pid peroxidation and Nitro-Tyrosine content, taken as markers of oxidative stress, as well as NADPH oxidase activity, were significantly higher in HFF rats,
  3 KB (382 words) - 17:04, 11 November 2019
• Ren 2017 Front Pharmacol
  ...Zhang Y (2017) Silencing of NAC1 expression induces cancer cells oxidative stress in hypoxia and potentiates the therapeutic activity of elesclomol. Front Ph ...Our findings reveal a novel mechanism by which NAC1 facilitates oxidative stress resistance during cancer progression, and chemo-resistance in cancer therap
  2 KB (311 words) - 12:50, 26 January 2018
• Hamilton 2016 Am J Physiol Heart Circ Physiol
  ...oarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. ...d with impaired mitochondrial respiratory function and increased oxidative stress compared with either l-NAME or AngII alone, resulting in nonischemic HF.
  3 KB (410 words) - 17:18, 7 November 2016
• NL Amsterdam Nollet E
  ...=Bio-energetics, heart failure, cardiac muscle, skeletal muscle, oxidative stress
  421 bytes (52 words) - 23:06, 4 July 2022
• Langley 2019 Biochim Biophys Acta Mol Basis Dis
  ...High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Ac ...s in metabolic regulators, decreased mitochondrial function, and oxidative stress contribute to a loss of myelinating cells. These studies identify HFD consu
  3 KB (372 words) - 11:20, 3 March 2020
• Pichova A
  ...and newly with mouse model – tissue or rather lysate – within the study of stress and drug, diseases influence on mitochondria in intestinal system and margi
  1 KB (176 words) - 15:40, 6 September 2022
• Shigaeva 2013 Abstract MiP2013
  ...hondrial ATP-dependent potassium channel in the adaptation of organisms to stress. Mitochondr Physiol Network 18.08. ...ium from ischemia [1], in protecting of the organism against some types of stress and adaptation to it.
  4 KB (632 words) - 11:23, 28 April 2017
• Sies 1997 Exp Physiol
  |title=Sies H (1997) Oxidative stress: oxidants and antioxidants. Exp Physiol 82:291-5. ...avour of the oxidants, potentially leading to damage, is termed 'oxidative stress'. Oxidants are formed as a normal product of aerobic metabolism but can be
  1 KB (168 words) - 13:50, 25 April 2022
• MitoScore
  == MitoScore - Evaluating Mitochondrial Stress in Health and Disease == ...latent mitochondrial dysfunction, at baseline and in response to oxidative stress. As a result, interventions (nutrition, exercise, drugs, novel treatments)
  3 KB (423 words) - 08:23, 15 June 2015
• Bouitbir 2016 Antioxid Redox Signal
  ...on the mitochondrial apoptosis pathway induced by mitochondrial oxidative stress in skeletal muscle using human muscle biopsies as well as ''in vivo'' and ' ...6 myoblasts directly demonstrated the link between mitochondrial oxidative stress following atorvastatin exposure and activation of the mitochondrial apoptos
  3 KB (391 words) - 20:26, 7 March 2020
• Zakharchenko 2013 Int J Biochem Cell Biol
  ...r respiratory chain proteins underlies short-term beneficial physiological stress in mitochondria. Int J Biochem Cell Biol 45:190-200. ...organism. It was first revealed in mitochondria after a single short-time stress episode. The burst of ROS formation was congruous with changes in SDH and K
  3 KB (415 words) - 11:55, 14 December 2015
• Cigliano 2017 Mol Neurobiol
  ...sa S (2017) Short-term fructose feeding induces inflammation and oxidative stress in the hippocampus of young and adult rats. Mol Neurobiol 55:2869-83. ...that fructose treatment induces TNF-alpha production as well as oxidative stress. In conclusion, these results suggest that unbalanced diet, rich in fructos
  3 KB (376 words) - 12:08, 26 June 2019
• Huetter 2007 Aging Cell
  ...ovbro M, Lener B, Prats C, Rabol R, Dela F, Jansen-Dürr P (2007) Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation ...ed that mitochondrial dysfunction is a major source of increased oxidative stress in tissues with high content of mitochondria, such as muscle or brain. Howe
  2 KB (334 words) - 05:23, 8 February 2020
• US CT Storrs Kwon O
  |keyword=Aging, Free Radicals, Oxidative Stress, Vascular function, Mitochondrial-targeted antioxidant (MitoQ), Mitochondri
  452 bytes (53 words) - 15:33, 1 July 2020
• Flores-Herrera 2021 Methods Protoc
  ...ial shape, dynamics and polarity assessment in leaves subjected to diverse stress conditions. |keywords=Abiotic stress, Leaf mesophyll, Plant mitochondria
  1 KB (185 words) - 14:50, 20 March 2023
• Jaber 2020 BM Exp Neurol
  ...ochondrial respiratory chain deficiencies by respirometry: beyond the Mito Stress Test. BM Exp Neurol 328:113282. ...respiratory chain function. This article discusses limitations of the Mito Stress Test, proposes a refined protocol for comparing cell populations that requi
  2 KB (326 words) - 03:19, 24 August 2021
• De Lucas 2014 J Sports Sci
  ..., Latini A (2014) Increased platelet oxidative metabolism, blood oxidative stress and neopterin levels after ultraendurance exercise. J Sports Sci 32:22-30 ...ystemic inflammation (increased neopterin) accompanied by marked oxidative stress, likely by increasing oxidative metabolism (increased oxidative mitochondri
  3 KB (347 words) - 23:21, 29 February 2020
• Leman 2015 Int J Biochem Cell Biol
  ...Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65 ...ings not only highlight the relationship between CI assembly and oxidative stress, but also show the suitability of BN-PAGE analysis in evaluating the conseq
  3 KB (380 words) - 15:32, 9 November 2016
• Anderson 2019 Acta Neuropathol
  ...D10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. Acta Neuropathol 138:103-21. ...rated stress response (mtISR) through mTORC1 activation, with elevation of stress-induced transcription factors, secretion of myokines, upregulated serine an
  2 KB (317 words) - 11:32, 16 August 2019
• Fessel 2013 Am J Respir Cell Mol Biol
  ..., West JD (2013) Hyperoxia synergizes with mutant BMPR2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. Am J Respir Cell Mol Biol 49:7 ...utant animals. These studies demonstrate that oxidant injury and metabolic stress contribute directly to disease development and provide further evidence for
  2 KB (328 words) - 17:25, 4 June 2017
• Wolf 2019 Cells
  ...but increases mitochondrial respiration under conditions of mild oxidative stress. Cells 8:E1289. ...he disease-causing R94Q mutation in MFN2 are more susceptible to oxidative stress, which causes uncoupling of respiration and ATP production possibly by a le
  2 KB (336 words) - 17:04, 13 November 2019
• Campbell 2015 Abstract IOC100
  ...treatment with the mitochondrial-targeted peptide SS-31 reduces oxidative stress and improves muscle function in aged mice. However, whether long-term treat |injuries=Oxidative stress;RONS
  2 KB (331 words) - 09:36, 20 March 2015
• Suravajhala 2017 MiP2017
  ...ld determine the molecular mechanisms [1] further explaining the effect of stress in certain disorders, viz. aging, hypertension, generalized anxiety disorde ...could be spatio-temporal changes that the genome might undergo during such stress conditions which could possibly explain systems biological reasons that lin
  3 KB (362 words) - 09:22, 20 October 2017
• Cortez-Pinto 2009 J Hepatol
  ...xidative stress, reactive oxygen species (ROS) and endoplasmatic reticulum stress playing a major role [1]. Mitochondrial dysfunction seems to be crucial in
  1 KB (175 words) - 22:49, 23 April 2023
• Chen 2019 Ecotoxicol Environ Saf
  ...effects of arsenic trioxide on spermatogonia are associated with oxidative stress, mitochondrial dysfunction, autophagy and metabolomic alterations. Ecotoxic .... We concluded that ATO was toxic to GC-1 spg cells via inducing oxidative stress, mitochondrial dysfunction and autophagy as well as the disruption of norma
  3 KB (378 words) - 18:15, 29 February 2020
• Borisov 2021 Antioxidants (Basel)
  ...and compromise cell viability. To prevent or reduce ROS-induced oxidative stress, bacteria utilize different ROS defense mechanisms, of which ROS scavenging |keywords=Bacteria, Oxidative stress, Reactive oxygen species, Redox enzymes, Terminal oxidases
  1 KB (188 words) - 13:25, 11 August 2021
• Errea 2015 J Neuroinflammation
  ...This prompted us to study the effects of acute inflammation and oxidative stress on the morphology, transport, and function of mitochondria in axons. ...t effects: inflammation mostly reducing retrograde transport and oxidative stress slightly enhancing retrograde transportation.
  3 KB (394 words) - 17:56, 9 November 2017
• Tirichen 2021 Front Physiol
  ...their contribution in chronic kidney disease progression through oxidative stress. Front Physiol 12:627837. https://doi.org/10.3389/fphys.2021.627837 ...of ROS and/or decreased antioxidants defense activity results in oxidative stress (OS), which leads to oxidative damage that affects several cellular compone
  1 KB (188 words) - 11:45, 8 October 2023
• MiP2013 Stress: Hypoxia
  {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Stress::Hypoxia]]
  458 bytes (63 words) - 14:48, 29 November 2016
• MiP2013 Diseases: Aging; senescence
  |?Stress
  458 bytes (63 words) - 14:48, 29 November 2016
• Sengupta 2016 Free Radic Biol Med
  ...ioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89. ...f Rev-erbα with mitochondrial homeostasis and protection against oxidative stress.
  3 KB (393 words) - 15:37, 23 January 2019
• Holloway 2018 Cell Rep
  ...ssociated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48. ...₂O₂ emission and contributes to age-associated redox stress.
  2 KB (301 words) - 13:29, 7 March 2020
• Wolff 2013 J Orthop Res
  ...te MJ, Journot BJ, McKinley TO, Buckwalter JA, Martin JA (2013) Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartil |keywords=Articular Cartilage, Oxidants, Reactive Oxygen Species, Mechanical stress, Glycolysis
  2 KB (274 words) - 14:38, 19 May 2015
• Singh 2015 Free Radic Biol Med
  ...protein adducts, due to lipid peroxidation following DOX-induced oxidative stress, was significantly attenuated by SFN treatment. The respiratory function of |injuries=Oxidative stress;RONS
  2 KB (349 words) - 13:33, 29 May 2018
• John 2021 Life (Basel)
  ...warth FC, Raza H (2021) Effect of aspirin on mitochondrial dysfunction and stress in the pancreas and heart of Goto-Kakizaki diabetic rats. Life (Basel) 11:9 ...redox homeostasis could be the key target in the improvement of oxidative-stress-dependent alterations in mitochondrial functions which, in turn, facilitate
  2 KB (290 words) - 13:45, 24 September 2023
• Wang 2022 Redox Biol
  ...ivation and reperfusion (OGD/R)-induced apoptosis and the activation of ER stress response. Meanwhile, FtMt overexpression rescued OGD/R-induced mitochondria
  3 KB (356 words) - 12:56, 22 November 2022
• Zhang 2020 Chemosphere
  ...hao M, Yuan F, Liu F (2020) Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in ''Mus ...ated. The larvae were exposed to Cd and/or PD, subsequently, the oxidative stress status, mitochondria activity, oxidative phosphorylation efficiency, and su
  2 KB (323 words) - 05:00, 21 November 2023
• DE Ulm Gumpp A
  |keyword=Mitochondrial alterations after traumatic stress and in psychiatric disorders
  530 bytes (65 words) - 12:20, 10 March 2023
• Carling D
  Cellular Stress Group
  456 bytes (58 words) - 09:48, 21 February 2019
• Oellermann 2020 Sci Rep
  ...of whole animal performance. Better understanding of physiological thermal stress cascades will help to improve forecasts of how changing environmental tempe
  2 KB (281 words) - 17:07, 20 January 2020
• Falabella 2015 Oxid Med Cell Longev
  ...eath. Taken together these findings suggest that oxidative and nitrosative stress cooperatively play an important role in driving LHON pathology when excess |keywords=Nitric oxide, LHON, Oxidative and nitrosative stress, PBMC
  2 KB (276 words) - 11:19, 21 January 2020
• Chowdhury Subir Roy
  |topics=nerve, AMPK, sensor neuron, nutrient stress, diabetes, neuropathy
  466 bytes (59 words) - 04:30, 27 February 2023
• Zabielski 2016 Diabetes
  ...muscle, leading to impaired mitochondrial function and increased oxidative stress. |injuries=Oxidative stress;RONS
  3 KB (354 words) - 15:41, 28 March 2018
• Dawson 1993 Am J Physiol
  ...1993) Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am J Physiol 264:C961-7. ...ical formation by complex III is involved in cell killing during reductive stress. In support of this hypothesis, myxothiazol reduced rates of cell killing a
  2 KB (288 words) - 16:31, 3 February 2022
• Cacabelos 2016 Neurobiol Dis
  ...evaluating mechanistic relationships between TDP-43 aggregation, oxidative stress and cellular changes in DHA-related proteins. ...since human neurons exhibited losses of FADS2 and drebrin after oxidative stress. These features (drebrin loss and FADS2 alterations) were also produced by
  4 KB (521 words) - 15:49, 22 March 2016
• Seillier 2015 EMBO Mol Med
  ...metabolic syndrome, through a mechanism involving prevention of oxidative stress by mitochondrial homeostasis regulation. In conclusion, this study highligh |keywords=Autophagy, Diabetes, Mitochondria, Obesity, Oxidative stress, MEF
  2 KB (337 words) - 23:53, 18 March 2018
• Kuzelova 2008 Gen Physiol Biophys
  signs of oxidative stress-decreased alpha-tocopherol/cholesterol in the plasma (''p'' oxidative stress. Administration of simvastatin (10 mg/kg) to the
  2 KB (290 words) - 15:42, 27 March 2018
• Davis 2023 Am J Physiol Regul Integr Comp Physiol .
  ...role of mitochondria-derived ROS in the development of systemic oxidative stress during exercise as well as skeletal muscle diseases such as exertional rhab |keywords=high-resolution respirometry; horse; oxidative stress; skeletal muscle.
  3 KB (363 words) - 22:29, 8 May 2024
• Ferreira 2019 EMBO J
  ...erne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O (2019) Stress signaling and cellular proliferation reverse the effects of mitochondrial m ...on reduces the rate of protein synthesis without eliciting a mitochondrial stress response. Consequently, the rate of translation cannot be recovered and thi
  3 KB (344 words) - 11:24, 3 March 2020
• Sumner 2023 Transl Psychiatry
  ...risk, although more research on these pathways in the context of traumatic stress is needed. Given that many of these mechanisms are closely intertwined, fut
  2 KB (319 words) - 16:31, 8 February 2023
• Lages 2015 PeerJ
  ...(2015) Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells. PeerJ 3:e1486. ...itions, however, when exposed to external agents known to induce oxidative stress, greater susceptibility to DNA damage was observed. Our findings indicate t
  2 KB (285 words) - 15:04, 13 November 2017
• Jing 2015 Int J Biol Sci
  ...ncluded that CoQ10 may protect astrocytes through suppression of oxidative stress, prevention of mitochondrial dysfunction, blockade of mitochondria-mediated |injuries=Oxidative stress;RONS
  2 KB (347 words) - 10:49, 9 November 2016
• Stier 2013 Front Zool
  ...gly, measurements of plasmatic oxidative markers indicated lower oxidative stress in blood of the zebra finch compared to a size-matched mammalian model, the ...tive oxygen species (ROS) production. Interestingly, since blood oxidative stress was lower for our avian model compared to a size-matched mammalian, our res
  3 KB (371 words) - 09:57, 9 November 2016
• Tanaka 2022 Cells
  ...mpromised and to become less resilient under continuous stress. Meanwhile, stress and inflammation have been linked to the activation of the tryptophan (Trp)
  2 KB (329 words) - 13:45, 14 October 2023
• Gainutdinov 2015 Arch Biochem Biophys
  ...in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6. ...mitochondrial function and increases mitochondria stability against Ca(2+) stress.
  2 KB (348 words) - 20:37, 7 March 2020
• Warnsmann 2018 Mech Ageing Dev
  ...function, the mitochondrial permeability transition pore and on oxidative stress in more detail, we used the aging model ''Podospora anserina'' that lacks e ...ondrial dysfunction, Mitochondrial permeability transition pore, Oxidative stress
  2 KB (288 words) - 16:21, 23 March 2018
• Braz-Mota 2018 Sci Total Environ
  ...mage were evaluated. Our results revealed species specificity in metabolic stress responses. An increase of ''ṀO₂'' was noted in cardinal tetra ...abolic rate, Mitochondria respiration, Ornamental Amazon fishes, Oxidative stress, Reactive oxygen species
  3 KB (367 words) - 00:12, 12 January 2022
• Paillard 2009 J Mol Cell Cardiol
  ...gest that during the early minutes of reperfusion, PostC reduces oxidative stress and inhibits mPTP opening, independent of alteration of oxidative phosphory |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  3 KB (354 words) - 16:45, 26 March 2018
• Bassot 2023 Cell Rep
  ...is a key molecular machinery that allows quick metabolic adaptation to ER stress. |keywords=CP: Metabolism, CP: Molecular biology, ER, ER stress, ERO1, MAMs, MERCs, PERK, Bioenergetics, Endoplasmic reticulum, Mitochondri
  2 KB (335 words) - 15:09, 13 March 2024
• Silva-Palacios 2017 Redox Biol
  ...are known to simultaneously initiate different cellular responses against stress by triggering parallel mechanisms, therefore NFκB nuclear accumulation was |mipnetlab=3-Nitropropionic acid, Aging, Nrf2 signaling, Oxidative stress, Tert-Buthylhydroquinone
  2 KB (278 words) - 13:23, 4 July 2017
• Stolf 2018 Biomed Pharmacother
  ...ena SMSC, Acco A (2018) Effects of silymarin on angiogenesis and oxidative stress in streptozotocininduced diabetes in mice. Biomed Pharmacother 108:232-43. ...is or glycemia. In conclusion, treatment with silymarin red uced oxidative stress and inflammation that were induced in the model of streptozotocin-induced d
  2 KB (345 words) - 11:35, 1 October 2018
• Gnaiger 2000 Transplant Proc
  ...inylglycine) are added to organ preservation solutions to reduce oxidative stress.^1,2 GSH is unstable, however, in University of Wisconsin (UW) so |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (194 words) - 13:28, 2 May 2021
• Renshaw 2015 Abstract MiP2015
  ...withstand anoxia-induced stress associated with cross-tolerance to thermal stress? ...estuarine habitats potentially exposing them to severe temperature-induced stress during summer low tides. We measured the effect of each temperature on: i)
  4 KB (506 words) - 15:49, 13 November 2017
• Kumar 2019 Free Radic Biol Med
  ...R, Sandlers Y, Willard B, Hoppel CL, Nagy LE, Dasarathy S (2019) Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysr ...ons (including reduced oxygen consumption, generation of ROS and oxidative stress), increased TCA cycle intermediates, and reversed impaired protein synthesi
  3 KB (406 words) - 11:39, 3 March 2020
• Garratt 2014 Proc Natl Acad Sci U S A
  ...e used a superoxide dismutase knockout mouse to demonstrate that oxidative stress directly impairs investment in morphological (preputial glands) and molecul
  2 KB (287 words) - 14:18, 13 November 2017
• De Oliveira 2011 Neuroscience
  ...ice: Relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress. Neuroscience 197:99-106. ...ive impairment, and cortico-cerebral mitochondrial dysfunctional/oxidative stress. Because of the involvement of such alterations in AD patients, our data re
  3 KB (335 words) - 09:00, 5 May 2020
• Hermes-Lima 2015
  ...ud-Billoud M, Genaro-Mattos TC, Campos ÉG (2015) Preparation for oxidative stress under hypoxia and metabolic depression: Revisiting the proposal two decades ...narios of biological and physiological cellular responses to environmental stress.
  3 KB (444 words) - 12:21, 31 May 2019
• Picard 2012 Am J Respir Crit Care Med
  ...human diaphragms after MV, and the role of mitochondria-derived oxidative stress in the development of VIDD. ...ene and protein expression. In addition, diaphragmatic force and oxidative stress after exposure to MV for 6 hours were evaluated in mice under different con
  3 KB (402 words) - 02:27, 13 September 2023
• Asghar M
  |topics=Aging, GPCRs, Oxidative and inflammatory stress, sodium transporters
  526 bytes (60 words) - 14:02, 13 May 2019
• Rovenko 2015 Comp Biochem Physiol A Mol Integr Physiol
  ...shchak VI (2015) Restriction of glucose and fructose causes mild oxidative stress independently of mitochondrial activity and reactive oxygen species in ''Dr ...mitochondrial activity, mitochondrial density, mtROS production, oxidative stress markers and antioxidant defense in fruit flies fed 0.25%, 4% and 10% glucos
  3 KB (358 words) - 13:44, 27 March 2018
• Sladowska 2021 PLoS Biol
  ...some activity contributes to pro-survival response upon mild mitochondrial stress in ''Caenorhabditis elegans''. PLoS Biol 19:3001302. ...PRmt]) that is mediated by activating transcription factor associated with stress 1 (ATFS-1). The UPRmt increases mitochondrial protein quality control. Mito
  2 KB (283 words) - 12:59, 6 October 2021
• Reactive oxygen species
  ...important in cell signalling, oxidative defence mechanisms and [[oxidative stress]].
  598 bytes (71 words) - 00:19, 18 February 2020
• Ereminas 2017 Biomed Pharmacother
  ...prevention or reduction of necrotic glial cell death during the oxidative stress conditions met in neurodegenerative diseases. However, further elucidation ...l death, Glial cell, Neuroprotection, Oxidative phosphorylation, Oxidative stress
  3 KB (402 words) - 11:36, 27 November 2017
• Dobrowolski 2022 Mol Genet Metab
  ...ical PKU mouse identifies cerebral energy pathway disruption and oxidative stress. https://doi.org/10.1016/j.ymgme.2022.03.004 ...n and serotonin representation), energy dysregulation and tissue oxidative stress expand mechanisms underlying neuropathology.
  3 KB (370 words) - 17:17, 30 November 2022
• FAT4BRAIN FAO-mito-CNS platform
  |?Stress |?Stress
  1 KB (148 words) - 09:14, 14 April 2023
• Barrientos Antoni
  ...ne expression, respiratory supercomplex, hypoxia, redox sensing, oxidative stress
  594 bytes (68 words) - 12:57, 6 July 2023
• Menna-Barreto 2022 Abstract Bioblast
  ...rreto Rubem FS</u> (2022) Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism. Bioblast 2022: BEC Inaugural Conference. In: https:// ...bioenergetics, mitochondrion has a decisive contribution to the oxidative stress, due to the electron leakage from the electron transfer system (ETS). The p
  3 KB (376 words) - 16:23, 20 June 2022
• Cejvanovic V
  |topics=oxidative stress, hemochromatosis
  522 bytes (57 words) - 17:55, 13 February 2018
• Sies 2014 J Biol Chem
  ...H (2014) Role of metabolic H2O2 generation: redox signaling and oxidative stress. J Biol Chem 289:8735-41. ...ged from recent research as a central hub in redox signaling and oxidative stress. Upon generation by major sources, the NADPH oxidases or Complex III of the
  1 KB (216 words) - 15:06, 12 July 2021
• Carraro 2017 Mol Cell Endocrinol
  ...of a high-fat diet, however the actual triggering of endoplasmic reticulum stress was only detected three days later, when IRE-1α was increased. Mitofusin-2 |keywords=Cytokines, Endoplasmic reticulum stress, Hypothalamus, Metabolism, Neurons
  3 KB (400 words) - 13:08, 26 June 2019
• Galli 2021 Front Physiol
  ...tochondrial function are likely to be more profound, because environmental stress during early life can permanently alter cellular physiology and morphology. |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (293 words) - 10:44, 27 December 2021
• Friederich-Persson 2012 Diabetologia
  ...uncoupling. The present study investigates the role of UCP-2 and oxidative stress in mitochondrial oxygen consumption and kidney function in db/db mice as a ...of diabetic nephropathy and the benefits of preventing increased oxidative stress.
  3 KB (413 words) - 16:35, 7 November 2016
• Facundo Heberty Tarso
  :::::'''Keywords:''' mitochondria, oxidative stress, cardiovascular diseases, metabolism
  585 bytes (71 words) - 10:29, 8 May 2024
• Schiffer 2013 Abstract MiP2013
  ...ing physical exercise in humans [1] and contribute to attenuated oxidative stress in animal models of disease [2]. Nitrate accumulates in saliva and is bioac ...of dietary nitrate on basal metabolic rate (BMR) and markers of oxidative stress in man using a double-blind, randomized cross over design. 15 young healthy
  3 KB (400 words) - 16:20, 27 March 2018
• Huetter 2002 Mol Biol Rep
  ...low-oxygen levels, whereas further pronounced depression induces energetic stress under hypoxia.
  1 KB (198 words) - 08:12, 11 January 2024
• Verma 2023 Int J Mol Sci
  ...mitochondrial dysfunction mediated by neuroinflammation through oxidative stress. Int J Mol Sci 24:950. https://doi.org/10.3390/ijms24020950 ...t ''P. gingivalis''-LPS causes mitochondrial dysfunction through oxidative stress and inflammatory events in neurodegenerative diseases.
  2 KB (303 words) - 15:28, 13 March 2024
• De Andrade 2015 Exp Cell Res
  ...of cholestatic rats, increasing oxidative capacity and reducing oxidative stress, which, in turn, contribute to liver function recover. |injuries=Oxidative stress;RONS
  2 KB (316 words) - 11:04, 8 November 2016
• Bravo-Sagua 2019 MiPschool Coimbra
  ...g of metabolism modulated by ER–mitochondria communication during early ER stress. ...y mechanism in the modulation of mitochondrial metabolism. During early ER stress, this communication increases as an adaptive mechanism [1]. The signalling
  4 KB (590 words) - 14:12, 18 June 2019
• Champigny 2018 Mar Drugs
  ...acylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453. ...ides (MAG, both EPA and DHA) on the mitochondrial metabolism and oxidative stress of a short-lifespan model, ''Drosophila melanogaster'', sampled at five dif
  2 KB (300 words) - 11:09, 25 July 2019
• De Godoy 2018 J Biol Chem
  ...-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. J Biol Chem 293:1957-75 ...rived extracellular vesicles protect neurons against AβO-induced oxidative stress and synapse damage, revealed by loss of pre- and postsynaptic markers. Prot
  3 KB (371 words) - 10:34, 26 February 2018
• Kaspar 2021 Sci Adv
  ...Larsson O, Topisirovic I, Trifunovic A (2021) Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv 7:0971. ...interplay between three transcription factors regulating the mitochondrial stress response: CHOP, C/EBPβ, and ATF4. We show that CHOP acts as a rheostat tha
  2 KB (291 words) - 09:13, 5 August 2021
• Hoel 2017 MiPschool Obergurgl
  |title=[[File:HoelF.jpg|left|90px|Hoel Fredrik]] A study on mitochondrial stress responses due to OXPHOS inhibition. ...dria through biogenesis. These processes are crucial for adaptation during stress conditions, and have also been linked to diseases such as Parkinson’s dis
  2 KB (324 words) - 14:40, 27 March 2018
• Li 2017 Oxid Med Cell Longev
  ...mitochondria were transferred to the injured hMSCs via TNTs, the oxidative stress was decreased, and the mitochondrial membrane potential of the H_{2</sub |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (301 words) - 13:27, 5 June 2018
• Cahova 2014 Appl Physiol Nutr Metab
  ...on alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. Appl Physiol Nutr Metab ...ted disorders, particularly fatty acid oxidation, steatosis, and oxidative stress in the liver, could be attenuated by carnitine supplementation. The effect
  3 KB (374 words) - 15:43, 7 November 2016
• Jelenik 2013 Eur Heart J
  ...ase and insulin resistance are associated with increased cardiac oxidative stress in mice. Eur Heart J 34:P5045. ...e investigated how NAFL and insulin resistance relate to cardiac oxidative stress and mitochondrial oxidative capacity in mice.
  3 KB (452 words) - 13:45, 7 March 2020
• Stadlmann 1999 Transplant Proc
  ...G, Hengster P, Margreiter R, Gnaiger E (1999) Does H2O2-mediated oxidative stress reproduce mitochondrial cold preservation/reoxygenation injury in endotheli |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (213 words) - 09:24, 16 June 2015
• Tronstad 2012 Abstract Bioblast
  ...WJ, Tronstad KJ (2012) Mitochondrial morphology and biogenesis in cellular stress. Mitochondr Physiol Network 17.12. ...uding mitochondrial respiration, may represent an important determinant of stress tolerance. Using new tools to study these phenomena is therefore important
  4 KB (523 words) - 17:20, 3 February 2016
• Levitan 2015 Proc Natl Acad Sci U S A
  ...iate metabolism in the diatom ''Phaeodactylum tricornutum'' under nitrogen stress. Proc Natl Acad Sci U S A 112:412-7. ...d reductants is used to synthesize lipids. To further examine how nitrogen stress triggers the remodeling process, we knocked down the gene encoding for nitr
  2 KB (305 words) - 15:29, 8 August 2023
• Lautrup 2019 Cell Metab
  ...le NAD+-dependent enzymes are involved in synaptic plasticity and neuronal stress resistance. Here, we review emerging findings that reveal key roles for NAD
  2 KB (215 words) - 22:47, 3 November 2023
• Tillmans 2018 Thesis
  ...hoblastic leukemic cell lines ''in vitro'' through assessment of oxidative stress, DNA-fragmentation, mitochondrial function and apoptosis induction. The stu ...le cell gel electrophoresis (comet assay), protein expression of oxidative stress markers, induction of nitric oxide Synthases and expression of pro- and ant
  3 KB (468 words) - 18:32, 31 January 2020
• Govindaraj 2011 Mitochondrion
  ...n periodontal tissues but not in the blood, suggesting a role of oxidative stress on periodontal tissues. Thus, our functional and genetic analysis provided |injuries=Oxidative stress;RONS
  1 KB (194 words) - 16:18, 19 March 2015
• Larsen 2016 FASEB J
  ...ase in protein abundance of catalase. In this study, a novel mitochondrial stress response was highlighted where accumulation of citrate acted to preserve th |injuries=Oxidative stress;RONS
  3 KB (366 words) - 16:42, 7 March 2020
• Pereira 2017 EMBO J
  ...nsitivity. OPA1-elicited mitochondrial dysfunction activates an integrated stress response that locally induces muscle atrophy, but via secretion of FGF21 ac |keywords=ER stress, FGF21, OPA1, Mitochondrial dysfunction, Skeletal muscle
  2 KB (284 words) - 10:49, 14 January 2020
• Boeck Christina
  |topics=psychopathological stress
  558 bytes (62 words) - 09:24, 10 August 2020
• Shelchkova N
  |topics=Cell respiration, hypoxia, oxidative stress, Ischemia-reperfusion injury, mitochondrial pathways, respiratory control
  596 bytes (65 words) - 16:40, 13 June 2017
• Vandenberg 2022 Am J Physiol Cell Physiol
  ...ation of astrocyte redox balance in FXS, which may contribute to oxidative stress. Astrocyte function and mitochondrial bioenergetics are significantly influ |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (322 words) - 06:32, 28 July 2023
• Chlororespiration
  ...protection mechanism and could be involved in protecting against oxidative stress.
  2 KB (227 words) - 09:42, 11 September 2021
• Radenkovic 2017 Biochem Pharmacol
  ...n of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:4 ...reductase (TrxR) and glutathione peroxidase (GPx), resulting in oxidative stress and the initiation of a pro-apoptotic cascade. The effect of Auranofin expo
  3 KB (401 words) - 08:46, 27 February 2018
• Christen 2018 Free Radic Biol Med
  ...ry capacity, have a more fragile heart and will be more prone to oxidative stress and HF, and less tolerant to temperature changes and other stressors. Our r
  3 KB (397 words) - 12:49, 26 February 2018
• Hoppel 2021 Front Physiol
  ...ultramarathon running on mitochondrial function of platelets and oxidative stress parameters: a pilot study. https://doi.org/10.3389/fphys.2021.632664 ...ential post-race as a protective consequence of the race-related oxidative stress and potential threat to the kidney. Our findings point toward an interrelat
  4 KB (517 words) - 15:51, 7 June 2022
• Walczak 2018 FASEB J
  ...in the center of cellular metabolism, play a pivotal role in adaptation to stress conditions. We found that mitochondrial dysfunction and adaptation processe
  2 KB (327 words) - 10:27, 29 July 2019
• Wojtala 2014 Abstract MiP2014
  ...chondrial metabolism through regulation of cellular responses to oxidative stress. A low level of p66Shc protein or its complete ablation protects against nu ...oxidative stress. The status of the antioxidant defense system, oxidative stress markers and the p66Shc-Ser36 phosphorylation pathway were measured in these
  3 KB (474 words) - 09:00, 18 March 2020
• Stadlmann 2002 Transplantation
  ...er A, Kuznetsov AV, Margreiter R, Gnaiger E (2002) H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cult |abstract=Oxidative stress to vascular endothelium plays an important role in cold ischemia-reperfusio
  2 KB (305 words) - 14:10, 27 December 2021
• Iftikar 2013 PLoS One
  ...ot fish hearts? Understanding the role of mitochondrial function with heat stress in ''Notolabrus celidotus''. PLoS One 8:e64120. ...HF in heat stressed hearts in fish and play a significant role in thermal stress tolerance, and perhaps limit species distributions by contributing to HF.
  3 KB (384 words) - 16:41, 25 January 2021
• Scatena 2019 Curr Med Chem
  ...blocking the typical cancer progression. The main aim of this review is to stress some neglected aspects of oxidative mitochondrial metabolism of cancer cell ...ic Biomarkers, Metabolism, Mitochondria, Molecular therapeutics, Oxidative stress, ROS
  3 KB (354 words) - 15:33, 7 May 2020
• Kucharska 2000 Physiol Res
  |abstract=Mitochondrial dysfunction and oxidative stress participate in the development of diabetic complications, however, the mech ...ds=Diabetes mellitus, Mitochondria, Alpha-tocopherol,Coenzyme Q, Oxidative stress
  3 KB (358 words) - 10:33, 7 May 2015
• Jia 2018 Circ Res
  ...one system activation, cardiac autonomic neuropathy, endoplasmic reticulum stress, microvascular dysfunction, and a myriad of cardiac metabolic abnormalities |injuries=Oxidative stress;RONS, Mitochondrial disease
  3 KB (330 words) - 16:09, 24 February 2020
• Aon 2010 Biochim Biophys Acta
  ...brane potential, Psim), whereas intact cardiac cells can display oxidative stress either when mitochondria become more uncoupled (i.e., low Psim) or when mit
  2 KB (323 words) - 21:46, 24 September 2021
• Cassina 2015 Biol Reprod
  ...ion respirometry, ROS production and footprints of oxidative and nitrative stress processes in intact human sperm cells. We showed that mitochondrial dysfunc |keywords=Mitochondria, Reactive oxygen species, Nitro-oxidative stress, Sperm motility and transport, Male infertility
  2 KB (341 words) - 17:12, 9 November 2017
• Di Meo 2016 Oxid Med Cell Longev
  ...recent data, besides confirming the mitochondrial role in tissue oxidative stress and protection, show interplay between mitochondria and other ROS cellular
  2 KB (229 words) - 19:30, 7 April 2022
• Mukhina I
  |topics=Cell respiration, hypoxia, oxidative stress, Ischemia-reperfusion injury, mitochondrial pathways, respiratory control
  592 bytes (68 words) - 16:41, 13 June 2017
• Adeyemi 2019 Ecotoxicol Environ Saf
  ...LC, Antunes LMG, Barbosa F Jr (2019) Cytotoxicity, mutagenicity, oxidative stress and mitochondrial impairment in human hepatoma (HepG2) cells exposed to cop ...ed assays), mutagenicity (cytokinesis-block micronucleus assay), oxidative stress (total reactive oxygen species and superoxide anion production) and mitocho
  2 KB (319 words) - 11:15, 7 March 2020
• Lozano 2019 Oxid Med Cell Longev
  ...lts point to the potential of this strategy for the treatment of oxidative stress-based cardiac diseases. |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (295 words) - 16:30, 14 October 2023
• Reguis Yadao 2018 Thesis
  ...patients, due mostly to mitochondrial dysfunction and resulting oxidative stress. Endurance exercise has been firmly established as a way to reduce diabetes ...rdiovascular disease, Vascular disease, Reactive oxygen species, Oxidative stress, Mitochondria, Mitochondrial dysfunction, Oxidative phosphorylation, Exerci
  3 KB (338 words) - 16:39, 31 January 2019
• Bradshaw 2019 Nutrients
  ...itochondrial NADPH plays an important role in the protection against redox stress and cell death and mitochondrial NADPH-utilizing thioredoxin reductase 2 le
  2 KB (245 words) - 10:56, 4 February 2022
• Kirkman 2015 Abstract MiPschool Greenville 2015
  ...ized by reduced nitric oxide bioavailability as a consequence of oxidative stress. Damaged and dysfunctional mitochondria as a result of CKD are likely a lar ...Improving mitochondria health and reducing mitochondria derived oxidative stress may be a potential therapeutic target for improving endothelial function in
  2 KB (288 words) - 16:07, 20 July 2015
• Esselun 2019 Oxid Med Cell Longev
  ...ion, our findings show that SIL A protects against SNP-induced nitrosative stress at the level of mitochondria making it potentially beneficial against neuro
  2 KB (320 words) - 14:30, 5 December 2019
• Quiros 2016 Nat Rev Mol Cell Biol
  ...PM, Mottis A, Auwerx J (2016) Mitonuclear communication in homeostasis and stress. Nat Rev Mol Cell Biol 17:213-26.
  352 bytes (48 words) - 22:37, 16 January 2021
• Loor 2011 Biochim Biophys Acta
  ...pa GB, Guzy RD, Vanden Hoek TL, Schumacker PT (2011) Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochim Biophys Acta ...of Mn-SOD or mito-PHGPx. These findings suggest that mitochondrial oxidant stress causes oscillation of the mPTP prior to reperfusion. Cytochrome c release f
  3 KB (384 words) - 18:01, 13 April 2022
• Plecita-Hlavata 2009 Int J Biochem Cell Biol
  ...ter 24 h. In rotenone-inhibited HepG2 cells (i.e., already under oxidative stress) MitoQ₁₀ sharply decreased rotenone-induced ''J''_m, b |injuries=Oxidative stress;RONS
  3 KB (405 words) - 15:40, 13 November 2017
• Van Den Brink 2018 PLoS Genet
  ...of LD may be toxic for photoreceptors cells of the retina under oxidative stress. Collectively, these findings indicate that FATP-mediated LD formation in R
  3 KB (377 words) - 11:40, 29 October 2018
• De Souza 2012 Lipids
  ...are ER, Vercesi AE, Passarelli M (2012) Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated a ...generation was not able to restore ABCA-1 levels. Inhibition of oxidative stress induced by AGE-albumin prevents disturbances in reverse cholesterol transpo
  2 KB (332 words) - 09:16, 29 August 2022
• Koliaki 2013 Mol Cell Endocrinol
  ...ter lipid storing and oxidative capacity, resulting in increased oxidative stress, which in turn could deteriorate hepatic mitochondrial function in chronic
  2 KB (219 words) - 11:41, 3 February 2014
• Dai 2011 Circ Res
  ...g YJ, Prolla TA, Santana LF, Rabinovitch PS (2011) Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpress ...ral cardiovascular diseases; however, the roles of mitochondrial oxidative stress and DNA damage in hypertensive cardiomyopathy are not well understood.
  2 KB (319 words) - 15:40, 19 March 2015
• Jezek 2015 Antioxid Redox Signal
  ...-activated mitochondrial phospholipase iPLA2γ prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GP ...ic lipotoxicity evolves from acute free fatty acid (FA)-mediated oxidative stress, unprotected by antioxidant mechanisms. Since mitochondrial uncoupling prot
  3 KB (386 words) - 14:47, 13 November 2017
• Alfatni 2020 J Clin Med
  ...blood mononuclear cells and platelets mitochondrial dysfunction, oxidative stress, and circulating mtDNA in cardiovascular diseases. J Clin Med 9 pii:E311. ...ible adjunct of PBMCs' and platelets' mitochondrial dysfunction, oxidative stress, and circulating mtDNA as biomarkers of CVD diagnosis and prognosis. This n
  2 KB (328 words) - 20:19, 7 March 2020
• Gonzalez-Flecha 1993 J Clin Invest
  ...echa B, Cutrin JC, Boveris A (1993) Time course and mechanism of oxidative stress and tissue damage in rat liver subjected to in vivo ischemia-reperfusion. J
  404 bytes (54 words) - 17:13, 16 January 2021
• Coleman 2018 Sci Rep
  ...down the functions controlled by Nrf2 in muscle mitohormesis and oxidative stress defense during mitochondrial OXPHOS inefficiency.
  2 KB (301 words) - 12:54, 21 February 2023
• Dixit 2017 Free Radic Biol Med
  ...re often depleted through mitochondrial dysfunction and elevated oxidative stress. ...Alzheimer’s disease, Ascorbate, Energy production, Mitochondria, Oxidative stress
  3 KB (338 words) - 17:48, 20 December 2017
• Darrah-Wiedemeier 2015 Graduate Theses and Dissertations
  ...otects maize seedlings against mitochondrial damage due to low temperature stress. In ...ios, respiration rates, or respiration rate ratios. In the low temperature stress study, there was a hybrid by treatment interaction. Stamina did not effect
  3 KB (490 words) - 16:19, 5 July 2023
• O2k-Publications: Cardiovascular diseases
  |?Stress |?Stress
  1 KB (196 words) - 10:59, 11 November 2016
• Kenny 2019 Circ Res
  ...ribed. These include oxidative stress, inflammation, endoplasmic reticulum stress, aberrant insulin signaling, accumulation of advanced glycated end-products |injuries=Cell death, Oxidative stress;RONS
  3 KB (359 words) - 16:45, 24 February 2020
• Mendonca AP
  |topics=Oxidative stress, tumors, hemorrhage, brain
  612 bytes (81 words) - 17:57, 13 February 2018
• Nabeebaccus 2017 JCI Insight
  ...ograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. JCI Insight 2:96184. ...ams cardiac substrate metabolism to favorably modify adaptation to chronic stress. Our results also suggest that increased fatty acid oxidation in the chroni
  2 KB (308 words) - 11:02, 14 January 2020
• Engin Ayse Basak
  ...Toxicology and also Immunology. My research is mainly focused on oxidative stress, tryptophan metabolism, nanoparticles, neurodegenerative disorders, immunot
  2 KB (225 words) - 19:54, 2 March 2020
• Kwak 2012 Free Radic Biol Med
  ...n impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207. ...ulated maximal mitochondrial respiratory capacity, mitochondrial oxidative stress, and apoptosis in primary human skeletal myotubes, suggesting that mitochon
  3 KB (381 words) - 17:27, 25 February 2020
• Ambrosio 2014 Free Radic Biol Med
  ...sed mice. These pathological changes from a possible maladaptive oxidative stress response provide insight into declines in muscle functioning caused by expo |keywords=Metabolism, Mitochondria, Resistance to stress, Free radicals
  2 KB (329 words) - 12:13, 28 March 2018
• Bleier 2014 Free Radic Biol Med
  ...-dependent dual role of mitochondrial ROS in redox signaling and oxidative stress. |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (340 words) - 15:34, 7 November 2016
• Richter 2019 Life Sci Alliance
  ...Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ (2019) Mitochondrial stress response triggered by defects in protein synthesis quality control. Life Sc ...itochondrial protein synthesis with chloramphenicol completely blocks this stress response. Together, our data establish a mechanism linking major cell biolo
  2 KB (317 words) - 09:21, 18 March 2020
• Zheleznova 2012 Physiol Genomics
  ...gen utilization in salt-induced hypertension and renal medullary oxidative stress. ..., oxygen utilization, salt-induced hypertension, renal medullary oxidative stress
  2 KB (315 words) - 14:42, 13 February 2015
• Mazzoli 2021 Antioxidants (Basel)
  ...m the diet reverses inflammation, mitochondrial dysfunction, and oxidative stress in hippocampus. Antioxidants (Basel) 10:487. ...rt-term fructose-rich diet induced mitochondrial dysfunction and oxidative stress, associated with an increased concentration of inflammatory markers and dec
  2 KB (324 words) - 13:29, 12 July 2021
• McManus 2016 Abstract MitoFit Science Camp 2016
  |abstract=Mitochondrial dysfunction and oxidative stress are among the earliest and most frequently reported pathogenic changes in l ...sation for mitochondrial genetics, bioenergetic dysfunction, and oxidative stress in the pathogenesis of age-related disease.
  4 KB (502 words) - 09:02, 1 July 2016
• Anderson 2009 J Am Coll Cardiol
  ...It has been proposed that derangements in cardiac metabolism and oxidative stress may underlie the progression of this comorbidity, but scarce evidence exist ...sed substrates, depleted glutathione, and evidence of persistent oxidative stress in their atrial tissue.
  3 KB (416 words) - 16:40, 14 October 2019
• Lu 2022 J Cosmet Dermatol
  ...on efficiency, and block the massive loss of skin nutrients and net energy stress. Furthermore, LQ can promote collagen synthesis and keratinocyte proliferat |injuries=Oxidative stress;RONS
  2 KB (314 words) - 19:23, 24 February 2023
• Borras 2010 Biochim Biophys Acta
  ...st whether estradiol directly affects mitochondria by preventing oxidative stress and protecting frail mitochondria. Incubation with estradiol at normal intr |keywords=Estrogenic compound, Oxidative stress, Genistein, Cytochrome c, Mitochondria, Antioxidant
  2 KB (244 words) - 16:39, 12 October 2016
• Dubinski 2018 Biochim Biophys Acta
  ...sembly mutants display unexpected changes in markers of cellular oxidative stress at stationary phase. Our results suggest that mitochondria may not be a maj |keywords=Cytochrome c oxidase (complex IV) assembly, Mitochondria, Oxidative stress, Stationary phase, Yeast
  2 KB (233 words) - 13:10, 25 April 2018
• McCullough 2017 Pharmacol Ther
  ...e-based technologies for the study of mitochondrial dysfunction, oxidative stress and fibrogenesis in NAFLD. We highlight the limitations of current methodol |keywords=Citric acid cycle, Fatty acid oxidation, Fibrosis, NAFLD, Oxidative stress, Stable isotopes
  2 KB (236 words) - 16:46, 27 March 2018
• Chen 2020 Biochim Biophys Acta Mol Basis Dis
  ...alters gene expression, mitochondrial content, inflammation and oxidative stress without affecting high-fat diet-induced obesity or insulin resistance. Bioc ...ial content and function and elevated inflammatory signaling and oxidative stress.
  3 KB (396 words) - 17:54, 1 July 2020
• Palacka 2021 Int J Mol Sci
  ...The impaired mitochondrial function can contribute to increased oxidative stress by triggering the reverse electron transport from the CoQ₁₀ cycl |keywords=Mitochondrial bioenergetics, Oxidative stress, Platelets, Reprogramming, Urothelial carcinoma
  3 KB (457 words) - 22:56, 23 September 2023
• Bombaca 2020 Free Radic Biol Med
  ...tabolic processes of ''S. culicis'' are modulated in response to oxidative stress conditions, providing new perspectives on the biology of the trypanosomatid ...=Antioxidant system, Ascorbate peroxidase, Energetic metabolism, Oxidative stress, Pentose phosphate pathway
  3 KB (386 words) - 15:43, 11 February 2020
• Marcinek 2016 Abstract MitoFit Science Camp 2016
  |title=Targeting mitochondrial redox stress reveals two phases for reversal of mitochondrial dysfunction in aged mouse ...hondrial membrane, to test the interaction between mitochondrial oxidative stress, energetics, and muscle performance in aged mice.
  4 KB (631 words) - 04:40, 12 February 2020
• Duran-Gueell 2023 FASEB J
  ...d for the effective protection of liver cells from mitochondrial oxidative stress induced by TNFα. These findings emphasize the importance of maintaining th ...atocytes, Liver injury, Mitochondrial dysfunction, Mitochondrial oxidative stress, Mitochondrial respiration, Tricarboxylic acid cycle
  4 KB (478 words) - 19:05, 15 March 2023
• Oparka 2014 Abstract MiP2014
  ...covered. Involvement of this protein in cell death is related to oxidative stress. Phosphorylation of p66Shc at Ser36 can be activated by extracellular or in |injuries=Oxidative stress;RONS
  3 KB (380 words) - 16:44, 23 February 2015
• Hunter-Manseau 2024 Insect Sci
  ...tments to restore cellular homeostasis are crucial to survive this type of stress. In this study, we exposed male ''Drosophila melanogaster'' to two modulate ..., Fasting, High‐fat diet, Metabolic flexibility, Mitochondrial metabolism, Stress response
  3 KB (359 words) - 14:53, 4 April 2024
• ES Madrid Cadenas S
  |keyword=hypoxia, ischaemic heart disease, nitric oxide, oxidative stress, uncoupling proteins (UCPs)
  723 bytes (96 words) - 12:58, 4 May 2018
• Ying 2008 Antioxid Redox Signal
  ...NAD and NADP profoundly affect aging-influencing factors such as oxidative stress and mitochondrial activities, and NAD-dependent sirtuins also mediate the a
  2 KB (254 words) - 17:54, 1 February 2022
• Wang 2023 Clin Exp Pharmacol Physiol
  ...myocyte function by increasing antioxidant capacity and reducing oxidative stress in cryopreserved rat hearts during a prolonged preservation time, resulting ...itochondrial inhibitor, Myocardial ischaemia-reperfusion injury, Oxidative stress
  2 KB (330 words) - 15:22, 6 December 2023
• De Oliveira 2020 Cells
  ...op growth of tumors that shifted to mitochondrial FAO to survive oxidative stress and nutrient scarcity.
  3 KB (380 words) - 18:17, 12 September 2022
• Dirks 2020 J Physiol
  ...ssion to mitochondrial O₂ consumption, and markers of oxidative stress were not altered following bed rest. Altogether, while bed rest impairs mit |injuries=Oxidative stress;RONS
  2 KB (348 words) - 11:09, 20 March 2020
• Cervinkova 2008 Physiol Res
  ...or for the regeneration process in the necrotic liver damaged by oxidative stress. |injuries=Oxidative stress;RONS
  2 KB (223 words) - 11:12, 18 March 2020
• Li 2015 Sci Rep
  ...tory dysfunctions of PBMCs link with the cellular inflammation / oxidative stress and cardiac disturbance in early-stage HF. |injuries=Oxidative stress;RONS
  3 KB (358 words) - 23:30, 29 February 2020
• Castellano-Gonzalez 2019 Neurotox Res
  ...in neurodegenerative disease as neurons are highly sensitive to oxidative stress and mitochondrial impairment. ...3-monooxygenase, Kynurenine pathway, Mitochondrial dysfunction, Oxidative stress
  2 KB (314 words) - 13:15, 14 August 2019
• Moreno-Ortega 2016 Neurotox Res
  ...uroprotective effect of the novel compound ITH33/IQM9.21 against oxidative stress and Na⁺ and Ca²⁺ overload in motor neuron-like NSC-34 ...bindin-D28k levels. Therefore, ITH33 was neuroprotective against oxidative stress and Na⁺/Ca²⁺ overload, both of which are involved in
  2 KB (345 words) - 13:42, 10 October 2016
• Odorcyk 2021 Mol Neurobiol
  ...CA (2021) Differential age-dependent mitochondrial dysfunction, oxidative stress, and apoptosis induced by neonatal hypoxia-ischemia in the immature rat bra ...n, reduced TCA cycle enzymes, and RC activities and induction of oxidative stress in this group of animals. Considering that HIP3 and the sham animals showed
  2 KB (337 words) - 16:13, 2 December 2021
• Storey 1979 Can J Zool
  ...oncentration in cephalopod blood is modulated in response to physiological stress and that octopine metabolism is closely integrated with the metabolism of g
  2 KB (276 words) - 10:08, 9 November 2016
• O2k-Publications: mt-Biogenesis;mt-density
  |?Stress |?Stress
  1 KB (198 words) - 10:54, 11 November 2016
• Napa 2017 Int J Dent
  |abstract=Oral inflammatory pathologies are linked to increased oxidative stress, thereby partly explaining their relevance in the etiology of systemic diso ...TP generation. These findings provide insight into the nature of oxidative stress in oral inflammatory pathologies.
  2 KB (314 words) - 11:46, 9 February 2022
• US AK Fairbanks Coker RH
  |keyword=mitigation of metabolic stress in clinical conditions: obesity, diabetes, sarcopenia and alcohol abuse
  594 bytes (82 words) - 08:47, 11 May 2018
• Ahmad 2017 Springer, Cham
  ...ies (ROS) in the reproductive system. In: Agarwal A, et al (eds) Oxidative stress in human reproduction. Springer, Cham. https://doi.org/10.1007/978-3-319-48 ...high concentration, overwhelming the antioxidant defense system, oxidative stress results, and this may lead to cellular dysfunction via lipid peroxidation,
  2 KB (249 words) - 01:17, 9 November 2023
• Stankova 2010 Toxicol In Vitro
  ...Mitochondria are affected by TAA secondarily as a consequence of oxidative stress. Oxidation of the NADH-dependent substrates of respiratory Complex I is sig |injuries=Oxidative stress;RONS
  2 KB (341 words) - 10:58, 18 March 2020
• Valles 2016 Aging Cell
  ...ounds rescue neurons from Abeta-induced cell death by preventing oxidative stress, which in turn inhibits the activation of p38, protecting neurons from cell
  2 KB (245 words) - 09:15, 14 October 2016
• Hand 2022 Abstract Bioblast
  ...own of bioenergetics: Protection of macromolecules and survivorship during stress. '''Bioblast 2022: BEC Inaugural Conference.''' In: https://doi.org/10.2612 ...ls can be extended to a desiccation-sensitive, whole organism during water stress.
  5 KB (720 words) - 08:29, 28 July 2022
• Borras 2003 Free Radic Biol Med
  |abstract=We have investigated the differential mitochondrial oxidative stress between males and females to understand the molecular mechanisms enabling f |injuries=Oxidative stress;RONS
  2 KB (269 words) - 16:54, 17 October 2016
• Santos-Silva 2023 Transl Psychiatry
  ...ial pathways associated with distinct adolescent behavioral phenotypes and stress response. https://doi.org/10.1038/s41398-023-02648-3 ...le also underscoring the detrimental functional consequences of adolescent stress on the PFC.
  3 KB (418 words) - 16:23, 21 November 2023
• Iglesias-Gonzalez 2016 Mol Neurobiol
  ...contribute to explain both the ability of aluminium to generate oxidative stress and its suggested potential to act as an etiological factor by promoting th |keywords=Aluminium, High-resolution respirometry, Mitochondria, Oxidative stress, Parkinson’s disease, Rat brain
  2 KB (335 words) - 14:42, 13 November 2017
• Vaka 2017 Hypertension
  ...y to fully understand the contribution of mitochondrial mediated oxidative stress to pathology of PE.
  2 KB (333 words) - 09:36, 25 September 2017
• Moisoi 2017 Abstract MITOEAGLE Barcelona
  Mitochondria are under stress from external factors as well as from their own respiratory activity. Maint ...harbouring mutations in MQC pathways to address the role of mitochondrial stress signaling and mitochondria homeostasis in PD.
  2 KB (259 words) - 13:37, 27 March 2018
• Quoilin 2014 Dissertation
  ...Surprisingly,this cellular respiration alteration persists even after the stress factor is removed. We suggested that this irreversible decrease in renal ox |injuries=Cell death, Ischemia-reperfusion, Oxidative stress;RONS
  4 KB (581 words) - 12:21, 14 December 2015
• Marinho 2018 Evid Based Complement Alternat Med
  ...ng mitochondrial dysfunction, steatosis, acute inflammation, and oxidative stress.
  2 KB (335 words) - 11:33, 13 July 2018
• Krycer 2019 J Biol Chem
  ...sed respiration unless glucose is present; and (c) mitochondrial oxidative stress must precede the insulin stimulus to cause insulin resistance, explaining w ...s=Adipocyte, Glucose, Insulin, Insulin resistance, Mitochondria, Oxidative stress, Respiration
  3 KB (364 words) - 15:54, 15 January 2020
• Barakat 2013 Microbiologyopen
  ...h a complex III-dependent mechanism. Therefore, a combination of oxidative stress and respiration disturbance could partly explain aerobic PYO toxicity. Surp |keywords=Saccharomyces cerevisiae , Aerobiosis, Anaerobiosis, Oxidative stress, Phenazine, Pyocyanin, Yeast mutants
  3 KB (364 words) - 12:05, 8 November 2016
• O2k-Publications: Mitochondrial disease
  ...ions]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Inherited]] OR [[Stress::Mitochondrial disease]] ...acts]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Inherited]] OR [[Stress::Mitochondrial disease]]
  2 KB (206 words) - 16:38, 13 January 2023
• Gutsaeva 2008 J Neurosci
  |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  526 bytes (65 words) - 13:53, 16 June 2015
• Fetterman 2013 Biochem J
  the pathological stress of cardiac volume overload which is stress.
  2 KB (343 words) - 16:31, 7 November 2016
• Wei Yau-Huei
  ...ransfer pathway, stem cells, iPSC, mitochondrial disease, mtDNA, oxidative stress, metabolic reprogramming
  733 bytes (87 words) - 16:03, 29 November 2021
• Kukat 2014 PLoS Genet
  ...t result in increased oxidative stress. Normal levels of ROS and oxidative stress could also be a result of an active compensatory mechanism such as a mild i |injuries=Oxidative stress;RONS
  2 KB (336 words) - 14:44, 20 June 2023
• Rindler 2013 J Biol Chem
  ...lipids for energy, contributes to these diseases. The effects of oxidative stress are mitigated by an endogenous antioxidant enzyme network, but little is kn |injuries=Oxidative stress;RONS
  2 KB (352 words) - 15:38, 30 April 2015
• Shirakawa 2019 Sci Rep
  ...vely correlated with urinary 8-hydroxydeoxyguanosine, a systemic oxidative stress marker, in CHF patients. Importantly, mitochondrial ROS generation in PBMCs |injuries=Oxidative stress;RONS
  2 KB (346 words) - 14:41, 5 July 2023
• Vandermeeren 2019 MiP2019
  ...ess impact and management can partly explain tolerance to high temperature stress in fish. ...tween heart lipid composition and individual tolerance to an acute thermal stress, pointing out to mitochondria as a likely mechanistic cause of general home
  3 KB (472 words) - 13:52, 1 October 2019
• Yang 2022 J Cleaner Production
  ...and 47.4 ± 2.1%, respectively. The proteomics analysis revealed that under stress conditions, microalgae altered cellular components such as the nucleus and
  2 KB (254 words) - 11:55, 9 November 2023
• Yang 2020 Transl Neurodegener
  ...asive treatment that promotes energy production and reduces both oxidative stress and inflammation, and has garnered increasing attention in recent years. MB
  2 KB (257 words) - 19:17, 25 April 2023
• Hagl 2013 Pharmacol Res
  ...utraceutical for the prevention of mitochondrial dysfunction and oxidative stress in brain aging and neurodegenerative diseases. ...ration, Cardiolipin, Mitochondrial dynamics, Nitrosative stress, Oxidative stress, Rice bran extract
  2 KB (351 words) - 10:49, 27 March 2018
• Favia 2019 J Clin Med
  ...a leading role in opposing the high ASL glucose level as well as oxidative stress in CF.
  2 KB (268 words) - 00:34, 9 October 2023
• Khera 2015 Placenta
  ...as shown that selenium can protect trophoblast mitochondria from oxidative stress. This report examines mitochondrial function and content in trophoblasts su
  2 KB (235 words) - 08:54, 27 February 2018
• Da Silva 2017 Neurotox Res
  ...disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90. ...idation and GSH levels, making unlikely a secondary induction of oxidative stress through overstimulation of glutamate receptors. In contrast, KAA and AAA di
  3 KB (424 words) - 11:20, 3 March 2020
• Sebastian 2012 Proc Natl Acad Sci U S A
  ...le. Furthermore, Mfn2 deficiency was associated with endoplasmic reticulum stress, enhanced hydrogen peroxide concentration, altered reactive oxygen species ...er-specific Mfn2 KO mice, glucose intolerance, hepatic gluconeogenesis, ER stress, hydrogen peroxide, metabolic homeostasis, ROS, JNK, N-acetylcysteine
  2 KB (329 words) - 16:48, 23 February 2015
• Duskova 2015 Mol Microbiol
  ...nd besides their expected involvement in the cell survival of hyperosmotic stress, they surprisingly both contribute to an efficient survival of hypoosmotic
  2 KB (255 words) - 09:20, 9 November 2016
• Imran 2015 J Neurochem
  ...increases of extracellular lactate, choline and glycerol, and by oxidative stress, while mitochondrial function remains normal for at least 90 minutes. Membr
  3 KB (348 words) - 14:43, 13 November 2017
• Torelli 2015 Free Radic Biol Med
  ...nd RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in ''Saccharomyces cerevisiae''. Free Radic Biol Med 81C:30-7. induction of antioxidant defenses and stress resistance.
  2 KB (253 words) - 17:14, 27 March 2018
• Iglesias-Gonzalez 2013 J Neurosci Methods
  ...endorse this protocol as the method of choice for metabolic and oxidative stress experiments with fresh isolated rat brain mitochondria. ...ain, EDTA, EGTA, Isolation procedure, Mitochondrial respiration, Oxidative stress
  3 KB (349 words) - 14:26, 3 June 2020
• Kleszczynski 2018 Int J Mol Sci
  ...latonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786. ...ch express melatonin receptors (MT1 and MT2) against UVB-induced oxidative stress and mitochondrial dysfunction, including the uncoupling of oxidative phosph
  2 KB (340 words) - 00:51, 10 February 2020
• Keller 2016 Oxid Med Cell Longev
  ...sistent metabolic perturbations in a diabetes phenotype. Overall, nutrient stress in GK SMCs caused a persistent decline in eNOS and mitochondrial function a |injuries=Oxidative stress;RONS
  2 KB (327 words) - 14:52, 13 November 2017
• Thaher 2017 Neurochem Int
  ...teine 684 (C684) of MFN2. Mitochondrial hyperfusion represents an adaptive stress response that confers transient protection by increasing mitochondrial ATP |keywords=Fusion/fission, Hyperfusion, MFN2, Mitochondria, Oxidative stress
  2 KB (351 words) - 15:08, 11 October 2018
• Herholz 2019 Nat Commun
  ...yeast to mammals. However, the underlying molecular mechanisms regulating stress resistance during aging are still largely unknown. Here we identify Krüppe
  2 KB (244 words) - 09:41, 12 August 2019
• Kozlov 2009 Biochim Biophys Acta
  ...se-regulated protein (GRP78) were up-regulated, both typical markers of ER stress. However, GRP78 was down-regulated at the protein level. A pro-apoptotic sh |keywords=Endoplasmic reticulum stress, Gene expression, Inflammatory response, Mitochondria, Proteome analysis
  2 KB (331 words) - 15:15, 20 March 2015
• Munro 2013 Aging Cell
  ...anoxia/reoxygenation, and temperature variations known to elicit oxidative stress. Their mitochondrial electron transport system is also connected to an alte |injuries=Oxidative stress;RONS
  3 KB (376 words) - 16:44, 21 November 2018
• Li 2018 Free Radic Biol Med
  ...Hu M, Tang Z (2018) Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis ''in vitro'' and ''in vivo' ...n vivo'' rely on normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway, suggesting that PCr may be a novel ther
  3 KB (490 words) - 04:27, 1 March 2020
• Loughland 2022 J Exp Biol
  ...d I, Lau GY, Jolly J, Seebacher F (2022) Rates of warming impact oxidative stress in zebrafish (''Danio rerio''). ...erature increase affect mitochondrial bioenergetics and modulate oxidative stress. We exposed zebrafish (''Danio rerio'') to warming from 20°C to 28°C over
  3 KB (364 words) - 10:39, 5 December 2022
• Ziech 2022 Drug Chem Toxicol
  ...g flies, possibly related to disruption of energetic metabolism, oxidative stress, and deregulation of genes implied in growth, sleep, and metabolism. ...y, Dithiocarbamate, Embryotoxicity, Mitochondrial bioenergetics, Oxidative stress
  3 KB (345 words) - 15:38, 28 November 2022
• Drahota 2012 Physiol Res
  ...r mitochondrial permeability transition pore to calcium load and oxidative stress. Physiol Res 61:S165-72. ...etter protected against damaging effects of the calcium load and oxidative stress. We can only speculate that the lower sensitivity to calcium-induced swelli
  2 KB (298 words) - 11:43, 24 February 2015
• Kutschka 2023 Basic Res Cardiol
  ...uchi T, Rabinowitz J, Maack C, Dudek J (2023) Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. https://doi.org/10.1 ...yses revealed that the activation of the eIF2α/ATF4 axis of the integrated stress response upregulates one-carbon metabolism, which diverts glycolytic interm
  3 KB (398 words) - 17:47, 14 November 2023
• Mendoza-Fuentes 2023 PeerJ
  ...cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis. https://doi.org/10.7717/peerj.15586 ...ene suggested that this natural product exerted cytotoxicity via oxidative stress as evidenced in a significantly increase of intracellular ROS levels and in
  3 KB (397 words) - 16:30, 28 June 2023
• Rodriguez 2020 J Gerontol A Biol Sci Med Sci
  ...idative phosphorylation, potentially impacting the management of oxidative stress. Longitudinal studies using the framework of metabolic control analysis hav
  2 KB (364 words) - 19:25, 21 February 2022
• Pokkunuri 2016 Oxid Med Cell Longev
  ...-NADPH oxidase levels were high in control aged rats, suggesting oxidative stress burden in these rats. GP treatment in aged rats restored these parameters t |keywords=Oxidative stress, Grape powder, Blood pressure, Kidney functions
  2 KB (269 words) - 10:24, 23 August 2016
• Miotto 2019 FASEB J
  ...response to muscle disuse, challenge the necessity for increased oxidative stress during inactivity, and establish that ω-3 supplementation preserves oxidat |keywords=Metabolism, Mitochondrial function, Oxidative stress, Buffer Z, Blebbistatin, Amplex Red in muscle fibers
  3 KB (344 words) - 13:20, 7 March 2020
• Abdurrachim 2014 Biochim Biophys Acta
  ...ardiomyopathy in mice is associated with lipotoxicity-associated oxidative stress, fibrosis, and disturbed calcium homeostasis, rather than impaired cardiac
  3 KB (369 words) - 14:27, 27 March 2018
• O2k-Publications: O2k-Fluorometer
  |?Stress
  682 bytes (95 words) - 15:30, 10 June 2020
• Buck 2013 Abstract MiP2013
  ...ading to apoptosis and necrosis. Hypoxic or anoxic stress does not signal stress in turtle brain but rather protective mechanisms with the onset of anoxia. |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  3 KB (416 words) - 10:46, 28 April 2017
• O2k-Publications: Exercise physiology;nutrition;life style
  |?Stress |?Stress
  2 KB (213 words) - 22:34, 19 January 2020
• Poudel 2019 Can J Physiol Pharmacol
  ...p-38 mitogen-activated protein kinase, nuclear factor kappa B (NF-κB), and stress-activated protein kinases/Jun amino-terminal kinases (SAPK/JNK) in C2C12 my
  2 KB (330 words) - 16:17, 11 February 2020
• Uzhachenko 2017 Aging (Albany NY)
  ...s, lack of vigor, inability to accumulate fat, reduced ability to tolerate stress, and premature death. Other prominent pathological changes included low spe |injuries=Oxidative stress;RONS
  2 KB (346 words) - 12:20, 25 June 2019
• AMPK
  ...ion, AMPK upregulates genes involved in oxidative metabolism and oxidative stress resistance by regulating a number of transcription factors which affects th
  2 KB (289 words) - 08:58, 21 May 2012
• Pharaoh 2021 JCSM Rapid Commun
  ...reactive oxygen species production in mouse models of aging and oxidative stress but not denervation. https://doi.org/10.1002/rco2.29 ...ic nerve transection (denervation), and in response to increased oxidative stress (Sod1^-/- mice). Further, we asked whether the mitochondrial-targ
  3 KB (401 words) - 16:23, 4 January 2023
• Schiffer 2016 Am J Physiol Cell Physiol
  ...b>2}O₂ production, higher resistance toward both oxidative stress, and severe hypoxia compared with control cells. These results suggest an i |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (343 words) - 13:42, 7 March 2020
• Sies 2021 Redox Biol
  ...-term (transcriptional/translational) homeostatic mechanisms of stress and stress responses. The redox set point is a variable moving target value, modulated
  2 KB (247 words) - 13:36, 25 April 2022
• Ma 2012 Exp Diabetes Res
  ...ed by β-cell mitochondria as a result of metabolic stress activate several stress-response pathways. This paper focuses on mechanisms whereby ROS affect mito
  2 KB (268 words) - 05:50, 5 November 2023
• Kruse 2015 Aging Cell
  ...raction between dysregulation of respiratory protein expression, oxidative stress, and mitochondrial function with age. |injuries=Oxidative stress;RONS
  3 KB (388 words) - 15:01, 13 November 2017
• Houghton 2018 Free Radic Biol Med
  ...tivity and ETS coupling efficiency under conditions of amplified oxidative stress could reinforce mitochondrial integrity and improve redox status, beneficia
  3 KB (358 words) - 15:17, 10 October 2018
• Chowdhury 2010 Am J Physiol Endocrinol Metab
  ...y and atherogenesis under conditions of hypercholesterolemia and oxidative stress. |keywords=Oxidized lipoproteins, Oxidative stress, Oxygen consumption, Enzymes of the mitochondrial respiratory chain
  3 KB (366 words) - 19:06, 1 April 2018
• Samper 2009 Free Radic Biol Med
  ...Cadenas S, Melov S (2009) Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas. Free Radic Biol Med 46:387-96. |injuries=Oxidative stress;RONS
  2 KB (251 words) - 16:12, 27 March 2018
• Aye 2022 Am J Obstet Gynecol
  ...g the tissue to adapt to developmental changes and respond to preeclampsia stress, whereas the inability to reprogram placental metabolism may result in seve
  2 KB (278 words) - 22:57, 8 November 2023
• Hedges 2019 Comp Biochem Physiol A Mol Integr Physiol
  ...cle mitochondrial function: Increasing metabolic power increases oxidative stress. Comp Biochem Physiol A Mol Integr Physiol 230:115-21. ...ee radical production. To examine how metabolic requirements and oxidative stress vary between species, we explored the variation in flight mechanics and met
  3 KB (371 words) - 13:51, 7 March 2020
• Kucera 2012 J Gastroenterol Hepatol
  ...-1 and HFGD groups at 24 h after acetaminophen application. Mild oxidative stress induced by acetaminophen was confirmed by measurement of malondialdehyde. L |keywords=Acetaminophen, Cytokines, Fatty liver, Hepatotoxicity, Oxidative stress
  3 KB (364 words) - 10:26, 18 March 2020
• Kezic 2016 Oxid Med Cell Longev
  ...on and progression of kidney ischemia/reperfusion injury linking oxidative stress, inflammation, and cell death. The dependence of kidney proximal tubule cel
  2 KB (279 words) - 19:12, 25 April 2023
• Locatelli 2020 FASEB J
  ...elial cells, we have recently shown the sequential intervention of various stress proteins which are crucial to prevent apoptosis and maintain cell function.
  2 KB (246 words) - 14:30, 14 January 2020
• Yang 2021 Springer
  ...ose metabolism, and lipid metabolism. In: Huang C, Zhang Y (eds) Oxidative stress. Springer, Singapore. https://doi.org/10.1007/978-981-16-0522-2_9 ...glucose metabolism increases the production of ROS and enhances oxidative stress by glucose auto-oxidation and glycosylation of proteins and activated the p
  2 KB (293 words) - 23:17, 6 November 2023
• Nunn 2022 Biomedicines
  ...irus. Resolution is normally achieved after viral clearance as the initial stress activates a hormetic negative feedback mechanism. It is therefore possible |injuries=Oxidative stress;RONS
  2 KB (269 words) - 11:50, 9 July 2023
• Severin 2013 Abstract MiP2013
  ...Together, it suggests that Var1 physically interacts with mtDNA and under stress negatively regulates its maintenance [1].
  3 KB (365 words) - 11:23, 28 April 2017
• Brown 2012 Am J Physiol Regul Integr Comp Physiol
  ...ism is suppressed during torpor and how this suppression affects oxidative stress. In liver and skeletal muscle, state 3 respiration measured at 37 °C with ...roxide, Top-down elasticity analysis, Oxidative phosphorylation, Oxidative stress
  3 KB (376 words) - 17:05, 9 November 2017
• Mueller 2012 PLoS One
  ...h hydrogen peroxide, indicating a higher capability to cope with oxidative stress. |injuries=Oxidative stress;RONS
  2 KB (272 words) - 14:16, 26 March 2018
• R/E control ratio
  |?Stress |?Stress
  2 KB (256 words) - 01:19, 31 December 2020
• Magga 2019 Mol Ther
  ...2B-Fc provided beneficial effects on cardiac function in prolonged cardiac stress in cardiotoxicity model. By blocking myostatin, ACVR2B-Fc potentially reduc
  2 KB (358 words) - 11:46, 25 July 2019
• Delfinis 2022 JCI Insight
  ...ophy during cancer cachexia and is linked to muscle-specific mitochondrial stress. https://doi.org/10.1172/jci.insight.155147 ...tochondrial alterations that could involve adaptive responses to metabolic stress. Eventual muscle-specific restorations in force and bioenergetics highlight
  3 KB (368 words) - 19:11, 15 March 2023
• Kayastha 2023 MiPschool Obergurgl
  ...alis'' Kaczmarek, Mioduchowska, Poprawa & Roszkowska, 2020 to heat related stress. |keywords=water bears, Tardigrada, Eutardigrada, heat stress, mitochondria
  2 KB (265 words) - 16:08, 28 June 2023
• King 2016 Redox Biol
  |abstract=Mitochondrial dysfunction and bioenergetic stress play an important role in the etiology of alcoholic liver disease. Previous ...f key mitochondrial bioenergetic parameters and the attenuation of hypoxic stress.
  3 KB (380 words) - 12:09, 8 November 2016
• Skulachev 1998 Biochim Biophys Acta
  |injuries=Oxidative stress;RONS
  752 bytes (98 words) - 15:00, 27 March 2018
• Roach 2022 Abstract Bioblast
  ...aur T, Stöggl W, Kranner I (2022) Retrograde signalling during high light stress involves reactive carbonyl / electrophile species. '''Bioblast 2022: BEC In ...ific role of (¹O₂ in RES signalling under high light stress. Finally, a comparison to differential gene expression in response to H<sub
  5 KB (708 words) - 08:30, 28 July 2022
• Lou 2017 Physiol Rep
  ...sing its capacity for fatty acid oxidation. Along with increased oxidative stress, this may represent one of the earliest signs of dysfunction that will ulti ...tty acid metabolism, Fructose, Insulin resistance, Mitochondria, Oxidative stress, Sirtuins, Type‐2 diabetes mellitus
  3 KB (375 words) - 14:55, 11 December 2017
• Lancel 2009 J Pharmacol Exp Ther
  respiration, and redox status. Oxidative stress was evaluated by measurements of mitochondrial hydrogen peroxide, carbonyl ...ting that administration of CORM-3 during sepsis elicited a mild oxidative stress response that stimulated mitochondrial biogenesis with [[PGC-1alpha|(PGC)-1
  3 KB (359 words) - 11:49, 22 December 2020
• LeBel 1992 Chem Res Toxicol
  ...orescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5:227-31. ...However, DCFH remains an attractive probe as an overall index of oxidative stress in toxicological phenomena.
  2 KB (263 words) - 17:32, 13 April 2022
• Laehteenmaeki 2022 Physiol Rep
  ...ular respiration, but the level of peripheral muscle fatigue and metabolic stress could be explaining factors.
  3 KB (368 words) - 15:22, 31 August 2022
• Llesuy 1994 Free Radic Biol Med
  ...-Flecha B, Peralta J, Carreras MC, Poderoso JJ, Boveris A (1994) Oxidative stress in muscle and liver of rats with septic syndrome. Free Radic Biol Med 16:44
  458 bytes (66 words) - 17:44, 16 January 2021
• Hyperoxia
  ...under tissue conditions in vivo. Hyperoxic conditions may impose oxidative stress and may increase maximum aerobic performance.
  738 bytes (92 words) - 14:47, 21 October 2021
• IN Haldia Chakrabarti S
  |keyword=Neuropathology, Oxidative stress
  755 bytes (93 words) - 09:28, 2 December 2019
• Liu 2019 J Ethnopharmacol
  ...2',7'-dichlorodihydrofluorescein diacetate staining. PD-related oxidative stress was simulated by paraquat and rotenone, and mitochondrial membrane potentia ...tochondrial function and protect mitochondria from PD-associated oxidative stress by activating the mitochondrial unfolded protein response (UPR^mt
  3 KB (475 words) - 11:26, 3 March 2020
• Mikulas 2018 Dent Mater
  ...glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e1 ...that dental resin monomers lower cellular viability and provoke oxidative stress. Reactive oxygen species (ROS) formation has a key role in triethylene glyc
  3 KB (386 words) - 10:24, 11 March 2020
• Wu 2017b FASEB J
  ...us exercise regimens on platelet mitochondrial bioenergetics under hypoxic stress. ...e phosphorylation and thrombin generation (TG) of platelets during hypoxic stress. Twenty-four sedentary males were randomized to perform either aerobic inte
  2 KB (273 words) - 14:11, 2 March 2020
• Krebiehl 2010 PLoS One
  ...a rare cause of familial PD. Although a critical role of DJ-1 in oxidative stress response and mitochondrial function has been recognized, the effects on mit |keywords=Parkinson's disease (PD), Oxidative stress response, Mitochondria, Lysosomes, DJ-1, ROS, Mouse embryonic fibroblasts (
  3 KB (359 words) - 15:38, 9 November 2016
• Cruz-Gregorio 2022 Antioxidants (Basel)
  ...ON, Sciutto E, Fragoso G, Pedraza-Chaverri J (2022) GK-1 Induces oxidative stress, mitochondrial dysfunction, decreased membrane potential, and impaired auto ...</sub>) production, GSSG, and protein carbonyl content, inducing oxidative stress (OS) in tumoral tissues. This imbalance between reactive oxygen species (RO
  3 KB (362 words) - 12:05, 24 January 2023
• Lee 2010 Curr Biol
  ...sion and promote longevity. In this way, HIF-1 appears to link respiratory stress in the mitochondria to a nuclear transcriptional response that promotes lon |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (265 words) - 10:10, 9 November 2016

View (previous 500 | next 500) (20 | 50 | 100 | 250 | 500)